Results 131 to 140 of about 54,620 (290)
ABSTRACT Gastrointestinal conditions such as irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD) are characterized by alterations in physiological and immune functions. Given the circadian clock influences gastrointestinal physiology and immunity, we hypothesized that the peripheral circadian clock is altered in these patients and ...
Sophie Fowler +12 more
wiley +1 more source
After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens ...
Feng, X. +7 more
core +1 more source
Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang +16 more
wiley +1 more source
Egg and cows' milk hypersensitivity in exclusively breast fed infants with eczema, and detection of egg protein in breast milk. [PDF]
A J Cant, R.A. Marsden, Peter J. Kilshaw
openalex +1 more source
Exploring the relationship between dietary patterns, eating behaviour and fat taste detection thresholds : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Nutrition and Dietetics at Massey University, Albany, New Zealand [PDF]
Background: Dietary pattern analysis provides a unique opportunity to explore combinations of food intake in conjunction with factors known to affect dietary intake. Fat taste sensitivity is an emerging correlate of dietary intake and, when impaired, has
Henderson, Lisa
core
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan +9 more
wiley +1 more source
Knowledge about occupational latex allergy amongst Thai nurses and student nurses. [PDF]
De Vocht, Frank +2 more
core +1 more source
This study demonstrates that PACAP alleviates paclitaxel‐induced peripheral neuropathy in mice. Its protective mechanism involves activating the PGC‐1α pathway to restore mitochondrial function and reduce oxidative stress in sensory neurons. Crucially, PACAP does not interfere with the anti‐tumor efficacy of paclitaxel.
Ruyue Mo +8 more
wiley +1 more source
ABSTRACT Background and Aim Coffee after digestive surgery is a simple, safe, and inexpensive prevention for post‐operative ileus (POI). Several meta‐analyses have shown that coffee consumption in the post‐operative period may enhance bowel recovery. However, uptake in clinical routine is variable, standardization challenging and compliance unknown. We
Constant Delabays +4 more
wiley +1 more source
Herbal folk remedies for animal health in the Netherlands [PDF]
As a part of their training in herbalism 85 students of the two private schools for natural animal care that exist in the Netherlands were given the assignment to ask farmers, pet owners and animal pension keepers about their traditional remedies.
Beijer, Helen, Van Asseldonk, Drs. Tedje
core

