Results 121 to 130 of about 28,645 (286)

The Milky Way Tomography with SDSS. V. Mapping the Dark Matter Halo

, 2014
We present robust constraints from the Sloan Digital Sky Survey (SDSS) on the shape and distribution of the dark matter halo within the Milky Way (MW). Using the number density distribution and kinematics of SDSS halo stars, we probe the dark matter distribution to heliocentric distances exceeding 10 kpc and galactocentric distances exceeding 20 kpc ...
Loebman, Sarah R., Ivezic, Zeljko, Quinn, Thomas R., Bovy, Jo, Christensen, Charlotte R., Juric, Mario, Roskar, Rok, Brooks, Alyson M., Governato, Fabio   +8 more
openaire   +2 more sources

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

The Milky Way's Inner Halo: Stellar Halo & Dark Matter Halo

, 2019
This presentation reviews the dynamical properties and origin of the stellar halo, and the distribution of dark matter in the inner Milky Way.
openaire   +1 more source

Engineered Carbon Dots from a Traditional Herb Pair Orchestrate Concurrent Antioxidant and AP‐1‐Mediated Inflammation to Attenuate Renal Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu, Fuying Zhu, Zhuqing Wang, Jiawen Chen, Xiaomiao Cui, Congzhong Yang, Yao Peng, Dengyuan Feng, Li Lu, Hui Wei, Xiaozhi Zhao   +10 more
wiley   +1 more source

Microlensing Optical Depth, Event Rate, and Limits on Compact Objects in Dark Matter Based on 20 Yr of OGLE Observations of the Small Magellanic Cloud

The Astrophysical Journal Supplement Series
Some previous studies have suggested that massive and intermediate-mass primordial black holes (PBHs) could comprise a substantial fraction of dark matter in the Universe.
Przemek Mróz, Andrzej Udalski, Michał K. Szymański, Igor Soszyński, Paweł Pietrukowicz, Szymon Kozłowski, Radosław Poleski, Jan Skowron, Dorota Skowron, Krzysztof Ulaczyk, Mariusz Gromadzki, Krzysztof Rybicki, Patryk Iwanek, Marcin Wrona, Milena Ratajczak   +14 more
doaj   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source

The Flattened Dark Matter Halos of NGC 4244 and the Milky Way

, 1996
10 pages, including 4 figures. Total 230 kByte. Requires the Sprocl.sty file (can be found at:http://www.wspc.co.uk) To appear in the proceedings of ``Aspects of Dark Matter in Astro- and Particle Physics'', Heidelberg, September 1996 (World Scientific: Eds. H.V. Klapdor-Kleingrothaus, Y. Ramachers)
openaire   +2 more sources

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

Cosmological Predictions for Minor Axis Stellar Density Profiles in the Inner Regions of Milky Way–mass Galaxies

The Astrophysical Journal
ΛCDM cosmology predicts the hierarchical formation of galaxies, which build up mass by merger events and accreting smaller systems. The stellar halo of the Milky Way (MW) has proven to be useful a tool for tracing this accretion history. However, most of
Madeline Lucey, Robyn E. Sanderson, Danny Horta, Aritra Kundu, Philip F. Hopkins, Arpit Arora, Jasjeev Singh, Nondh Panithanpaisal   +7 more
doaj   +1 more source

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source