Results 11 to 20 of about 2,207 (198)

Rumen Synergistota: new insights into their role in mimosine and fluoroacetate toxicity of ruminant livestock [PDF]

open access: yesApplied and Environmental Microbiology
This paper examines several rumen bacteria in the Synergistota phylum, specifically focusing on their potential to detoxify harmful compounds found in plants grazed by ruminants.
Christopher S. McSweeney   +2 more
doaj   +2 more sources

Evolution of the Defense Compounds Against Biotic Stressors in the Invasive Plant Species Leucaena leucocephala [PDF]

open access: yesMolecules
Leucaena leucocephala (Lam.) de Wit is listed in the world’s 100 worst alien invasive species because of the risks it poses to native plant communities.
Hisashi Kato-Noguchi, Midori Kato
doaj   +2 more sources

Nuclear Import Defects Drive Cell Cycle Dysregulation in Neurodegeneration. [PDF]

open access: yesAging Cell
Overview of Dysregulated Cell Cycle Mechanisms in Neuronal Cells. A nuclear import block drives cell cycle re‐entry from G0, culminating in cell cycle arrest at G1/S. This cell cycle arrest is associated with activation of CKIs from the INK locus (p15, p16, p18, p19) and Cip/Kip (p21, p27) which act on specific CDK/Cyclin complexes.
Plessis-Belair J   +3 more
europepmc   +2 more sources

Mimosine

open access: yes, 2023
Mimosine parameters for Amber ff99sb and 03 force fields in Gromacs ...
David De Sancho
core   +8 more sources

EVALUATION OF MIMOSINE TOXICITY IN GOAT AND BUFFALO ERYTHROCYTE SYSTEM IN VITRO [PDF]

open access: yesExploratory Animal and Medical Research, 2012
Dose and time dependent effect of mimosine in goat and buffalo erythrocyte system in vitro have been evaluated in the present study. The results obtained exhibit that mimosine induces hemolysis in both mode of studies with concomitant increase in ...
Arun Kumar Brahmachari
doaj   +2 more sources

A maceration treatment of leucaena foliage improves its nutritional value by reducing mimosine concentration

open access: yesTropical Grasslands-Forrajes Tropicales, 2022
Giant leucaena produces high dry matter yields but the foliage contains mimosine, a non-protein amino acid that is toxic to animals, especially non-ruminants.
Michael D.H. Honda   +3 more
doaj   +1 more source

Influence of non-protein amino-acid mimosine in peptide conformational propensities from novel Amber force field parameters [PDF]

open access: yes, 2021
Mimosine is a non-protein amino acid derived from plants known for its ability to bind to divalent or trivalent metal cations such as Zn$^{2+}$, Ni$^{2+}$, Fe$^{2+}$ or Al$^{3+}$.
David, De Sancho   +2 more
core   +2 more sources

Removal of Mimosine from Leucaena leucocephala (Lam.) de Wit Seeds to Increase Their Benefits as Nutraceuticals

open access: yesPharmaceutical Sciences and Research, 2020
The Leucaena leucocephala (Lam.) de Wit tree contains pharmacologically active compounds and can easily be found in abundant quantities. The utilization of this tree as a source of nutraceuticals would increase its value.
Sri Wardatun   +4 more
doaj   +1 more source

Mimosine Targets Serine Hydroxymethyltransferase [PDF]

open access: yesJournal of Biological Chemistry, 1996
The plant amino acid, mimosine, is an extremely effective inhibitor of DNA replication in mammalian cells (Mosca, P. J., Dijkwel, P. A., and Hamlin, J. L. (1992) Mol. Cell. Biol. 12, 4375-4383). Mimosine appears to prevent the formation of replication forks at early-firing origins when delivered to mammalian cells approaching the G1/S boundary, and ...
H B, Lin   +5 more
openaire   +2 more sources

Mimosine concentration in Leucaena leucocephala under various environmental conditions

open access: yesTropical Grasslands-Forrajes Tropicales, 2019
Keynote paper presented at the International Leucaena Conference, 1‒3 November 2018, Brisbane, Queensland, Australia. Leucaena leucocephala (leucaena) is a multipurpose tropical tree-legume that is highly resistant to many biotic and abiotic stresses ...
Michael D.H. Honda, Dulal Borthakur
doaj   +1 more source

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