Results 71 to 80 of about 586,800 (361)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

open access: yesFEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel   +9 more
wiley   +1 more source

Composition of major proteins in cow milk differing in mean protein concentration during the first 155 days of lactation and the influence of season as well as short-term restricted feeding in early and mid-lactation

open access: yesCzech Journal of Animal Science, 2014
A variety of proteins contributes greatly to the unique nutritional and functional quality of dairy cow milk. Particularly, milk casein content and composition have substantial influence on the processing capabilities.
K. Gellrich, H.H.D. Meyer, S. Wiedemann
doaj   +1 more source

Effect of supplementary glycerin on milk composition and heat stability in dairy goats [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2017
Objective This experiment was studied the effects of various levels of crude glycerin (CG) in dairy goat diet on daily intake, milk yield, milk composition, some physical properties and some quality changes of goat milk after sterilization.
Deela Thoh   +2 more
doaj   +1 more source

Potentials to differentiate milk composition by different feeding strategies [PDF]

open access: yes, 2009
To investigate the effect of the dietary intake of the cow on milk composition, bulk-tank milk was collected on 5 occasions from conventional (n = 15) and organic (n = 10) farms in Denmark and on 4 occasions from low-input nonorganic farms in the United ...
Butler, G.   +5 more
core   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

open access: yesFEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez   +5 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Covariance among milking frequency, milk yield, and milk composition from automatically milked cows

open access: yesJournal of Dairy Science, 2011
Automatic milking systems allow cows voluntary access to milking and concentrates within set limits. This leads to large variation in milking intervals, both within and between cows, which further affects yield per milking and composition of milk. This study aimed to describe the degree to which differences in milking interval were attributable to ...
Løvendahl, Peter, Chagunda, G G
openaire   +4 more sources

Multivariate analysis relating milk production, milk composition, and seasons of the year

open access: yesAnais da Academia Brasileira de Ciências
Our objective was to quantify the relationship between seasons of the year, milk production, and milk composition of a dairy farm based on data for 48 consecutive months, using multivariate statistical analyses.
IONE M.P. HAYGERT-VELHO   +8 more
doaj   +1 more source

A genetic and economic evaluation of lactose in the New Zealand dairy industry : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science [PDF]

open access: yes, 2016
Milk composition in New Zealand is heavily influenced by the selection for Breeding Worth (BW) and the breed composition of the national herd. Under selection for BW a greater emphasis is placed upon protein (39% of emphasis) than fat yield (13% of ...
Sneddon, Nicholas William
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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