Results 51 to 60 of about 53,023 (283)

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Clinical Presentations of IgE-Mediated Cow’s Milk Allergy in Children and Factors Affecting the Development of Tolerance

Güncel Pediatri
Introduction: Food allergies are responses triggered by various immunological mechanisms to foods or additives, manifesting through IgE, non-IgE or mixed-type reactions.
Ughur Zeynallı, Muhammed Fatih Erbay, Şefika İlknur Kökçü Karadağ, Deniz Özçeker   +3 more
doaj   +1 more source

Food as a trigger for abdominal angioedema attacks in patients with hereditary angioedema

Orphanet Journal of Rare Diseases, 2018
Background Hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE) is a rare inherited disease. In most HAE-affected subjects, defined trigger factors precede angioedema attacks.
Urs C. Steiner, Lea Kölliker, Christina Weber-Chrysochoou, Peter Schmid-Grendelmeier, Elsbeth Probst, Walter A. Wuillemin, Arthur Helbling   +6 more
doaj   +1 more source

Correlation between cow’s milk protein allergy and otitis media: a systematic review

Brazilian Journal of Otorhinolaryngology, 2022
Objectives: To review the evidence pertaining to the association between cow’s milk protein allergy and recurrent acute otitis media and otitis media with effusion.
Karen Amanda Soares de Oliveira, Marina Tomaz Esper, Morgana Lívia de Oliveira, Marise Helena Cardoso Tofoli, Melissa Ameloti Gomes Avelino   +4 more
doaj   +1 more source

An Inflammation‐Targeting Engineered Probiotic Escherichia coli Nissle 1917 with High Anti‐TNF‐α Nanobody Secretion Efficacy Alleviates Ulcerative Colitis

Advanced Science, EarlyView.
Ulcerative colitis therapy requires precise drug targeting. This study engineers a probiotic E. coli Nissle 1917 to surface‐display ANXA5, enabling specific binding to phosphatidylserine (PS) exposed on inflamed colonic epithelium for enhanced targeting and colonization.
Siqi Hua, Kaiqiang Li, Pengyou Shang, Lina Liu, Jiayu Pan, Bo Zhu, Zichun Hua   +6 more
wiley   +1 more source

The baked side: Cow's milk and egg protein threshold dose distributions in children reacting to baked milk and baked egg

World Allergy Organization Journal
Background: Children allergic to milk and egg, but tolerant to baked products, display higher reactivity thresholds than the general population of children allergic to milk and egg.
Rocco Luigi Valluzzi, MD, Carla Riccardi, MD, Sara Urbani, MD, Davide Ursi, MD, Deborah Zavettieri, MD, Francesco Di Girolamo, PhD, Lamia Dahdah, MD, Veronica Calandrelli, PharmD, Vincenzo Fierro, MD, Alessandro Fiocchi, MD   +9 more
doaj   +1 more source

Trans-epithelial immune cell transfer during suckling modulates delayed-type hypersensitivity in recipients as a function of gender. [PDF]

PLoS ONE, 2008
INTRODUCTION: Breast feeding has long term effects on the developing immune system which outlive passive immunization of the neonate. We have investigated the transfer of milk immune cells and examined the result of transfer once the recipients were ...
Lisa J Ma, Barbara Walter, Ariel Deguzman, H Konrad Muller, Ameae M Walker   +4 more
doaj   +1 more source

Evaluation of the complementary feeding practices, dietary intake, and nutritional status of infants on a cow's milk protein elimination diet

Jornal de Pediatria, 2022
Objective: To evaluate the complementary feeding practices, food intake, and nutritional status of infants on a cow's milk protein elimination diet. Methods: A cross-sectional and observational study was conducted to compare infants aged 4–18 months who ...
Juliana Frizzo, Vanessa C.C. Rodrigues, Patrícia G.L. Speridião, Mauro B. Morais   +3 more
doaj   +1 more source

The cumulative analgesic effect of repeated electroacupuncture is modulated by Adora3 in the SCDH of mice with neuropathic pain

Animal Models and Experimental Medicine, EarlyView.
Neuropathic pain management via repeated electroacupuncture. Abstract Background Existing remedial approaches for relieving neuropathic pain (NPP) are challenging and open the way for alternative therapeutic measures such as electroacupuncture (EA). The mechanism underlying the antinociceptive effects of repeated EA sessions, particularly concerning ...
Faisal Ayub Kiani, Hao Li, Panpan Guo, Qiulin Zhang, Mahmoud M. Abouelfetouh, Mingxing Ding, Yi Ding   +6 more
wiley   +1 more source

Food allergies in pregnant women: a study of prevalence in expecting mothers and association with neonatal outcomes [PDF]

, 2013
Thesis (M.A.)--Boston UniversityIntroduction: Food allergies, the second most common form of allergic disorders in Western countries, have been on the rise in the US over the past few decades especially in young children.
Seita, Helene M.
core   +1 more source