Results 61 to 70 of about 8,242 (260)

What Is Missing from the Local Stellar Halo?

open access: yesThe Astrophysical Journal
The Milky Way’s stellar halo, which extends to >100 kpc, encodes the evolutionary history of our Galaxy. However, most studies of the halo to date have been limited to within a few kiloparsecs of the Sun.
Katherine Sharpe   +2 more
doaj   +1 more source

Are dSph galaxies Galactic building blocks?

open access: yesEPJ Web of Conferences, 2012
Dwarf spheroidal galaxies (dSph) are frequently assumed to represent surviving examples of a vast now destroyed population of small systems in which many of the stars now forming the Milky Way were formed. Ongoing accretion and considerable sub-structure
Gilmore G., Asiri H.M.
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Mapping the Galactic Disk with the LAMOST and Gaia Red Clump Sample. VIII. Mapping the Kinematics of the Galactic Disk Using Mono-age and Mono-abundance Stellar Populations

open access: yesThe Astrophysical Journal
We present a comprehensive study of the kinematic properties of the different Galactic disk populations, as defined by the chemical abundance ratios and stellar ages, across a large disk volume (4.5 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc), by using the ...
Weixiang Sun   +7 more
doaj   +1 more source

The formation history of the Milky Way disc with high-resolution cosmological simulations [PDF]

open access: green, 2021
Marco Giammaria   +5 more
openalex   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Accurate, Precise, and Physically Self-consistent Ages and Metallicities for 400,000 Solar Neighborhood Subgiant Branch Stars

open access: yesThe Astrophysical Journal
Age is the most difficult fundamental stellar parameter to infer for isolated stars. While isochrone-based ages are in general imprecise for both main-sequence dwarfs and red giants, precise isochrone-based ages can be obtained for stars on the subgiant ...
David M. Nataf   +3 more
doaj   +1 more source

NanoMOF‐Based Multilevel Anti‐Counterfeiting by a Combination of Visible and Invisible Photoluminescence and Conductivity

open access: yesAdvanced Functional Materials, EarlyView.
This study presents novel anti‐counterfeiting tags with multilevel security features that utilize additional disguise features. They combine luminescent nanosized Ln‐MOFs with conductive polymers to multifunctional mixed‐matrix membranes and powder composites. The materials exhibit visible/NIR emission and matrix‐based conductivity even as black bodies.
Moritz Maxeiner   +9 more
wiley   +1 more source

Rising from the Ashes: A Metallicity-dependent Star Formation Gap Splits the Milky Way’s α Sequences

open access: yesThe Astrophysical Journal
The elemental abundance distribution of stars encodes the history of the gas-phase abundance in the Milky Way. Without a large, unbiased sample of highly precise stellar ages, the exact timing and nature of this history must be inferred from the ...
Angus Beane
doaj   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

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