EFFICIENCY OF MILDRONATE IN RATS OF DIFFERENT AGE WITH EXPERIMENTAL-INDUCED MYOCARDIAL ISCHEMIA
Under experimental myocardial ischemia in rats of 10 months treatment with mildronate resulted in essential changes in metabolism of cardiomyocites. This includes stimulation of aerobic and anaerobic ways of power supply of heart cells: activation of glycolysis, oxidative phosphorylation and oxidative pyruvate decarboxylation with restoration of ...
V G, Kukes +4 more
openaire +3 more sources
Experience with mildronate in cerebrovascular diseases
Over the past years, results of various clinical trials of drugs demonstrating their efficacy in the treatment of cardiovascular diseases have been published. The article discusses the results of clinical use of Mildronate (meldonium) in the treatment of ischemic brain injuries; the results of trials show that the medicine has a cytoprotective effect ...
openaire +1 more source
A randomized study of the state of stiffness parameters arteries wall (CAVI — cardio-ankle vascular index), AI (augmentation index) PEP (duration of the voltage of the left ventricle) using «VaSera-1000» («Fukuda Denshi», Japan) in primary hypertension ...
V. P. Mikhin +3 more
doaj +1 more source
New views of mildronate use for the prevention and correction of impairment of adaptive processes
Protective and normalizing mildronate action on the level of non enzyme kation proteins in the neurophils and contents of kateholamins in erythrocytes were revealed on the experimental model of the emotional-pain stress.
L V Logunova
doaj
TRIMETAZIDINE AND MILDRONATE AS DIRECT ACTION Β2 - ADRENOSENSIBILIZERS (EXPERIMENTAL EVIDENCE)
Trimetazidine and mildronate as direct action β2 - adrenosensibilizers (experimental evidence).
V. I. Tsirkin +6 more
doaj
PHARMACEUTICAL CORRECTION OF VASCULAR DISTURBANCES IN PATIENTS WITH ARTERIAL HYPERTENSION
Aim: To study vascular stiffness and elasticity, microcirculation (MC) parameters, and mildronate effects in patients with arterial hypertension (AH). Material and methods.
L. A. Khaisheva +4 more
doaj
Comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatment
The study is focused on comparative effectiveness of myocardial cytoprotectors in chronic heart failure (CHF) treatment. In total, 120 patients with Functional Class (FC) II-III CHF were divided into two groups.
G. G. Semenkova, L. V. Kokoreva
doaj
Altered Blood Molecular Markers of Cardiovascular Function in Rats after Intrauterine Hypoxia and Drug Therapy. [PDF]
Popazova O +4 more
europepmc +1 more source
New views of mildronate use for the prevention and correction of impairment of adaptive processes
Protective and normalizing mildronate action on the level of non enzyme kation proteins in the neurophils and contents of kateholamins in erythrocytes were revealed on the experimental model of the emotional-pain stress.
L V Logunova
doaj
Cardioprotective Activity of Pharmacological Agents Affecting NO Production and Bioavailability in the Early Postnatal Period after Intrauterine Hypoxia in Rats. [PDF]
Popazova O +5 more
europepmc +1 more source

