Results 101 to 110 of about 4,425 (166)

Hipertansif Hastalarda Kognitif Fonksiyonların Değerlendirilmesi ve Serum Midkine Düzeyleriyle İlişkisi

open access: yes, 2017
Amaç: Hipertansiyon (HT) demans ile ilişkili risk faktörlerinden biridir. Çalışmanın amacı, HT'lu hastalarda kognitif fonksiyonlar ve serum midkine düzeyleri ile ilişkisini araştırmaktır.
Güzel, Eda Çelik   +6 more
core  

Cytokines and chemokines expression in serum of patients with neuromyelitis optica

open access: yesNeuropsychiatric Disease and Treatment, 2019
Nanping Ai,* Hongjuan Liu,* Huanfen Zhou, Dahe Lin, Junqing Wang, Mo Yang, Honglu Song, Mingming Sun, Quangang Xu, Shihui Wei Department of Ophthalmology, Chinese PLA General Hospital, Beijing 100853, People’s Republic of China *These authors ...
Ai NP   +9 more
doaj  

Struktur und biomechanische Eigenschaften von Ulna und Tibia nach mechanisch induziertem Knochenremodeling in Midkine-defizienten-Mäusen

open access: yes, 2011
Es ist bekannt, dass die mechanische Belastung über die Aktivierung verschiedener Signalmoleküle und Signaltransduktionswege einen Einfluss auf das Knochenremodeling hat.
Pahl, Marcus Christopher
core   +1 more source

Chondroitin Sulfate Tetrasaccharides: Synthesis, Three-Dimensional Structure and Interaction with Midkine

open access: yes, 2017
The biological activity of midkine, a cytokine implicated in neuro- and tumourigenesis, is regulated by its binding to glycosaminoglycans (GAGs), such as heparin and chondroitin sulfate (CS).
Macchione, Giuseppe   +6 more
core   +1 more source

Urine and serum midkine levels in an Australian chronic kidney disease clinic population: an observational study

open access: yes, 2017
Background and objectives The cytokine midkine (MK) is pathologically implicated in progressive chronic kidney disease (CKD) and its systemic consequences and has potential as both a biomarker and therapeutic target.
Comeau, Drew C   +36 more
core   +1 more source

Deciphering the Acetabular Labrum's Cellular Atlas: MDK Inhibition as a Novel Therapeutic Method for Developmental Dysplasia of the Hip

open access: yesAdvanced Science
DDH is far more than just a contributing factor to hip osteoarthritis; it represents a formidable challenge to the health of infants and young children.
Runze Yang   +10 more
doaj   +1 more source

Midkine: A Cancer Biomarker Candidate and Innovative Therapeutic Approaches

open access: yesEuropean Journal of Breast Health
Midkine (MDK) is a protein that contributes to both physiological and pathological processes. Several studies provide insight into the different roles of MDK in development, tissue repair, neural plasticity, and health and disease processes.
Berna Yıldırım   +2 more
doaj   +1 more source

Amniotic fluid midkine and pleiotrophin concentrations correlated with each other.

open access: yes, 2016
Midkine concentrations were positively correlated with pleiotrophin concentrations in amniotic fluid (R = 0.6, P < 0.001), using diagnostic category as a covariate.
Gai Yan (2614453)   +7 more
core   +1 more source

Midkine in Inflammatory and Toxic Conditions

open access: yes, 2013
Midkine (MK) is a member of midkine family which is composed of MK and pleotrophin (PTN). MK behaves like a cytokine and growth factor, promotes the proliferation, differentiation, survival, adhesion, migration of cells.
Yazihan, Nuray
core   +1 more source

High effective detection and discoveries of novel truncations of midkine in tumors [PDF]

open access: yes, 2006
Midkine是一种肝素结合性生长因子,属于Midkine家族。Midkine家族由2个因子组成,即中肾因子(midkine,MK)和多效营养因子(pleiotrophin,PTN)。MK在胚胎期广泛表达,在成年组织中的表达则仅限于肾脏和小肠上皮。近年的研究发现MK在恶性肿瘤组织中有异常的高表达,这种现象没有组织特异性,这与P53突变体非常相似。MK有多种生物学功能,在胚胎期它能促进正常细胞的生长和分化,尤其可促进神经细胞的发育,在成年期有激发某些细胞分化的激素样作用,维持肾脏的正常功能 ...
陶萍
core  

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