Results 101 to 110 of about 7,809,762 (287)
Ursa Major III/UNIONS 1: The Darkest Galaxy Ever Discovered?
The Astrophysical JournalThe recently discovered stellar system Ursa Major III/UNIONS 1 (UMa3/U1) is the faintest known Milky Way satellite to date. With a stellar mass of ${16}_{-5}^{+6}\,{M}_{\odot }$ and a half-light radius of 3 ± 1 pc, it is either the darkest galaxy ever ...
Raphaël Errani +3 more
doaj +1 more source
Advanced Science, EarlyView.This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li +15 more
wiley +1 more source
Limits on spin-dependent WIMP-proton cross-sections using the DRIFT-IId directional dark matter detector [PDF]
, 2011 The nature of dark matter remains one of the biggest questions in physics today. Weakly Interacting Massive Particles (WIMPs) are a particularly well motivated candidate for the missing matter that makes up 85% of the mass of the Universe.
Pipe, Mark
core +3 more sources
Dark matter spiral arms in Milky Way-like halos
Astronomy & AstrophysicsContext. The coupling between the dark matter (DM) halo and the stellar disc is a key factor in galactic evolution. While the interaction between structures like the Galactic bar and DM halos has been explored (e.g. slowing down of the bar due to dynamical friction), the effect of spiral arms on the DM halo distribution has received limited attention ...
Marcel Bernet +11 more
openaire +3 more sources
Novel constraints on fermionic dark matter from galactic observables I: The Milky Way [PDF]
, 2020 We have recently introduced a new model for the distribution of dark matter (DM) in galaxies based on a self-gravitating system of massive fermions at finite temperatures, the Ruffini–Argü elles–Rueda (RAR) model.
Argüelles, Carlos Raúl +3 more
core
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source
Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia
Advanced Science, EarlyView.Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li +8 more
wiley +1 more source
Challenges in Binary Pulsar Timing Detection of Dark Matter Subhalos
The Astrophysical Journal LettersRecently, binary pulsar timing has been proposed as a viable probe of dark matter subhalos with masses of ∼10 ^7 M _⊙ in the solar neighborhood.
Zheng-Long Wang +3 more
doaj +1 more source
The shape of dark matter haloes in the Aquarius simulations: Evolution and memory
EPJ Web of Conferences, 2012 We use the high resolution cosmological N-body simulations from the Aquarius project to investigate in detail the mechanisms that determine the shape of Milky Way-type dark matter haloes.
Sales L.V., Helmi A., Vera-Ciro C.A.
doaj +1 more source
Advanced Science, EarlyView.Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong +8 more
wiley +1 more source