Results 21 to 30 of about 169 (131)

Gut microbiology – broad genetic diversity, yet specific metabolic niches

Animal, 2008
Analysis of 16S ribosomal RNA (rRNA)-encoding gene sequences from gut microbial ecosystems reveals bewildering genetic diversity. Some metabolic functions, such as glucose utilisation, are fairly widespread throughout the genetic spectrum.
R. John Wallace
doaj   +1 more source

Wound healing improvement with PHD-2 silenced fibroblasts in diabetic mice. [PDF]

PLoS ONE, 2013
BACKGROUND: Hypoxia-inducible factor 1α is the central regulator of the hypoxia-induced response which results in the up-regulation of angiogenic factors. Its activity is under precise regulation of prolyl-hydroxylase domain 2.
Xiongliang Zhang, Xiaoyu Yan, Liang Cheng, Jiezhi Dai, Chunyang Wang, Pei Han, Yimin Chai   +6 more
doaj   +1 more source

Tolerance and Excretion of Mimosine in the Fowl [PDF]

Nature, 1965
Hegarty, Schinckel and Court1 have reported the use of isolated mimosine (β-[N-(3-hydroxypyridone-4)]-α-aminopropionic acid) in metabolism investigations with sheep. They reported that the major metabolite 3,4-di-hydroxypyridine (DHP) was present in the urine, and that degradation of mimosine to DHP occurred in the rumen, the animal being unable to ...
openaire   +2 more sources

Physical Dependence and Inhalation Toxicity in Rats Exposed to Smoke of Mimosa pudica L. [PDF]

Research Journal of Pharmacognosy
Background and Objectives: Mimosa pudica L., belonging to the Fabaceae family, has been used in the Cuban traditional culture by exposure to smoke of aerial parts combustion and in the smokable form of cigarettes, for recreational or leisure purposes and
Onel Fong Lores, Clara Azalea Berenguer Rivas, Jorge Eduardo de la Vega Acosta, Juan Esmérido Betancourt Hernández, Frankoe Alvarez Limonta, Yoandra Mora Tassé, Miriam Magale Santiago Ortiz, Humberto Joaquín Morris Quevedo, Marcos Meneses Mayo*   +8 more
doaj   +1 more source

Directed Evolution Improves the Catalytic Efficiency of APEX2‐Mediated Proximity‐Dependent RNA Labeling

Advanced Science, Volume 13, Issue 32, 9 June 2026.
ABSTRACT Engineered ascorbate peroxidase APEX2 has been widely used for spatially restricted profiling of subcellular biomolecules, but its catalytic efficiency toward newly developed probes such as biotin‐aniline (Btn‐An) remains suboptimal. To overcome this limitation, we performed yeast surface display‐based directed evolution to enhance APEX2 ...
Gang Wang, Yi Li, Peiyuan Meng, Peng Zou
wiley   +1 more source

THE HEPATOTOXICITY OF MIMOSINE IN PRECISION CUT GOAT LIVER SLICE SYSTEM [PDF]

Exploratory Animal and Medical Research, 2011
Mimosine, a non protein toxic amino acid, induced toxicity in precision cut goat liver slice system had been studied in term of its effect on certain enzymatic and metabolic parameters in vitro.
Arun Kumar Brahmachari
doaj  

Khám phá các phân tử thuốc từ cơ sở dữ liệu Drugbank như là hợp chất ức chế Kinesin Eg5 ở người bằng docking phân tử

Tạp chí Khoa học Đại học Cần Thơ, 2022
Kinesin Eg5 đóng một vai trò quan trọng trong giai đoạn đầu của quá trình nguyên phân và là một mục tiêu thú vị để thiết kế các loại chất ức chế. Trong nghiên cứu này, sự kết hợp giữa mô hình nghiên cứu 2D-QSAR và docking  phân tử đã được thực hiện trên
Nguyễn Ngọc Lê, Nguyễn Cường Quốc, Trần Quang Đệ   +2 more
doaj   +1 more source

Evaluation of Liver Damage and Herbal Detoxification of Coral Reef Fish Caused by Ammonia Stress

Aquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.
Slybum marianum can reduce ammonia stress and enhance liver protection in marine fish. ABSTRACT Ammonia nitrogen can cause serious toxicological damage to fish and cause fish death. This study focused on liver damage caused by ammonia nitrogen stress in coral reef fish and used herbal extracts to improve ammonia poisoning and prevent liver tissue ...
Wei‐Ting Sun, You‐Ren Lai, De‐Sing Ding, Chih‐Hung Pan   +3 more
wiley   +1 more source

Do Uncommon Plant Phenolic Compounds Have Uncommon Properties? A Mini Review on Novel Flavonoids

Journal of Bioresources and Bioproducts, 2021
Unique plants and their properties, once considered synonymous to medicine, remain a potent source for new compounds in modern science. Plant polyphenols and natural products continue to be investigated for effective treatments for the most persistent of
James T. Carrillo, Dulal Borthakur
doaj   +1 more source

Distinct Defence Mechanisms of Allelopathic Rice Against Quinclorac‐Susceptible and ‐Resistant Barnyardgrass: Involvement of Specific Metabolites and Rhizosheath Microbiota

Plant Biotechnology Journal, Volume 24, Issue 6, Page 3876-3896, June 2026.
ABSTRACT Allelopathic rice is increasingly recognised as a promising strategy for sustainable weed management. Resistance to the herbicide quinclorac is widespread in barnyardgrass, but it remains unclear whether allelopathic rice exerts the same defence against herbicide‐susceptible and ‐resistant barnyardgrass. We conducted integrated transcriptomic,
Shuyan Li, Qiling Yan, Jianhua Tong, Yongfeng Li, Lianyang Bai, Qiong Peng   +5 more
wiley   +1 more source