Aim. To investigate the effects of cytoprotection with mildronate (Grindex, Latvia) on oxidative processes and endothelial function in elderly patients with ischemic heart disease (IHD). Material and methods.
A. V. Shabalin +4 more
doaj +1 more source
Возможности фармакологической коррекции эндотелиальной дисфункции и коронарного кровотока с помощью милдроната и мексикора [PDF]
В результате исследования эндотелиопротективной, кардиоиротективиой и коронаролитической активности препаратов "Мексидол" и "Мексикор" установлена выраженная коррекция эндотелиальной ...
Гончаров, Н. Ф. +4 more
core +1 more source
Корреляционная взаимосвязь между гамма-фоном среды и физиологическими показателями у больных артериальной гипертензией с различным темпераментом [PDF]
Выявление и оценка характера корреляционной связи между среднегодовыми значениями гамма-фона окружающей среды (в границах нормы) и физиологическими показателями у больных артериальной гипертензией мужчин с различным темпераментом и тревожностью ...
Васендин, Д. В. +2 more
core +1 more source
Inhibition of carnitine acetyltransferase by mildronate, a regulator of energy metabolism
Carnitine acetyltransferase (CrAT; EC 2.3.1.7) catalyzes the reversible transfer of acetyl groups between acetyl-coenzyme A (acetyl-CoA) and L-carnitine; it also regulates the cellular pool of CoA and the availability of activated acetyl groups. In this study, biochemical measurements, saturation transfer difference (STD) nuclear magnetic resonance ...
Kristaps, Jaudzems +7 more
openaire +2 more sources
INFLUENCE OF MILDRONATE ON EFFICIENCY OF ANTIANGINAL THERAPY IN PATIENTS WITH STABLE BURDEN ANGINA
Aim. To study influence of mildronate (M) on treatment efficiency of patients with ischemic heart disease (IHD), receiving standard antianginal therapy (AAT)Materials and methods.
N. P. Kutishenko +6 more
doaj +1 more source
Аденозинтрифосфорная кислота в крови как маркер состояния энергетического обмена миокарда при оценке энергосберегающих эффектов метаболических корректоров [PDF]
Целью исследования явилось определение адекватного маркера состояния энергетического обмена миокарда для оценки энергосберегающих эффектов метаболических корректоров при экспериментальной ишемии ...
Горбач, Т. В. +4 more
core
Aim. Assessment of Ipigrix effectiveness (patented name of Ipidacrine) taking as a self-administered and in combination with Mildronate (patented name of Meltedonium) in patients with type 2 diabetes mellitus suffering from diabetic polyneuropathy ...
Olesya Kikhtyak +2 more
doaj +1 more source
Carnitine and γ-Butyrobetaine Stimulate Elimination of Meldonium due to Competition for OCTN2-mediated Transport [PDF]
Publisher Copyright: © 2016 Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society)Meldonium (3-(2,2,2-trimethylhydrazinium)propionate) is the most potent clinically used inhibitor of organic cation transporter 2 (OCTN2 ...
Bieber +31 more
core +1 more source
Cardioprotective measures in patients with cardiovascular risk factors and polymorbidity
4th international educational forum «Russian Days of the Heart» took place in St. Petersburg, 22 June 2022. Its program included a satellite symposium «Actual cardioneurology: cardiovascular risk factors and polymorbidity» that was held with the support ...
article Editorial
doaj
Decrease in Long-Chain Acylcarnitine Tissue Content Determines the Duration of and Correlates with the Cardioprotective Effect of Methyl-GBB [PDF]
Publisher Copyright: © 2017 Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society)Ischaemia in the heart is accompanied by the accumulation of long-chain acylcarnitines (LCACs) which is one of the multiple factors that ...
Aguer +33 more
core +2 more sources

