Results 141 to 150 of about 13,860 (288)

Detection of the Actinide Th in an r-process-enhanced Star with Accretion Origin

The Astrophysical Journal
The thorium and six second-peak r -process element (56 ≤ Z ≤ 72) abundances are determined for the α -poor star LAMOST J1124+4535 based on a high-resolution spectrum obtained with the High Dispersion Spectrograph on the Subaru Telescope. The age of J1124+
Qianfan Xing, Gang Zhao, Wako Aoki, Haining Li, Jingkun Zhao, Tadafumi Matsuno, Takuma Suda   +6 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

A New Tidal Stream Discovered in Gaia DR3

The Astrophysical Journal
Thanks to the precise astrometric measurements of proper motions by the Gaia mission, a new tidal stellar stream has been discovered in the northern hemisphere. The distribution of star count shows that the stream is approximately 80° long and 1.°70 wide.
Hao Tian, Chao Liu, Changqing Luo, Xiang-Xiang Xue, Yujiao Yang   +4 more
doaj   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source

The Velocity Field of Our Milky Way Outer Stellar Halo Based on DESI DR2

The Astrophysical Journal
Using 64,000 halo K giants from the Dark Energy Spectroscopic Instrument second Data Release (DR2), we decompose the Milky Way (MW) stellar halo between 3 and 160 kpc into metal-rich (MR) and metal-poor (MP) components via a Gaussian mixture model.
Songting Li, Wenting Wang, Sergey E. Koposov, João A. S. Amarante, Alis J. Deason, Monica Valluri, Ting S. Li, Amanda Byström, Mika Lambert, Tian Qiu, Joan Najita, Gustavo E. Medina, Oleg Y. Gnedin, Leandro Beraldo e Silva, Richard A. N. Brooks, Raymond G. Carlberg, Namitha Kizhuprakkat, Jiaxin Han, Jessica Nicole Aguilar, Steven Ahlen, Davide Bianchi, David Brooks, Todd Claybaugh, Andrei Cuceu, Axel de la Macorra, Peter Doel, Andreu Font-Ribera, Jaime E. Forero-Romero, Simone Ferraro, Enrique Gaztañaga, Satya Gontcho A Gontcho, Gaston Gutierrez, Julien Guy, Klaus Honscheid, Dick Joyce, Anthony Kremin, Martin Landriau, Laurent Le Guillou, Aaron Meisner, Ramon Miquel, John Moustakas, Seshadri Nadathur, Will Percival, Francisco Prada, Ignasi Pérez-Ràfols, Graziano Rossi, Eusebio Sanchez, David Schlegel, Michael Schubnell, Ray Sharples, Joseph Harry Silber, David Sprayberry, Gregory Tarlé, Benjamin Alan Weaver, Rongpu Zhou, Hu Zou   +55 more
doaj   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Statistical Predictions of the Accreted Stellar Halos around Milky Way-Like Galaxies

The Open Journal of Astrophysics
In the $Λ$CDM paradigm, stellar halos form through the accretion and disruption of satellite galaxies. We introduce new semi-analytic modeling within the SatGen framework to track the ex-situ stellar components of Milky Way--like galaxies across large ...
J. Sebastian Monzon, Frank C. van den Bosch, Martin P. Rey   +2 more
doaj   +1 more source

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

StreamGen: Connecting Populations of Streams and Shells to Their Host Galaxies

The Astrophysical Journal
In this work, we study how the abundance and dynamics of populations of disrupting satellite galaxies change systematically as a function of host galaxy properties.
Adriana Dropulic, Nora Shipp, Stacy Kim, Zeineb Mezghanni, Lina Necib, Mariangela Lisanti   +5 more
doaj   +1 more source

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source