Anthelmintic Effect of Leucaena leucocephala Extract and Its Active Compound, Mimosine, on Vital Behavioral Activities in Caenorhabditis elegans [PDF]
Molecules, 2022 Helminth infections continue to be a neglected global threat in tropical regions, and there have been growing cases of anthelmintic resistance reported towards the existing anthelmintic drugs.
Amal Widaad +2 more
doaj +3 more sources
Comprehensive Network pharmacology and in vitro investigation of L-mimosine: unveiling multi-targeted therapeutic potential against breast cancer [PDF]
BMC Complementary Medicine and TherapiesBreast cancer remains the leading cause of mortality among women globally, primarily due to its heterogeneity and complex pathophysiology. Conventional treatments such as surgery, radiation therapy, and chemotherapy often face limitations, including ...
Jyoti Kumari Yadav +5 more
doaj +3 more sources
Investigating the role of mimosine-induced genotoxic stress through DNA repair profiling [PDF]
Molecular Therapy: Nucleic AcidsSmall molecules that induce DNA double-strand breaks (DSBs) are of significant interest for cancer therapy due to their ability to exploit repair vulnerabilities in tumor cells.
Sai Pallavi Pradeep +3 more
doaj +3 more sources
Natural Deep Eutectic Solvent based Ultrasound-assisted extraction: A green approach for extraction of sulfhydryl and mimosine from Leucaena leucocephala (Lam) de Wit seeds [PDF]
Heliyon, 2023 Leucaena leucocephala (Lam.) de Wit seeds, also known as river tamarind, contain sulfhydryl compounds that exhibit antioxidant effects. However, these seeds also possess a toxic effect from mimosine. In this study, the river tamarind seeds were extracted
Islamudin Ahmad +5 more
doaj +3 more sources
Rumen Synergistota: new insights into their role in mimosine and fluoroacetate toxicity of ruminant livestock [PDF]
Applied and Environmental MicrobiologyThis paper examines several rumen bacteria in the Synergistota phylum, specifically focusing on their potential to detoxify harmful compounds found in plants grazed by ruminants.
Christopher S. McSweeney +2 more
doaj +3 more sources
Insecticidal and Nematicidal Activities of Novel Mimosine Derivatives
Molecules, 2015 Mimosine, a non-protein amino acid, is found in several tropical and subtropical plants, which has high value for medicine and agricultural chemicals.
Jamnian Chompoo, Shinkichi Tawata
exaly +5 more sources
Transcriptional Analyses of Genes Related to Fodder Qualities in Giant Leucaena Under Different Stress Environments [PDF]
Frontiers in Plant Science, 2022 Leucaena leucocephala subsp. glabrata (giant leucaena) is a tree legume, whose foliage is used as a fodder for animals because of its high protein content. In spite of being a highly nutritious fodder, giant leucaena foliage has two undesirable secondary
Ahmed M. Bageel +2 more
doaj +2 more sources
Tropical Grasslands-Forrajes Tropicales, 2022 Giant leucaena produces high dry matter yields but the foliage contains mimosine, a non-protein amino acid that is toxic to animals, especially non-ruminants.
Michael D.H. Honda +3 more
doaj +2 more sources
In Vitro Antioxidant and Antimicrobial Potency of Mimosa pudica of Nepalese Terai Region: Insight into L-Mimosine as an Antibacterial Agent. [PDF]
Evid Based Complement Alternat Med, 2022 Aim The study aimed to evaluate the in vitro antioxidant and antimicrobial potency of Mimosa pudica found wildly in the Terai region of Nepal and assess its physicochemical properties, such as total phenolic content (TPC) and total flavonoid content (TFC)
Mandal AK +4 more
europepmc +2 more sources
Systemic Toxicity of L-Mimosine in Rabbits: A Non-Rodent Model for Safety Assessment. [PDF]
J Appl ToxicolL‐mimosine is a non‐protein amino acid primarily found in the Mimosoideae subfamily, with high concentrations in Leucaena leucocephala and Mimosa pudica.
Ferreira SM +6 more
europepmc +2 more sources