Upregulation of Cytokines Midkine and Pleiotrophin in Keloids
The 58th Annual Medical Student Research Forum at UT Southwestern Medical Center (Tuesday, January 21, 2020, 3-6 p.m., D1.600)Keloids are benign proliferative scars that are exaggerated responses to cutaneous wound healing.
Marella, Pooja
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Evidence of the role of Midkine and Pleiotrophin in the pathogenesis of Familial Mediterranean Fever. [PDF]
Abdallah ZY +7 more
europepmc +1 more source
Midkine and pleiotrophin in glioma: From mechanistic insights to therapeutic potential. [PDF]
Lachota M, Zielniok K, Zagożdżon R.
europepmc +1 more source
Midkine as a therapeutic node in NF1-driven neuro‑oncology: Biology, biomarkers, and translational strategies. [PDF]
Nair HB, Subramani R, Lakshmanaswamy R.
europepmc +1 more source
MDK Activates the PI3K/AKT Axis to Induce AP2A1 Expression and Epithelial-Mesenchymal Transition in Colorectal Cancer. [PDF]
Li T +8 more
europepmc +1 more source
Remote neuromuscular electrical stimulation upregulates MDK to enhance macrophage efferocytosis <i>via</i> LRP1 in wound healing. [PDF]
Zong L +13 more
europepmc +1 more source
N<sup>6</sup>‑methyladenosine reader insulin‑like growth factor 2 mRNA‑binding protein 2 promotes abnormal proliferation of colonic epithelial cells in type 2 diabetes mellitus by regulating midkine. [PDF]
Li J, Xie Q, Xu J.
europepmc +1 more source
Midkine as a novel prognostic and therapeutic target in meningioma: insights from single-cell analysis and organoid-based drug validation. [PDF]
Li PR +6 more
europepmc +1 more source
LRP1 activated by AT2 cell-secreted MDK inhibits fibrotic ferroptosis in idiopathic pulmonary fibrosis. [PDF]
Hua W +7 more
europepmc +1 more source
Pleiotrophin and Midkine Confer Metastatic Ability to Disseminated Breast Cancer Cells
Metastasis is a highly inefficient process with several rate limiting steps. It is estimated that only 0.01% of disseminating tumor cells are successful in forming overt metastasis.
Ganguly, Debolina
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