Pharmacological correction of the sequelae of acute alcohol-induced myocardial damage with new derivatives of neuroactive amino acids coupled with the blockade of the neuronal NO synthase isoform [PDF]
, 2022 Introduction: Acute alcohol intoxication (AAI) induces a number of myocardial disorders, which result in mitochondrial dysfunction in cardiomyocytes, oxidative stress, and decreased cardiac contractility.
Aida S. Kucheryavenko +7 more
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Изучение противоишемической активности в ряду производных 3-(2, 2, 2-триметилгидразиний) пропионата при моделировании коронароокклюзионного инфаркта миокарда [PDF]
, 2011 Результаты экспериментального исследования влияния 3-(2, 2, 2-триметилгидразиний) пропионата и его производных на площадь некротизированного миокарда левого желудочка при моделировании коронароокклюзионного инфаркта миокардаyesБелгородский ...
Даниленко, Л. М. +4 more
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Inhibition of L-carnitine biosynthesis and transport by methyl-γ-butyrobetaine decreases fatty acid oxidation and protects against myocardial infarction [PDF]
, 2015 Publisher Copyright: © 2014 The British Pharmacological Society.Background and Purpose The important pathological consequences of ischaemic heart disease arise from the detrimental effects of the accumulation of long-chain acylcarnitines in the case of ...
Abdul-Ghani +43 more
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Rat spinal ganglia in assessment of protective action of antioxidants: A morphological study
Medicina, 2017 Background and objective: Mercury pollution is one of the most pressing environmental problems. Therefore, the impact of mercury on human body, the nervous system in particular, remains topical.
Liudmyla M. Sokurenko +4 more
doaj +1 more source
Mildronate improves cognition and reduces amyloid‐β pathology in transgenic Alzheimer's disease mice [PDF]
Journal of Neuroscience Research, 2013 Mildronate, a carnitine congener drug, previously has been shown to provide neuroprotection in an azidothymidine‐induced mouse model of neurotoxicity and in a Parkinson's disease rat model. The aim of this study was to investigate the effects of mildronate treatment on cognition and pathology in Alzheimer's disease (AD) model mice (APPSweDI ...
Ulrika, Beitnere +5 more
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Mildronate's protective effects in the peripheral nervous system : Stavudine-induced neuropathy and formalin-induced inflammation [PDF]
, 2010 Funding Information: This work was supported by the Latvian Council of Science Grant Nr. 05-1418; ESF Grant ESS2004/3; Contract No. 453, between the Latvian Institute of Organic Synthesis and the Joint Stock Company “Grindex”; Contract No.
Isajevs, Sergejs +7 more
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Эндотелиопротекторное действие милдроната и его производных при моделировании L-NAME индуцированного дефицита оксида азота [PDF]
, 2011 Результаты исследования 4 химических производных пропионата на лабораторных крысахyesБелгородский государственный ...
Даниленко, Л. М. +4 more
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Meldonium: drug which brought disrepute to sport [PDF]
, 2017 World of sports have been rocked by doping scandals every now and then and World Anti-Doping Agency(WADA) has banned several offending drugs at different times to counter this menace.
Das, Smita +2 more
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Возможности фармакологической коррекции эндотелиальной дисфункции и коронарного кровотока с помощью милдроната и мексикора [PDF]
, 2012 В результате исследования эндотелиопротективной, кардиоиротективиой и коронаролитической активности препаратов "Мексидол" и "Мексикор" установлена выраженная коррекция эндотелиальной ...
Гончаров, Н. Ф. +4 more
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Mildronate treatment alters γ-butyrobetaine and l -carnitine concentrations in healthy volunteers [PDF]
, 2011 Objectives In this study, we aimed to investigate the effects of long-term administration of the cardioprotective drug mildronate on the concentrations of l-carnitine and γ-butyrobetaine in healthy volunteers.
Bieber +40 more
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