Results 101 to 110 of about 3,058 (153)

Midkine as a factor to counteract the deposition of amyloid β-peptide plaques: in vitro analysis and examination in knockout mice [PDF]

, 2011
Background Midkine is a heparin-binding cytokine involved in cell survival and various inflammatory processes. Midkine accumulates in senile plaques of patients with Alzheimer's disease, while it counteracts the cytotoxic effects of amyloid β-peptide and
Chen, Lan, Ichihara-Tanaka, Keiko, Kimura, Terutoshi, Muramatsu, Takashi, Muramatsu1, Hisako, Yokoi, Katsunori   +5 more
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Midkine and Melanoma Metastasis : A Malevolent Mix [PDF]

, 2017
Using an in vivo reporter for lymphangiogenesis, a recent study in Nature from Olmeda et al. ( 2017) describes a new subset of melanomas that induce systemic pre-conditioning of distant organs for formation of tumor metastatic niches, and identifies the ...
Alitalo, Kari, Karaman, Sinem
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Serum circulating proteins from pediatric patients with dilated cardiomyopathy cause pathologic remodeling and cardiomyocyte stiffness

JCI Insight, 2021
Dilated cardiomyopathy (DCM) is the most common form of cardiomyopathy and main indication for heart transplantation in children. Therapies specific to pediatric DCM remain limited due to lack of a disease model.
Danielle A. Jeffrey, Julie Pires Da Silva, Anastacia M. Garcia, Xuan Jiang, Anis Karimpour-Fard, Lee S. Toni, Thomas Lanzicher, Brisa Peña, Carissa A. Miyano, Karin Nunley, Armin Korst, Orfeo Sbaizero, Matthew R.G. Taylor, Shelley D. Miyamoto, Brian L. Stauffer, Carmen C. Sucharov   +15 more
doaj   +1 more source

Serum Midkine, estimated glomerular filtration rate and chronic kidney disease-related events in elderly women: Perth Longitudinal Study of Aging Women [PDF]

, 2020
© 2020, The Author(s). Midkine (MDK), a heparin-binding growth factor cytokine, is involved in the pathogenesis of kidney diseases by augmenting leukocyte trafficking and activation.
Byrnes, Elizabeth, Cao, Qi, Lee, Vincent W., Lewis, Joshua R., Lim, Wai H., Prince, Richard L., Raymond, Warren D., Robertson, Graham R., Wang, Jeffrey, Wong, Germaine, Zhu, Kun   +10 more
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Plasma midkine concentrations in healthy children, children with increased and decreased adiposity, and children with short stature.

PLoS ONE, 2019
BackgroundMidkine (MDK), one of the heparin-binding growth factors, is highly expressed in multiple organs during embryogenesis. Plasma concentrations have been reported to be elevated in patients with a variety of malignancies, in adults with obesity ...
Youn Hee Jee, Kun Song Lee, Shanna Yue, Ellen W Leschek, Matthew G Boden, Aysha Jadra, Anne Klibanski, Priya Vaidyanathan, Madhusmita Misra, Young Pyo Chang, Jack A Yanovski, Jeffrey Baron   +11 more
doaj   +1 more source

Improved resistance to Eimeria acervulina infection in chickens due to dietary supplementation with garlic metabolites [PDF]

, 2017
The effects of a compound including the secondary metabolites of garlic, propyl thiosulphinate (PTS) and propyl thiosulphinate oxide (PTSO), on the in vitro and in vivo parameters of chicken gut immunity during experimental Eimeria acervulina infection ...
Bravo, David, Kim, Duk Kyung, Lee, Sung Hyen, Lillehoj, Erik P., Lillehoj, Hyun S.   +4 more
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Blocking MIF secretion enhances CAR T-cell efficacy against neuroblastoma [PDF]

INTRODUCTION: Chimeric antigen receptor (CAR) T-cell therapy is a promising and innovative cancer therapy. However, immunosuppressive tumor microenvironments (TME) limit T cell persistence and durable efficacy.
Anderson, John, Barisa, Marta, Bosse, Kristopher R, Catena, Xavier, Dekker, Frank J, Grothusen, Grant P, Hains, Peter G, Himsworth, Courtney, Kalaitsidou, Elisavet, Kalmeijer, Yannine J, Margaritis, Thanasis, Matlaga, Stephanie, McIntyre, Brendan, Molenaar, Jan J, Muller, Henrike, Pascual-Pasto, Guillem, Reddel, Roger R, Robinson, Phillip J, Schild, Linda G, Shah, Rivani, Soengas, María S, Strijker, Josephine G M, Visser, Lindy L, Wienke, Judith, Wu, Wei, Zhao, Chunlong, Zhong, Qing   +26 more
core   +1 more source

Midkine (MDK) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Changes of Serum Midkine as a Dynamic Prognostic Factor in Detection for Thyroid Cancer and Comparison with Fine-Needle Aspiration [PDF]

Background: Midkine plays a significant role in the pathophysiology of malignant and other diseases since it is involved in a number of physiological processes, including development, reproduction, and repair.
Al-Rubaiawi, Hadel Kareem, Alhelfy, Sajid H., Mohamed, Raid J., Yones, Marwah S.   +3 more
core   +2 more sources

The midkine family in cancer, inflammation and neural development [PDF]

, 2005
2005-06The midkine (MK) family consists of only two members, namely MK and pleiotrophin (PTN). MK and PTN share receptors and biophysical characteristics, such as a heparin-binding property.
10189, Kadomatsu, Kenji
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