Results 111 to 120 of about 28,520 (293)

Milky Way-est: Cosmological Zoom-in Simulations with Large Magellanic Cloud and Gaia–Sausage–Enceladus Analogs

The Astrophysical Journal
We present Milky Way-est, a suite of 20 cosmological cold-dark-matter-only zoom-in simulations of Milky Way (MW)-like host halos. Milky Way-est hosts are selected such that they (i) are consistent with the MW’s measured halo mass and concentration, (ii ...
Deveshi Buch, Ethan O. Nadler, Risa H. Wechsler, Yao-Yuan Mao   +3 more
doaj   +1 more source

There's no place like home? Statistics of Milky Way-mass dark matter halos

, 2009
We present an analysis of the distribution of structural properties for Milky Way-mass halos in the Millennium-II Simulation (MS-II). This simulation of structure formation within the standard LCDM cosmology contains thousands of Milky Way-mass halos and has sufficient resolution to properly resolve many subhalos per host.
Boylan-Kolchin, M., Springel, V., White, S., Jenkins, A.   +3 more
openaire   +3 more sources

miR‐185‐5p Derived From hUC‐MSC Exosomes via Suspension Culture Under Hypoxic Conditions Promotes Scarless Wound Healing in Mice by Precisely Regulating Collagen I/III Regeneration

Advanced Science, EarlyView.
miR‐185‐5p derived from UC‐MSC exosomes via hypoxic suspension culture promotes scarless wound healing in mice by precisely regulating collagen I/III regeneration. Exosomes derived from UC‐MSCs under a three‐dimensional bioreactor and hypoxic conditions were injected into the skin wounds of mice.
Lihua Yang, Yiqun Sun, Qinbiao Yan, Ali Mohsin, Kamran Ashraf, Senyi Gong, Weifeng Li, Touseef Ur Rehman, Yuwen Hu, Jinzhao He, Yu Liu, Meijun Ding, Lin Qi, Meijin Guo, Ke Xue   +14 more
wiley   +1 more source

C-19 and Hot, Wide Star Streams

The Astrophysical Journal
The C-19 star stream has the abundance characteristics of an unusually metal-poor globular cluster but kinematically is uncharacteristically hot and wide for a cluster stream, having a line-of-sight velocity dispersion of 7  ±  2 km s ^−1 and a 1 σ width
Raymond G. Carlberg, Rodrigo Ibata, Nicolas F. Martin, Else Starkenburg, David S. Aguado, Khyati Malhan, Kim Venn, Zhen Yuan   +7 more
doaj   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

The Distant Milky Way Halo from the Southern Hemisphere: Characterization of the LMC-induced Dynamical Friction Wake

The Astrophysical Journal
The infall of the Large Magellanic Cloud (LMC) into the Milky Way’s halo impacts the distribution of stars and dark matter (DM) in our Galaxy. Mapping the observational consequences of this encounter can inform us about the properties of both galaxies ...
Manuel Cavieres, Julio Chanamé, Camila Navarrete, Yasna Ordenes-Briceño, Nicolás Garavito-Camargo, Gurtina Besla, Maren Hempel, A. Katherina Vivas, Facundo Gómez   +8 more
doaj   +1 more source

Dwarf Cosmology with the Stromlo Missing Satellites Survey

Advances in Astronomy, 2010
The standard Lambda Cold Dark Matter model is considered to be a triumph of theoretical astrophysics but observations of the Milky Way and its system of satellite galaxies irresistibly signal that theory is incomplete on galactic and subgalactic scales ...
Helmut Jerjen
doaj   +1 more source

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Questioning a 3.5 keV dark matter emission line

, 2016
Context. Recent findings of line emission at 3.5 keV in both individual and stacked X-ray spectra of galaxy clusters have been speculated to have dark matter origin. Aims.
Riemer-Sorensen, Signe
core   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source