Results 101 to 110 of about 93,504 (350)

Mineralocorticoid receptor overactivation-induced remodeling of obese adipose tissue [PDF]

Xin yixue
Obesity is a chronic disease caused by the long-term interaction of multiple environmental factors on a specific genetic background. Among these factors， the overactivation of mineralocorticoid receptors （MR） plays a significant role in adipose tissue ...
WEN Runzhi, WANG Li, ZHAO Naiqian
doaj   +1 more source

Mineralocorticoid receptor blockade during a rat's first violent encounter inhibits its subsequent propensity for violence. [PDF]

, 2013
In individuals naive to serious conflict in an unfamiliar environment, violence has long-lasting effects on subsequent aggressive behavior. This effect of the stressful experience of a first violent conflict occurs in victims as well as offenders.
Haller, József, Kloet, E. R., Kruk, M. R., Meelis, W.   +3 more
core   +1 more source

Plasma renin measurements are unrelated to mineralocorticoid replacement dose in patients with primary adrenal insufficiency.

Journal of Clinical Endocrinology and Metabolism, 2019
CONTEXT No consensus exists for optimization of mineralocorticoid therapy in patients with primary adrenal insufficiency. OBJECTIVE To explore the relationship between mineralocorticoid replacement dose, plasma renin concentration (PRC) and clinically ...
R. Pofi, R. Pofi, A. Prete, V. Thornton-Jones, J. Bryce, S. Ali, S. F. Ahmed, A. Balsamo, F. Baronio, Amalia Cannuccia, Ayla Güven, T. Guran, F. Darendeliler, C. Higham, W. Bonfig, L. D. Vries, L. D. Vries, Tania A. S. S. Bachega, Mirela C Miranda, B. Mendonca, V. Iotova, M. Korbonits, N. Krone, R. Krone, A. Lenzi, Wiebke Arlt, Wiebke Arlt, R. Ross, A. Isidori, J. Tomlinson   +29 more
semanticscholar   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

The effect of cumulative stress exposure on depressive symptoms is modified by a mineralocorticoid receptor haplotype

European Journal of Psychotraumatology, 2012
Rationale/statement of the problem : Stress exposure increases the risk for the development of depression. The leading hypothesis is that stress exposure only increases the risk in individuals combining a vulnerable genetic background with (repeated ...
Christian H. Vinkers, Willemijn van Gastel, Jurjen J. Luykx, Chris Schubart, Marian Joëls, René S. Kahn, Marco P.M. Boks   +6 more
doaj   +1 more source

PATIENT WITH CHRONIC HEART FAILURE. RATIONAL CHOICE OF THERAPY

Рациональная фармакотерапия в кардиологии, 2017
The theory of chronic hyperactivation of neurohormonal systems, in particular, sympathoadrenal and renin-angiotensin-aldosterone, is the basis of modern concepts of the pathogenesis of heart failure. The medicinal blocking of these two systems has proved
O. M. Drapkina, D. U. Akasheva
doaj   +1 more source

Genetic Insights and Lifelong Management of Aldosterone Synthase Deficiency: A Case of Hyperreninemic Hypoaldosteronism. [PDF]

Clin Case Rep
ABSTRACT Aldosterone synthase deficiency is a rare cause of neonatal salt‐wasting and failure to thrive. Routine newborn electrolyte screening after 5 days of life is vital for early detection and prevention of life‐threatening crises. Genetic confirmation enables targeted fludrocortisone therapy, ensuring favorable growth and developmental outcomes.
Ahmed MMH, Waris R, Batool S, Omarzai RG, Rehman A.   +4 more
europepmc   +2 more sources

Safety and efficacy of fluticasone propionate in the topical treatment of skin diseases [PDF]

, 2004
Fluticasone propionate - the first carbothioate corticosteroid - has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance treatment of ...
Atsuta J, Boner AL, Bridgman A, Callen J, Delescluse J, Dooms-Goossens AE, Dykes PJ, Falcoz C, Fisher DA, Goossens A, Harding SM, Hogger P, James M, Johnson M, Johnson M, Juhlin L, Katz HI, Korting HC, Lebwohl M, Li JT, Liu XQ, Llewellyn-Jones CG, Lucky AW, McKenzie AW, McLean HM, Nurnberger FG, Phillipps GH, Roberts DT, Spencer CM, Tharp MD, Venning VA, Wilkinson SM, Wolkerstorfer A, Young MMR   +33 more
core   +1 more source

Implementation of guideline‐recommended medical therapy for patients with heart failure in Europe

ESC Heart Failure, Volume 12, Issue 2, Page 790-798, April 2025.
Abstract Physicians' adherence to guideline‐recommended heart failure (HF) treatment remains suboptimal, especially regarding the target doses. In particular, there is evidence that non‐cardiologists are less compliant with HF guideline recommendations. This is likely to have a detrimental impact on patients' survival, readmissions and quality of life.
Maurizio Volterrani, Petar Seferovic, Gianluigi Savarese, Ilaria Spoletini, Egidio Imbalzano, Antoni Bayes‐Genis, Ewa Jankowska, Michele Senni, Marco Metra, Ovidiu Chioncel, Andrew J. S. Coats, Giuseppe M. C. Rosano   +11 more
wiley   +1 more source

Analysis of the usefulness and benefits of ultrafiltration in cardiorenal syndrome: A systematic review

ESC Heart Failure, Volume 12, Issue 2, Page 1194-1202, April 2025.
Abstract Aims Cardiac decompensation in cardiorenal syndrome (CRS) results in systemic congestion usually treated with diuretics. When despite high doses of diuretics, response is poor, ultrafiltration (UF) appears to be a useful and safe technique.
Borja Guerrero Cervera, Raquel López‐Vilella, Víctor Donoso Trenado, María Peris‐Fernández, Paula Carmona, Amparo Soldevila, Sergi Tormo, Ramón Devesa, María Jesús Montero Hernández, Luis Martínez Dolz, Julio Hernández Jaras, Pilar Sánchez‐Pérez, Luis Almenar‐Bonet   +12 more
wiley   +1 more source