Results 61 to 70 of about 354 (165)

Cardioprotective effect of hydroxybenzoic acid ester containing neuroactive acid, compound F-26, in conditions of isoproterenol heart failure in rats

Research Results in Pharmacology
Introduction: Currently, chronic heart failure (CHF) is one of the leading problems of modern healthcare. Its most common manifestation is the deterioration of the inotropic reserves of the heart muscle, which over time leads to decompensation and damage
Valentin Kataev, Valentina N. Perfilova, Igor I. Prokofiev, Alla A. Nesterova, Julia K. Isaeva, Margarita V. Kustova, Ivan N. Tyurenkov, Anatoly K. Brel, Valeriy A. Kataev   +8 more
doaj   +1 more source

CYTOPROTECTOR MILDRONATE IN CORRECTING MYOCARDIAL DYSFUNCTION AMONG STABLE ANGINA PATIENTS AFTER CORONARY REVASCULARISATION

Российский кардиологический журнал, 2009
In total, 149 patients, aged 41–75 years, with Functional Class (FC) II-III stable angina, who underwent coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI), were examined.
I. G. Gordeev, E. E. Luchinkina, S. V. Hegay   +2 more
doaj  

Solid herbal extract of Primula veris L. improves morphofunctional condition of rats' myocardium in chronic alcohol intoxication. [PDF]

J Tradit Complement Med, 2023
Prokofiev II, Kustova MV, Nesterova AA, Perfilova VN, Khusainova GH, Borodkina LE, Tivon YV, Tyurenkov IN, Kataev VA, Latypova GM.   +9 more
europepmc   +1 more source

Unlocking the Potential of Meldonium: From Performance Enhancement to Therapeutic Insights

Psychoactives
Meldonium, a promising pharmacological agent initially developed for cardiovascular indications, has sparked considerable interest in recent years due to its potential performance-enhancing effects.
Val Bellman
doaj   +1 more source

Inhibition of mitochondrial fatty acid β-oxidation activates mTORC1 pathway and protein synthesis via Gcn5-dependent acetylation of Raptor in zebrafish. [PDF]

J Biol Chem, 2023
Zhou WH, Luo Y, Li RX, Degrace P, Jourdan T, Qiao F, Chen LQ, Zhang ML, Du ZY.   +8 more
europepmc   +1 more source

MAIN THERAPEUTIC PRINCIPLES IN PREMENOPAUSAL WOMEN

Российский кардиологический журнал, 2011
The review outlines the main mechanisms of protective estrogen effects on cardiovascular system and the role of estrogen deficiency in cardiovascular disease (CVD) development. The position of the International Menopause Society (2009) on CVD in women is
S. N. Tolstov, I. A. Salov, V. B. Mychka, M. Yu. Kirillova, N. A. Voychenko, I. V. Kuznetsova   +5 more
doaj  

Mildronate (meldonium): First, do no harm

, 2020
Meldonium (Mildronate) is used as a cardioprotective drug; however, it has not been officially approved anywhere outside the former Soviet Union (SU). The supposed action mechanism is based on the carnitine (Lcarnitine) lowering effect in muscular and cardiac tissues.
openaire   +1 more source

EFFECTS OF MILDRONATE, AS A PART OF COMBINED HEART FAILURE THERAPY, ON CARBOHYDRATE AND LIPID METABOLISM AND OXIDATIVE STRESS PARAMETERS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Российский кардиологический журнал, 2010
In total, 100 patients aged 45-70 years, with Functional Class (FC) II-III chronic heart failure (CHF) and compensated or sub-compensated Type 2 diabetes mellitus (DM-2) were examined.
M. E. Statsenko, S. V. Turkina, S. V. Belenkova, L. V. Poletaeva, G. P. Dudchenko   +4 more
doaj  

Lipid peroxidation and protective antioxidant systems in coronary bypass surgery and cardioprotective therapy

Российский кардиологический журнал, 2005
Оn-pump coronary bypass surgery was performed in 58 stable angina patients aged 43-72. Group I (n = 19) received standard coronary heart disease (CHD) treatment, together with mildronate: before the surgery, 750 mg/d for 3 days, then 750 mg/d twice a ...
I. G. Gordeev, E. E. Ilina, V. A. Lusov, N. A. Volov, E. A. Bekchiu, A. Yu. Lebedeva   +5 more
doaj  

CRIP1 suppresses BBOX1-mediated carnitine metabolism to promote stemness in hepatocellular carcinoma. [PDF]

EMBO J, 2022
Wang J, Zhou Y, Zhang D, Zhao W, Lu Y, Liu C, Lin W, Zhang Y, Chen K, Wang H, Zhao L.   +10 more
europepmc   +1 more source