Results 111 to 120 of about 6,907 (199)

Endocannabinoid receptor blockade increases vascular endothelial growth factor and inflammatory markers in obese women with polycystic ovary syndrome [PDF]

, 2016
© 2016 John Wiley & Sons Ltd Context: Animal studies suggest that cannabinoid receptor-1 (CB-1) blockade reduces inflammation and neovascularization by decreasing vascular endothelial growth factor (VEGF) levels associated with a reduction in ...
Atkin, Stephen L., Coady, Anne-Marie, Javed, Zeeshan, Kilpatrick, Eric S., Sathyapalan, Thozhukat   +4 more
core   +1 more source

Use of retinoids during oocyte maturation diminishes apoptosis in caprine embryos [PDF]

, 2015
Exposure of caprine oocytes and embryos to retinoids enhances embryonic development, but the mechanisms governing this phenomenon have not been characterised.
Cantanhêde, Ludymila F., Chaves, Ricardo M., Conceição, Juliana C. Z., Ferreira-Silva, José C., Lima, Paulo F., Moura, Marcelo T., Oliveira, Marcos A. L., Ramos-Deus, Pamela, Silva, Priscila G. C.   +8 more
core   +1 more source

Role of noncoding RNA in vascular remodelling [PDF]

, 2016
Purpose of review: Noncoding RNAs (ncRNAs), such as microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are becoming fundamentally important in the pathophysiology relating to injury-induced vascular remodelling.
Baker, Andrew H., Bradshaw, Angela C., Deng, Lin   +2 more
core   +1 more source

Pregnancies and improved early embryonic development with bovine oocytes matured in vitro with 9-cis-retinoic acid [PDF]

, 2010
Retinoids have an important role in cell growth, morphogenesis and differentiation. In the present study the developmental potential of bovine oocytes was examined after in vitro maturation in the presence of 9-cis-retinoic acid, a vitamin A metabolite ...
Duque, Paloma, Díez, Carmen, Facal, Nieves, Gómez, Enrique, Hidalgo, C.O. (Carlos)   +4 more
core  

Frontiers in Pigment Cell and Melanoma Research

, 2018
We identify emerging frontiers in clinical and basic research of melanocyte biology and its associated biomedical disciplines. We describe challenges and opportunities in clinical and basic research of normal and diseased melanocytes that impact current ...
Birlea, Stanca, Bosenberg, Marcus W., Box, Neil F., Brash, Douglas, Cassidy, Pamela B., Chen, Suzie, D'Orazio, John August, Filipp, Fabian V., Fujita, Mayumi, Goh, Boon-Kee, Herlyn, Meenhard, Indra, Arup K., Larue, Lionel, Leachman, Sancy A., Liu-Smith, Feng, Manga, Prashiela, Montoliu, Lluis, Norris, David A., Poole, Caroline Le, Shellman, Yiqun, Smalley, Keiran S. M., Spritz, Richard A., Sturm, Richard A., Swetter, Susan M., Terzian, Tamara, Wakamatsu, Kazumasa, Weber, Jeffrey S.   +26 more
core   +1 more source

Ovariectomy Alters Gene Expression of the Hippocampal Formation in Middle-Aged Rats [PDF]

, 2016
Ovarian hormones regulate the transcriptome of the hippocampus and modulate its functions. During 29 menopause, this complex signaling declines, leading to impaired learning and memory.
Hrabovszky, Erik, Kalló, Imre, Liposits, Zsolt, Solymosi, Norbert, Sárvári, Miklós   +4 more
core   +1 more source

Connecting Metainflammation and Neuroinflammation Through the PTN-MK-RPTPβ/ζ Axis: Relevance in Therapeutic Development

Frontiers in Pharmacology, 2019
Inflammation is a common factor of pathologies such as obesity, type 2 diabetes or neurodegenerative diseases. Chronic inflammation is considered part of the pathogenic mechanisms of different disorders associated with aging.
Gonzalo Herradon, M. Pilar Ramos-Alvarez, Esther Gramage   +2 more
doaj   +1 more source

Enhancement of developmental capacity of meiotically inhibited bovine oocytes by retinoic acid [PDF]

, 2012
BACKGROUND: Although high vitamin A may be teratogenic to the embryo, retinol has been shown to support oocyte developmental potential in vivo. Similarly, addition of retinol metabolite 9-cis-retinoic acid to in-vitro cultured oocytes could promote ...
Carneiro, G., Duque, Paloma, Díez, C., Facal, Nieves, Gómez, E., Hidalgo, C.O. (Carlos), Lorenzo, P.L. (Pedro), Royo, L.J. (Luis)   +7 more
core  

Midkine: A Cancer Biomarker Candidate and Innovative Therapeutic Approaches

European Journal of Breast Health
Midkine (MDK) is a protein that contributes to both physiological and pathological processes. Several studies provide insight into the different roles of MDK in development, tissue repair, neural plasticity, and health and disease processes.
Berna Yıldırım, Kudret Kulak, Ayhan Bilir   +2 more
doaj   +1 more source

Serum Midkine as a Potential Biomarker Associated with Disease Severity and Remodeling-Related Mediators in Children with Asthma

Journal of Asthma and Allergy
Yongtian Xu,* Lixia Zhao,* Yingying Mi, Yi Ge, Yanfang Guo Department of Pediatrics, Shanghai University of Medicine and Health Science Affiliated Gongli Hospital, Shanghai, People’s Republic of China*These authors contributed ...
Xu Y, Zhao L, Mi Y, Ge Y, Guo Y
doaj