Results 41 to 50 of about 99,581 (256)

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

Advanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang, Zhisheng Xu, Yaou Duan, Yehui Sun, Shiying Wu, Tao Long, Mateusz Durbacz, Li Zhang, Yufen Xiao, Yu‐Chung Pien, Erick D. Guerrero, Zeru Tian, Xu Wang, Pratima Basak, Sumanta Chatterjee, Ning Liu, Xiaochun Li, Eric N. Olson, Daniel J. Siegwart   +18 more
wiley   +1 more source

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

HS-SPME-GC-MS Analysis of Volatile Compounds in Whole-Fat Cow and Goat Milk Powder during Accelerated Oxidation [PDF]

Shipin Kexue
In order to investigate the changes of flavor substances in whole-fat cow and goat milk powder during storage, the volatile compounds of whole-fat cow and goat milk powder during accelerated oxidation were analyzed using headspace solid-phase ...
XUE Haiyan, LI Xinyu, MENG Yi, HE Baoyuan, ZHANG Lei, LIU Xiaofeng, MA Jun
doaj   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

RESPON IMUN MUKOSA DAN SELULER PADA TIKUS YANG DIBERI BUBUK SUSU KAMBING DENGAN INFEKSI Salmonella Typhimurium [Mucosal and Cellular Immune Response of Rat Given Goat Milk Powder and Infected with Salmonella Typhimurium]

Jurnal Teknologi dan Industri Pangan, 2013
Goat milk contains bioactive proteins and oligosaccharides which can act as immunomodulators and prebiotics respectively. The objectives of this study were to determine the effect of giving goat milk powder on mucosal immune response (sIgA/secretory ...
Eni Harmayani3), Madarina Julia2), Nurliyani1)*, Endang Baliarti1)   +3 more
doaj   +1 more source

Physicochemical Properties and Whey Proteomes of Camel Milk Powders Produced by Different Concentration and Dehydration Processes

Foods, 2022
Camel milk powder production is an alternative to preserve the perishable milk for later-date consumption. However, the impacts of dehydration processes on bioactive compounds in camel milk are largely unknown.
Zhengzheng Zou, John A. Duley, David M. Cowley, Sarah Reed, Buddhika J. Arachchige, Bhesh Bhandari, Paul N. Shaw, Nidhi Bansal   +7 more
doaj   +1 more source

Directional Confinement Governed Ion Transport for Efficient Actuation

Advanced Materials, EarlyView.
Structural anisotropy provides an effective means to regulate ion transport in polymer electrolytes. Directionally aligned channels formed by freeze‐drying provide continuous pathways for ion migration, enhancing ion mobility and simultaneously improving the strain and blocking force of ionic actuators.
Yufei Zhang, Qiuchun Lu, Adit Gupta, Sen Wang, Xueyang Wang, Jian Yu, Xuanyi Hu, Daniel Mandler, Pooi See Lee   +8 more
wiley   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

Effects of feeding infant formula rich in sn-2 palmitate for 6 months on fecal saponified fatty acids, calcium and stool characteristics: a cluster-randomized controlled trial

Nutrition Journal
Background Human milk palmitic acid (PA) is mainly esterified at the sn-2 position of triacylglycerols, while infant formula contains palmitate predominantly in the sn-1/3 positions.
Qianqian Shen, Wei Wu, Ai Zhao, Sha Luo, Yanjie Hao, Hua Jiang, Tingchao He, Biao Liu, Wenhui Ye, Yumei Zhang   +9 more
doaj   +1 more source

Preparation and Quality Analysis of Lentinula edodes Flavored Milk Tablets

Shipin gongye ke-ji, 2022
Using fresh Lentinus edodes and milk powder as the main materials, the Lentinus edodes flavored milk tablets was prepared through processes such as mixing, granulating, drying, granulating and tableting.
Liucheng GUO, Liyue DU, Fei WANG
doaj   +1 more source