Results 31 to 40 of about 354 (165)

Rat spinal ganglia in assessment of protective action of antioxidants: A morphological study

Medicina, 2017
Background and objective: Mercury pollution is one of the most pressing environmental problems. Therefore, the impact of mercury on human body, the nervous system in particular, remains topical.
Liudmyla M. Sokurenko, Mariya O. Savchyna, Viktor I. Litus, Rostyslav F. Kaminsky, Yurii B. Ehaikovsky   +4 more
doaj   +1 more source

EFFECT OF CYTOPROTECTION ON THE OXIDATIVE PROCESSES AND ENDOTHELIAL FUNCTION IN ELDERLY PATIENTS WITH ISCHEMIC HEART DISEASE

Рациональная фармакотерапия в кардиологии, 2016
Aim. To investigate the effects of cytoprotection with mildronate (Grindex, Latvia) on oxidative processes and endothelial function in elderly patients with ischemic heart disease (IHD). Material and methods.
A. V. Shabalin, Yu. I. Ragino, S. A. Lyubimtseva, Ya. V. Polonskaya, M. V. Ivanova   +4 more
doaj   +1 more source

COMPARATIVE EFFECTIVENESS OF CARDIOCYTE PROTECTORS IN COMPLEX MANAGEMENT OF ARTERIAL HYPERTENSION

Российский кардиологический журнал, 2009
The study investigated the effects of cardiocyte protectors, mexicor and mildronate, in combination with ACE inhibitors, on blood levels of lipid peroxidation products, vascular endothelial function, circadian profile of blood pressure, and left ...
F. E. Khlebodarov, V. P. Mikhin, A. V. Gorlova   +2 more
doaj  

EFFECTS OF TRIMETHYLAMINE-N-OXIDE INHIBITOR IN COMBINATION WITH ANTICHOLINESTERASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Праці Наукового товариства імені Шевченка. Медичні науки, 2018
Aim. Assessment of Ipigrix effectiveness (patented name of Ipidacrine) taking as a self-administered and in combination with Mildronate (patented name of Meltedonium) in patients with type 2 diabetes mellitus suffering from diabetic polyneuropathy ...
Olesya Kikhtyak, Khrystyna Moskva, Orysia Lishchuk   +2 more
doaj   +1 more source

MILDRONATE POTENTIAL FOR CARDIAC ARRHYTHMIA PREVENTION IN PERIOPERATIVE PERIODcardiac arrhythmias, ischemia, metabolic disturbances, cytoprotectors, antioxidants, operation-related stress, general anesthesia, Mildronate

Кардиоваскулярная терапия и профилактика, 2014
Aim. To assess the effectiveness of Mildronate in the prevention of arrhythmias during the perioperative period of open cholecystectomy under intravenous multicomponent anesthesia.Material and methods.
V. P. Mikhin, N. A. Volkova, S. A. Sumin, P. A. Eremin   +3 more
doaj   +1 more source

Mildronate as a Regulator of Protein Expression in a Rat Model of Parkinson’s Disease

Medicina, 2011
Background. Mildronate (3-[2,2,2-trimethylhydrazinium] propionate dihydrate) traditionally is a well-known cardioprotective drug. However, our recent studies convincingly demonstrated its neuroprotective properties. The aim of the present study was to evaluate the influence of mildronate on the expression of proteins that are involved in the ...
Isajevs, Sergejs, Isajeva, Darja, Beitnere, Ulrika, Jansone, Baiba, Kalvinsh, Ivars, Klusa, Vija   +5 more
openaire   +2 more sources

INFLUENCE OF MILDRONATE ON EFFICIENCY OF ANTIANGINAL THERAPY IN PATIENTS WITH STABLE BURDEN ANGINA

Рациональная фармакотерапия в кардиологии, 2015
Aim. To study influence of mildronate (M) on treatment efficiency of patients with ischemic heart disease (IHD), receiving standard antianginal therapy (AAT)Materials and methods.
N. P. Kutishenko, N. A. Dmitrieva, Y. V. Lukina, M. P. Kozireva, Y. E. Semyonova, A. D. Deev, S. Y. Martsevich   +6 more
doaj   +1 more source

Analysis of mildronate effect on the catalytic activity of cytochrome Р450 3А4

Bulletin of Russian State Medical University, 2016
In this work, we have studied the effect of mildronate on the catalytic properties of cytochrome Р450 3А4. The analysis of the catalytic activity was carried out using electrochemical methods, with cytochrome Р450 3А4 immobilized on the electrode surface. In the presence of 50 μM mildronate, no increase was observed in the turnover number of cytochrome
KUZIKOV A.V., BULKO T.V., MASAMREKH R.A., MAKHOVA A.A., ARCHAKOV A.I., USANOV S.A., SHIKH E.V., SHUMYANTSEVA V.V.   +7 more
openaire   +3 more sources

MILDRONATE POTENTIAL FOR CORRECTING COGNITIVE DYSFUNCTION IN ELDERLY PATIENTS WITH ARTERIAL HYPERTENSION

Российский кардиологический журнал, 2011
The study aimed to assess the effects of long-term and course mildronate therapy (500 mg/d) on cognitive function in elderly patients with arterial hypertension (AH) and cognitive dysfunction.
M. E. Statsenko, S. V. Nedogoda, S. V. Turkina, I. A. Tyshchenko, L. V. Poletaeva, E. V. Chumachok, A. A. Ledyaeva, V. V. Tsoma   +7 more
doaj  

MILDRONATE POTENTIAL IN PATIENTS WITH CARDIOVASCULAR DISEASE

Российский кардиологический журнал, 2010
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V. P. Mikhin, F. E. Khlebodarov
openaire   +1 more source