Results 131 to 140 of about 4,915 (256)

Effects of milk replacer composition on growth and development of beef × dairy crossbred calves. [PDF]

open access: yesTransl Anim Sci
Carter RE   +5 more
europepmc   +1 more source

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen   +22 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting of difructose anhydride III (NITTEN DFA III) for female bovines, ovines, caprines in the periparturient period and neonates fed colostrum and milk/milk replacer in early life (Nippon Beet Sugar Manufacturing Co., Ltd). [PDF]

open access: yesEFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +22 more
europepmc   +1 more source

DHODH Drives Sunitinib Resistance Via a Non‐Enzymatic Mechanism by Inhibiting TRIM28 Ubiquitination and Consequent VEGFA Activation in RCC

open access: yesAdvanced Science, EarlyView.
This non‑enzymatic function of DHODH drives sunitinib resistance by competing with TRIM37 to block TRIM28 ubiquitination, thereby stabilizing TRIM28 and activating VEGFA transcription. Disrupting the DHODH–TRIM28 interaction with lisaftoclax restores drug sensitivity.
Shijie Qian   +10 more
wiley   +1 more source

Effect of Guanidinoacetic Acid Supplementation on the Performance of Calves Fed Milk Replacer. [PDF]

open access: yesAnimals (Basel)
Hazlewood KJ   +8 more
europepmc   +1 more source

Effects of Extending Milk Replacer Feeding during the Fattening Period on the Behaviour and Welfare of Lambs: A Preliminary Study. [PDF]

open access: yesAnimals (Basel), 2022
González-Martínez A   +6 more
europepmc   +1 more source

Functional Suppression of SCAP Triggers Endoplasmic Reticulum Stress‐Dependent Ferroptosis by Impairing Cholesterol Metabolism in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu   +17 more
wiley   +1 more source

Effect of partial exchange of lactose with fat in milk replacer on performance and blood metabolites of Holstein calves. [PDF]

open access: yesJDS Commun, 2023
Echeverry-Munera J   +5 more
europepmc   +1 more source

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