Results 21 to 30 of about 624 (180)
TRIMETAZIDINE AND MILDRONATE AS DIRECT ACTION Β2 - ADRENOSENSIBILIZERS (EXPERIMENTAL EVIDENCE)
Trimetazidine and mildronate as direct action β2 - adrenosensibilizers (experimental evidence).
V. I. Tsirkin +6 more
doaj +1 more source
Mildronate and its Neuroregulatory Mechanisms: Targeting the Mitochondria, Neuroinflammation, and Protein Expression [PDF]
This review for the first time summarizes the data obtained in the neuropharmacological studies of mildronate, a drug previously known as a cardioprotective agent.
Ivars Kalvinsh +14 more
core +3 more sources
Aim. To assess the effectiveness of Mildronate in the prevention of arrhythmias during the perioperative period of open cholecystectomy under intravenous multicomponent anesthesia.Material and methods.
V. P. Mikhin +3 more
doaj +2 more sources
The study aimed to assess the effects of long-term and course mildronate therapy (500 mg/d) on cognitive function in elderly patients with arterial hypertension (AH) and cognitive dysfunction.
M. E. Statsenko +7 more
doaj +1 more source
Mildronate (meldonium): First, do no harm
Meldonium (Mildronate) is used as a cardioprotective drug; however, it has not been officially approved anywhere outside the former Soviet Union (SU). The supposed action mechanism is based on the carnitine (Lcarnitine) lowering effect in muscular and ...
Jargin S.V.
core +2 more sources
New views of mildronate use for the prevention and correction of impairment of adaptive processes
Protective and normalizing mildronate action on the level of non enzyme kation proteins in the neurophils and contents of kateholamins in erythrocytes were revealed on the experimental model of the emotional-pain stress.
L V Logunova
doaj +1 more source
In total, 149 patients, aged 41–75 years, with Functional Class (FC) II-III stable angina, who underwent coronary artery bypass graft surgery (CABG) or percutaneous coronary intervention (PCI), were examined.
I. G. Gordeev +2 more
doaj +1 more source
Mildronate. Chronic fatigue syndrome
Chronic fatigue syndrome (CFS) is a state of constant, impairing quality of life, fatigue, lasting more than 6 months, inexplicable by any of coexisting patient’s pathological conditions. The prevalence of CFS in the world is approximately 2 % of the population (120–140 mln inhabitants of Earth). The etiology of CFS is unknown.
A. V. Filippova +3 more
openaire +2 more sources
To assess the influence of a metabolic agent, mildronate, on endothelial function in chronic heart failure (CHF) with normal systolic function, 105 patients with I-IIA Stage, II-III Functional Class (FC) CHF, and normal left ventricular systolic function,
V. P. Geychenko +2 more
doaj +1 more source
In total, 60 45-70-year-old patients with Functional Class II-III chronic heart failure (CHF) after a myocardial infarction, compensated or sub-compensated Type 2 diabetes mellitus (DM-2), and autonomous cardiac neuropathy were examined.
M. E. Statsenko +2 more
doaj +1 more source

