New views of mildronate use for the prevention and correction of impairment of adaptive processes
Protective and normalizing mildronate action on the level of non enzyme kation proteins in the neurophils and contents of kateholamins in erythrocytes were revealed on the experimental model of the emotional-pain stress.
L V Logunova
doaj
Effects of mildronate in experimental model of ischemic brain damage in vivo
Mildronāts (3-(2,2,2-trimetilhidrazīna propionāta dihidrāts) ir L-karnitīna biosintēzes inhibitors un antiišēmisks medikaments. Šī darba mērķis bija noskaidrot mildronāta terapijas ietekmi pēc-insulta periodā, novērtējot motoro, sensorimotoro un ...
Ošeniece, Baiba
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Microencapsulation of Mildronate in Biodegradable and Non- Biodegradable Polymers
The extremely high hygroscopicity (solubility in water ≥2 g/ml) of the pharmaceutical preparation mildronate defines specific requirements to both packaging material and storage conditions.
Sokolova, Marina +6 more
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PHARMACEUTICAL CORRECTION OF VASCULAR DISTURBANCES IN PATIENTS WITH ARTERIAL HYPERTENSION
Aim: To study vascular stiffness and elasticity, microcirculation (MC) parameters, and mildronate effects in patients with arterial hypertension (AH). Material and methods.
L. A. Khaisheva +4 more
doaj
Comparative effectiveness of myocardial cytoprotectors in chronic heart failure treatment
The study is focused on comparative effectiveness of myocardial cytoprotectors in chronic heart failure (CHF) treatment. In total, 120 patients with Functional Class (FC) II-III CHF were divided into two groups.
G. G. Semenkova, L. V. Kokoreva
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Role of Carnitine palmitoiltransferase-1 in mechanisms of action of mildronate
Mildronāts ir zāļu viela, kas samazina karnitīna koncentrāciju audos, kavējot karnitīna biosintēzi un samazinot tā reabsorbciju nierēs. Karnitīns piedalās garķēžu taukskābju enerģijas metabolismā.
Homka, Aija
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Mildronate effect on lipid metabolism in experimetal type 1 diabetes
Mildronāts ietekmē toksisko starpproduktu uzkrāšanos išēmiskajos audos, kuri radušies β – oksidācijas procesā, tā pasargājot audus no oksidatīvā stresa.
Žengele, Jolanta
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Altered Blood Molecular Markers of Cardiovascular Function in Rats after Intrauterine Hypoxia and Drug Therapy. [PDF]
Popazova O +4 more
europepmc +1 more source
Introduction: Currently, chronic heart failure (CHF) is one of the leading problems of modern healthcare. Its most common manifestation is the deterioration of the inotropic reserves of the heart muscle, which over time leads to decompensation and damage
Valentin Kataev +8 more
doaj +1 more source
Cardioprotective Activity of Pharmacological Agents Affecting NO Production and Bioavailability in the Early Postnatal Period after Intrauterine Hypoxia in Rats. [PDF]
Popazova O +5 more
europepmc +1 more source

