Results 241 to 250 of about 2,684,742 (388)

Effects of maternal allergy and supplementation with ω-3 fatty acid and probiotic on human milk oligosaccharides. [PDF]

open access: yesPediatr Allergy Immunol
Al-Kaabawi A   +6 more
europepmc   +1 more source

Branched‐Chain α Keto‐Acid Dehydrogenase Kinase‐Mediated AKT Phosphorylation Promotes RCC Tumorigenesis and Drug Resistance

open access: yesAdvanced Science, EarlyView.
This study identifies a novel oncogenic role and a previously unrecognized phosphorylation substrate of BCKDK in RCC, wherein it promotes tumor progression and drug resistance through AKT phosphorylation at both Thr308 and Ser473 sites and activation of AKT/mTOR and AKT/ABCB1 signaling pathways, offering a promising prognostic marker and therapeutic ...
Qin Tian   +18 more
wiley   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

open access: yesAdvanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu   +10 more
wiley   +1 more source

Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD

open access: yesAdvanced Science, EarlyView.
TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang   +9 more
wiley   +1 more source

Correction: New latex agglutination assay for the determination of lactoferrin in human milk

open access: yesInternational Breastfeeding Journal
Miori Tanaka   +2 more
doaj   +1 more source

An Inexpensive AI-Powered IoT Sensor for Continuous Farm-to-Factory Milk Quality Monitoring. [PDF]

open access: yesSensors (Basel)
Fizza K   +5 more
europepmc   +1 more source

CARBONIC ACID AND CARBONATES IN COW'S MILK

open access: hybrid, 1919
L. L. Van Slyke, John C. Baker
openalex   +1 more source

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