Mimosine Dipeptide Enantiomsers: Improved Inhibitors against Melanogenesis and Cyclooxygenase
Molecules, 2015 Melanogenesis plays an important role in the protection of skin against UV through production of melanin pigments, but abnormal accumulation of this pigment causes unaesthetic hyperpigmentation. Much effort is being made to develop effective depigmenting
Shinkichi Tawata
exaly +4 more sources
Insecticidal and Nematicidal Activities of Novel Mimosine Derivatives
Molecules, 2015 Mimosine, a non-protein amino acid, is found in several tropical and subtropical plants, which has high value for medicine and agricultural chemicals.
Shinkichi Tawata, Jamnian Chompoo
exaly +5 more sources
Investigating the role of mimosine-induced genotoxic stress through DNA repair profiling [PDF]
Molecular Therapy: Nucleic AcidsSmall molecules that induce DNA double-strand breaks (DSBs) are of significant interest for cancer therapy due to their ability to exploit repair vulnerabilities in tumor cells.
Sai Pallavi Pradeep +3 more
doaj +2 more sources
Transcriptional Analyses of Genes Related to Fodder Qualities in Giant Leucaena Under Different Stress Environments [PDF]
Frontiers in Plant Science, 2022 Leucaena leucocephala subsp. glabrata (giant leucaena) is a tree legume, whose foliage is used as a fodder for animals because of its high protein content. In spite of being a highly nutritious fodder, giant leucaena foliage has two undesirable secondary
Ahmed M. Bageel +2 more
doaj +2 more sources
Anthelmintic Effect of Leucaena leucocephala Extract and Its Active Compound, Mimosine, on Vital Behavioral Activities in Caenorhabditis elegans [PDF]
Molecules, 2022 Helminth infections continue to be a neglected global threat in tropical regions, and there have been growing cases of anthelmintic resistance reported towards the existing anthelmintic drugs.
Amal Widaad +2 more
doaj +2 more sources
Systemic Toxicity of L-Mimosine in Rabbits: A Non-Rodent Model for Safety Assessment. [PDF]
J Appl ToxicolABSTRACT L‐mimosine is a non‐protein amino acid primarily found in the Mimosoideae subfamily, with high concentrations in Leucaena leucocephala and Mimosa pudica. These plants are widely used in both human and animal nutrition, as well as in phytotherapeutic applications. While the toxic effects of L‐mimosine have been extensively studied in ruminants,
Ferreira SM +6 more
europepmc +2 more sources
Comprehensive Network pharmacology and in vitro investigation of L-mimosine: unveiling multi-targeted therapeutic potential against breast cancer [PDF]
BMC Complementary Medicine and TherapiesBreast cancer remains the leading cause of mortality among women globally, primarily due to its heterogeneity and complex pathophysiology. Conventional treatments such as surgery, radiation therapy, and chemotherapy often face limitations, including ...
Jyoti Kumari Yadav +5 more
doaj +2 more sources
Allelopathy and Allelochemicals of Leucaenaleucocephala as an Invasive Plant Species [PDF]
Plants, 2022 Leucaena leucocephala (Lam.) de Wit is native to southern Mexico and Central America and is now naturalized in more than 130 countries. The spread of L. leucocephala is probably due to its multipurpose use such as fodder, timber, paper pulp, shade trees,
Hisashi Kato-Noguchi, Denny Kurniadie
doaj +2 more sources
Natural Deep Eutectic Solvent based Ultrasound-assisted extraction: A green approach for extraction of sulfhydryl and mimosine from Leucaena leucocephala (Lam) de Wit seeds [PDF]
Heliyon, 2023 Leucaena leucocephala (Lam.) de Wit seeds, also known as river tamarind, contain sulfhydryl compounds that exhibit antioxidant effects. However, these seeds also possess a toxic effect from mimosine. In this study, the river tamarind seeds were extracted
Islamudin Ahmad +5 more
doaj +2 more sources
A new spin on chemotaxonomy: Using non-proteogenic amino acids as a test case. [PDF]
Appl Plant SciAbstract Premise Specialized metabolites serve various roles for plants and humans. Unlike core metabolites, specialized metabolites are restricted to certain plant lineages; thus, in addition to their ecological functions, specialized metabolites can serve as diagnostic markers of plant lineages.
Gibson M +4 more
europepmc +2 more sources