Results 61 to 70 of about 27,275 (257)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Pengaruh penggunaan ajitein dalam pakan terhadap produksi dan kualitas susu sapi perah

Jurnal Ilmu-Ilmu Peternakan, 2014
The aim of this research was to know the effect of ajitein supplementation as protein source in the ration of dairy cow lactation on milk production and quality. The materials in this research were twelve dairy cows (Friesian Holstein crossbreed).
K. P. W. Sunu, Hartutik Hartutik, Hermanto Hermanto   +2 more
doaj  

Justification of unconventional protein-containing raw materials for the construction of milk chocolate formulas with increased biological value

Vestnik MGTU, 2020
Milk chocolate is particularly popular with different age groups. It is characterized by low protein content with a large amount of fats and carbohydrates determining the food imbalance of the product.
Linovskaya N. V., Mazukabzova E. V., Rudenko O. S. , Savenkova T. V.   +3 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Changes in milk performance and hepatic metabolism in mid-lactating dairy goats after being fed a high concentrate diet for 10 weeks

Animal, 2017
Feeding a high concentrate (HC) diet is a widely used strategy for supporting high milk yields, yet it may cause certain metabolic disorders. This study aimed to investigate the changes in milk production and hepatic metabolism in goats fed different ...
H.B. Dong, L.L. Sun, R.H. Cong, S.Y. Tao, Y.Q. DuanMu, J. Tian, Y.D. Ni, R.Q. Zhao   +7 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Ratio of Native Grass and Concentrate in the Ration to the Quality of Milk Production of Holstein Cow

Animal Production: Indonesian Journal of Animal Production, 2005
The research attempted to find out ratio of native grass and concentrate in the ration to the quality of milk production of Holstein cow. Latin Square Design was used with five treatments of ratio of native grass and concentrate ( 70 : 30%, 60 : 40%, 50 :
Dadang Suherman
doaj  

The effect of concentrate crude protein concentration and replacing imported feed ingredients with locally grown cereals and faba bean on milk production and nitrogen utilization in grazing dairy cows

Journal of Dairy Science
: Concentrate feeds with a lower CP concentration are an effective means of reducing nitrogen (N) excretion from grazing dairy cows. Typically, imported feedstuffs such as soybean meal and maize are included in concentrate feeds to increase the protein ...
K.M. McCarthy, K.M. Pierce, Z.C. McKay, A.G. Fahey, N.A. Walsh, N. Ryan, M. McDonald, A. Ryan, M. Markiewicz-Keszycka, F.J. Mulligan   +9 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Effect of whey protein concentrate on the quality characteristics and yield of cottage cheese

Современная наука и инновации
Introduction. The lack of protein in the human diet is a problem faced by the population of many countries around the world. An effective solution is the use of protein supplements, including whey protein concentrate (WPC), in the production of dairy ...
E. Y. Porotova, M. V. Kaledina
doaj   +1 more source