Results 81 to 90 of about 27,275 (257)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Comparison of part-time grazing and indoor silage feeding on milk production

open access: yesAgricultural and Food Science, 2008
Cows were assigned randomly to indoor silage feeding (with 2 h outdoor exercise) or part-time grazing treatment in two different experiments. One group was kept in confinement with ad libitum grass silage within each experiment.
A. SAIRANEN, H. KHALILI, P. VIRKAJÄRVI
doaj  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Concentrate supplementation during dry season enhance milk yield and quality on dromedary camel in peri urban area of Isiolo, Kenya

open access: yesVeterinary and Animal Science
Camel milk contributes 50 % of nutrients among the desert locals in Kenya. However, frequent droughts due to climate change is the major factor affecting milk production in dromedary camels.
Cyrila I. Lusala   +3 more
doaj   +1 more source

Coagulation of uf concentrated milk 1. influence of protein concentration, milk heat treatment

open access: yes, 2003
U radu je, pomoću dinamičkih merenja, metodom kontinuelnih oscilacija proučavan tok koagulacije mleka koncentrovanog ultrafiltracijom, u zavisnosti od stepena koncentrovanja mleka i režima njegove termičke obrade. Uticaj termičke obrade mleka obuhvatio je praćenje četiri režima termičke obrade mleka (A – 72°C, 15 s; B – 77°C, 120 s; C – 85°C, 120 s; i ...
Pudja, Predrag, Guinee, Timothy P.
openaire   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

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