Results 21 to 30 of about 2,207 (198)

Generation of reactive oxygen species by hydroxypyridone compound/iron complexes

Redox Report, 2020
Objectives: Prooxidant properties of iron-binding hydroxypyridone compounds including deferiprone and mimosine were analyzed. Methods: Hydroxypyridone/iron-dependent production of reactive oxygen species was evidenced by the inactivation of aconitase ...
Keiko Murakami, Masataka Yoshino
doaj   +1 more source

The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model

eLife, 2020
Dose-limiting toxicities for cisplatin administration, including ototoxicity and nephrotoxicity, impact the clinical utility of this effective chemotherapy agent and lead to lifelong complications, particularly in pediatric cancer survivors.
Jaime N Wertman, Nicole Melong, Matthew R Stoyek, Olivia Piccolo, Stewart Langley, Benno Orr, Shelby L Steele, Babak Razaghi, Jason N Berman   +8 more
doaj   +1 more source

Mimosine functionalized gold nanoparticles (Mimo-AuNPs) suppress β-amyloid aggregation and neuronal toxicity

Bioactive Materials, 2021
Evidence suggests that increased level/aggregation of beta-amyloid (Aβ) peptides initiate neurodegeneration and subsequent development of Alzheimer's disease (AD). At present, there is no effective treatment for AD. In this study, we reported the effects
Bibin G. Anand, Qi Wu, Govindarajan Karthivashan, Kiran P. Shejale, Sara Amidian, Holger Wille, Satyabrata Kar   +6 more
doaj   +1 more source

L-mimosine increases the production of vascular endothelial growth factor in human tooth slice organ culture model. [PDF]

, 2015
AIM To assess the pro-angiogenic and pro-inflammatory capacity of the dentine-pulp complex in response to the prolyl hydroxylase inhibitor L-mimosine in a tooth slice organ culture model.
Gruber, Reinhard, Agis, H, Trimmel, K, Müller, H-D, Nürnberger, S, Cvikl, Barbara, Moritz, A   +6 more
core   +1 more source

Effect of Feeding Different Cultivars of Leucaena leucocephala on Rumen-Based in vitro Anaerobic Fermentations

Proceedings, 2020
The leguminous forage shrub, Leucaena leucocephala, is one of the few nutritional options available to significantly improve beef productivity in Northern Australia.
Diane Ouwerkerk, Anita Maguire, Jenny Gravel, Cathy Minchin, Michael Gravel, Athol Klieve, Ros Gilbert   +6 more
doaj   +1 more source

Does the size of larval groups influence the effect of metabolic inhibitors on the development of Phormia regina (Diptera: Calliphoridae) larvae?

European Journal of Entomology, 2002
A series of experiments were conducted to compare the susceptibility of P. regina larvae reared in isolation or in groups to the effects of diet-borne metabolic inhibitors: chlorogenic acid (CGA) and mimosine.
Paul W.C. GREEN, Monique S.J. SIMMONDS, Wally M. BLANEY   +2 more
doaj   +1 more source

DNA Breaks Induction by Mimosine

Zeitschrift für Naturforschung C, 2003
Abstract Mouse erythroleukemic F4 N cells were treated with mimosine, etoposide, Fe(II)-EDTA, and Cu(II) in the presence of ascorbate. DNA was isolated and subjected to agarose gel electrophoresis and the size and distribution of the DNA fragments produced by the agents were compared.
Emil, Mladenov, Boyka, Anachkova
openaire   +2 more sources

Inhibition of activity of collagen degradation in cartilage of patients with osteoarthrosis byactivation of glycolysis

Остеопороз и остеопатии, 2011
Aim. To study the effect of glycolysis activators deferrioxamine (DFO), CoCl2, V(SO4)2 and mimosine on collagen cleavage activity by collagenase in osteoarthritic (OA) articular cartilage explants. Materials and methods.
E. V. Chetina, E. V. Chetina
doaj   +1 more source

Mimosine concentration in giant leucaena (Leucaena leucocephala subsp. glabrata) fluctuates with age and plant part

Tropical Grasslands-Forrajes Tropicales
Giant leucaena is a multipurpose tree-legume found throughout the tropics and sub-tropics. Its foliage is used as animal fodder due to high protein and fiber.
Michael Honda, Dulal Borthakur
doaj   +1 more source

Tolerance and Excretion of Mimosine in the Fowl [PDF]

Nature, 1965
Hegarty, Schinckel and Court1 have reported the use of isolated mimosine (β-[N-(3-hydroxypyridone-4)]-α-aminopropionic acid) in metabolism investigations with sheep. They reported that the major metabolite 3,4-di-hydroxypyridine (DHP) was present in the urine, and that degradation of mimosine to DHP occurred in the rumen, the animal being unable to ...
openaire   +2 more sources