Results 181 to 190 of about 2,360,032 (261)

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

Advanced Science, EarlyView.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang, Hongjie Gao, Bifei Zhang, Xuetian Li, Ding Li, Aihua Cao, Fengyin Sun   +6 more
wiley   +1 more source

Effects of Supplementation with Milk Proteins on Body Composition and Anthropometric Parameters: A Systematic Review and Dose-Response Meta-Analysis. [PDF]

Nutrients
Mohammadi S, Ashtary-Larky D, Alaghemand N, Alnsour AF, Shokouhifar S, Borzabadi A, Mehrbod M, Candow DG, Forbes SC, Antonio J, Suzuki K, Asbaghi O.   +11 more
europepmc   +1 more source

Effects of a Functional Ice Cream Enriched with Milk Proteins on Bone Metabolism: A Feasibility Clinical Study and In Vitro Investigation. [PDF]

Nutrients, 2023
Maurotti S, Ferro Y, Pujia R, Frosina M, Sciacqua A, Mare R, Mazza E, Geirola N, Romeo S, Pujia A, Montalcini T.   +10 more
europepmc   +1 more source

Aggregate Milk Supply Response to the Milk Income Loss Contract Program [PDF]

This research tests for changes in aggregate milk production due to the operation of the Milk Income Loss Contract (MILC) program since 2002. Aggregate production is decomposed into the size of the dairy herd and milk production per cow.
Anderson, David P., Bryant, Henry L., Outlaw, Joe L.   +2 more
core  

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

Advanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han, Jian‐sen Miao, Yi‐feng Shi, Yi‐ting Tu, Yu‐zhe Lin, Lin‐Jie Chen, Bing‐hao Lin, Hua‐lin Li, Xuan‐qi Zheng, Hong‐qiang Wu, Hai‐xiao Liu, Lei Yang, Ai‐min Wu, Zhen Lin, Jian Xiao, Gang Zheng, Chen Jin   +16 more
wiley   +1 more source

Bioactive Peptides from Milk Proteins with Antioxidant, Anti-Inflammatory, and Antihypertensive Activities. [PDF]

Foods
Borges T, Coelho P, Prudêncio C, Gomes A, Gomes P, Ferraz R.   +5 more
europepmc   +1 more source

Heat-Induced Interaction of Milk Proteins: Impact on Yoghurt Structure. [PDF]

Int J Food Sci, 2021
Asaduzzaman M, Mahomud MS, Haque ME.
europepmc   +1 more source

ALTERNATIVE FLUID MILK PROCUREMENT SYSTEMS FOR FLORIDA DAIRY FARMERS [PDF]

This article evaluates the effects of alternative fluid milk procurement strategies on the aggregate net revenue of Florida cooperative members. They are (1) supplemental milk obtained from import sources, (2) supplemental milk obtained from a supply ...
Kilmer, Richard L., Nubern, Christopher A.   +1 more
core  

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Decoding the relationship between cow's milk proteins and development of type 1 diabetes mellitus. [PDF]

Arch Endocrinol Metab
Andrade LJO, de Oliveira GCM, de Oliveira LCM, Bittencourt AMV, Baumgarth Y, de Oliveira LM.   +5 more
europepmc   +1 more source