Results 61 to 70 of about 90,260 (324)

Dense gas and star formation in the outer Milky Way

Astronomy & Astrophysics, 2023
We present maps and spectra of the HCN(1−0) and HCO+(1−0) lines in the extreme outer Galaxy, at galactocentric radii between 14 and 22 kpc, with the 13.7 m Delingha telescope. The nine molecular clouds were selected from a CO/13CO survey of the outer quadrants.
Braine, J., Sun, Y., Shimajiri, Y., Van Der Tak, F. F. S., Fang, M., André, Ph, Chen, H., Gao, Y.   +7 more
openaire   +3 more sources

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

The Three-phase Evolution of the Milky Way

The Astrophysical Journal
We illustrate the formation and evolution of the Milky Way over cosmic time, utilizing a sample of 10 million red giant stars with full chemodynamical information, including metallicities and α -abundances from low-resolution Gaia XP spectra.
Vedant Chandra, Vadim A. Semenov, Hans-Walter Rix, Charlie Conroy, Ana Bonaca, Rohan P. Naidu, René Andrae, Jiadong Li, Lars Hernquist   +8 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Predicting the locations of possible long-lived low-mass first stars: Importance of satellite dwarf galaxies

, 2017
The search for metal-free stars has so far been unsuccessful, proving that if there are surviving stars from the first generation, they are rare, they have been polluted, or we have been looking in the wrong place.
Agarwal, Bhaskar, Frebel, Anna, Glover, Simon C. O., Griffen, Brendan F., Hartwig, Tilman, Klessen, Ralf S., Magg, Mattis   +6 more
core   +2 more sources

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Are galactic coronae thermally unstable?

, 2010
A substantial fraction of the baryons of disk galaxies like the Milky Way is expected to reside in coronae of gas at the virial temperature. This is the only realistic reservoir of gas available to feed star formation in the disks.
Nipoti, Carlo
core   +1 more source

DISCOVERY OF RR LYRAE STARS IN THE NUCLEAR BULGE OF THE MILKY WAY [PDF]

, 2016
Indexación: Web of ScienceGalactic nuclei, such as that of the Milky Way, are extreme regions with high stellar densities, and in most cases, the hosts of a supermassive black hole.
Gonzalez, OA, Gran, F, Minniti, D, Ramos, RC, Rejkuba, M, Valenti, E, Zoccali, M   +6 more
core   +2 more sources

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

FEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman, Annika Egeler, Saskia Rödl, Johannes M. Herrmann   +3 more
wiley   +1 more source

A Search For Star Formation in the Smith Cloud [PDF]

, 2014
Motivated by the idea that a subset of HVCs trace dark matter substructure in the Local Group, we search for signs of star formation in the Smith Cloud, a nearby ~2x10^6 Msun HVC currently falling into the Milky Way.
Baker, Ashley D., Kannappan, Sheila J., Stark, David V.   +2 more
core   +3 more sources