Results 41 to 50 of about 624 (180)

COMPARATIVE EFFECTIVENESS OF CARDIOCYTE PROTECTORS IN COMPLEX MANAGEMENT OF ARTERIAL HYPERTENSION

Российский кардиологический журнал, 2009
The study investigated the effects of cardiocyte protectors, mexicor and mildronate, in combination with ACE inhibitors, on blood levels of lipid peroxidation products, vascular endothelial function, circadian profile of blood pressure, and left ...
F. E. Khlebodarov, V. P. Mikhin, A. V. Gorlova   +2 more
doaj  

EFFECT OF CYTOPROTECTION ON THE OXIDATIVE PROCESSES AND ENDOTHELIAL FUNCTION IN ELDERLY PATIENTS WITH ISCHEMIC HEART DISEASE

Рациональная фармакотерапия в кардиологии, 2016
Aim. To investigate the effects of cytoprotection with mildronate (Grindex, Latvia) on oxidative processes and endothelial function in elderly patients with ischemic heart disease (IHD). Material and methods.
A. V. Shabalin, Yu. I. Ragino, S. A. Lyubimtseva, Ya. V. Polonskaya, M. V. Ivanova   +4 more
doaj   +1 more source

The Cardioprotective Effect of Mildronate is Diminished After Co-Treatment With l-Carnitine

, 2011
Mildronate, an inhibitor of l-carnitine biosynthesis and uptake, is a cardioprotective drug whose mechanism of action is thought to rely on the changes in concentration of l-carnitine in heart tissue.
Helena Cirule, Osvalds Pugovics, Janis Kuka, Ivars Kalvinsh, Reinis Vilskersts, Edgars Liepinsh, Marina Makrecka, Maija Dambrova   +7 more
core   +1 more source

INFLUENCE OF MILDRONATE ON EFFICIENCY OF ANTIANGINAL THERAPY IN PATIENTS WITH STABLE BURDEN ANGINA

Рациональная фармакотерапия в кардиологии, 2015
Aim. To study influence of mildronate (M) on treatment efficiency of patients with ischemic heart disease (IHD), receiving standard antianginal therapy (AAT)Materials and methods.
N. P. Kutishenko, N. A. Dmitrieva, Y. V. Lukina, M. P. Kozireva, Y. E. Semyonova, A. D. Deev, S. Y. Martsevich   +6 more
doaj   +1 more source

EFFECTS OF TRIMETHYLAMINE-N-OXIDE INHIBITOR IN COMBINATION WITH ANTICHOLINESTERASE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Proceedings of the Shevchenko Scientific Society: Medical Sciences, 2018
Aim. Assessment of Ipigrix effectiveness (patented name of Ipidacrine) taking as a self-administered and in combination with Mildronate (patented name of Meltedonium) in patients with type 2 diabetes mellitus suffering from diabetic polyneuropathy ...
Olesya Kikhtyak, Khrystyna Moskva, Orysia Lishchuk   +2 more
doaj   +1 more source

Investigation of protective activity of mildronate in diabetes related models of cardiovascular diseases [PDF]

, 2009
Mildronāta protektīvās aktivitātes izpēte ar diabētu saistīto kardiovaskulāro slimību modeļos Anotācija Otrā tipa cukura diabēts ir slimība, kam raksturīgi glikozes un lipīdu metabolisma traucējumi. Pacientiem ar 2.
Reinis Vilšķērsts, Vilšķērsts, Reinis   +1 more
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Analysis of mildronate effect on the catalytic activity of cytochrome Р450 3А4

Bulletin of Russian State Medical University, 2016
In this work, we have studied the effect of mildronate on the catalytic properties of cytochrome Р450 3А4. The analysis of the catalytic activity was carried out using electrochemical methods, with cytochrome Р450 3А4 immobilized on the electrode surface. In the presence of 50 μM mildronate, no increase was observed in the turnover number of cytochrome
KUZIKOV A.V., BULKO T.V., MASAMREKH R.A., MAKHOVA A.A., ARCHAKOV A.I., USANOV S.A., SHIKH E.V., SHUMYANTSEVA V.V.   +7 more
openaire   +3 more sources

The change of the concomitant systems of POL, AOS and hemostasis in vascular complications forming under the experimental diabetes mellitus and their antioxidant correction

RUDN Journal of Medicine, 2009
In ESD experimental diabetes mellitus on the background of vitamin E and mildronate introduction, an activation of amino acid system: SOD and catalaza and decrease of MDA content in erythrocytes.
S G Dzugkoev, L G Khetagurova, F S Dzugkoeva   +2 more
doaj  

Protective effects of mildronate in indinavir- and efavirenz-induced toxicity in mice

, 2010
Protective effects of mildronate in indinavir- and efavirenz-induced toxicity in mice Previously we showed that mildronate effectively protected mice heart tissue against the toxic influence of anti-HIV drugs azidothymidine, stavudine and ...
Jolanta Pupure, Ivars Kalviņš, Vija Kluša, Sergejs Isajevs   +3 more
core   +1 more source

Mildronate affect on memory processes in the passive avoidance test in rats

, 2010
Daudzām neirodeģeneratīvām saslimšanām ir raksturīgi atmiņas traucējumi, kas ietver neironu struktūras vai funkciju zudumu, mitohondriju difunkciju, šūnu nāvi, oksidatīvo stresu.
Liepniece, Antra
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