Results 131 to 140 of about 59,126 (309)
ESC Heart Failure, EarlyView.Impact of empagliflozin in patients with and without T2D or CKD in the EMPACT‐MI trial. Baseline characteristics, HF outcomes and subgroup analysis of efficacy endpoints are shown. # Hazard ratios estimated via Cox proportional hazard model (unless indicated otherwise). ^ Rate ratios via negative binomial regression.
Francesco Fioretti +23 more
wiley +1 more source
Predicting acute decompensated heart failure using circadian markers from heart rate time series
ESC Heart Failure, EarlyView.Circadian metrics—amplitude, mesor, and acrophase—derived from a wrist‐worn heart rate monitor can predict acute decompensated heart failure (ADHF) up to 21 days before onset. In 65 post‐ADHF patients, an LSTM model achieved 74% sensitivity, and 73% specificity trained on 21‐day sequences. These findings support circadian rhythm analysis as a promising
Valerie A. A. van Es +9 more
wiley +1 more source
Eplerenone reduces lymphangiogenesis in the contralateral kidneys of UUO rats
Scientific ReportsInflammation and fibrosis often occur in the kidney after acute injury, resulting in chronic kidney disease and consequent renal failure. Recent studies have indicated that lymphangiogenesis can drive renal inflammation and fibrosis in injured kidneys ...
Juan Hao +9 more
doaj +1 more source
Treatment of Hypertension in a Child With 11Beta-Hydroxylase Deficiency: A Case Report
Journal of Pediatrics Review, 2022 Background: 11beta-hydroxylase deficiency (11βOHD) is clinically presented with external genitalia virilization in girls and precocious puberty in boys. Low renin hypertension occurs in both sexes.
Fatemeh Saffari, Banafsheh Arad
doaj
High aldosterone-to-renin variants of CYP11B2 and pregnancy outcome [PDF]
, 2017 Background. Increased aldosterone concentrations and volume expansion of normal pregnancies are hallmarks of normal pregnancies and blunted in pre-eclampsia.
Baumann, Marc +6 more
core
ESC Heart Failure, EarlyView.Abstract Aims The EMAIL‐HF trial aims to evaluate whether a digital guideline implementation strategy can increase and accelerate initiation of sodium‐glucose co‐transporter 2 (SGLT2) inhibitors in patients with heart failure (HF). Methods and results EMAIL‐HF is a pragmatic, registry‐based, randomized controlled trial including patients with a ...
Mariam Elmegaard +21 more
wiley +1 more source
492 STEROID SPECIFICITY OF RAT RENAL MINERALOCORTICOID RECEPTORS AFTER IN SITU PERFUSION [PDF]
, 1985 Hironobu Sasano +2 more
openalex +1 more source
ESC Heart Failure, EarlyView.Abstract Aims There is growing recognition of the burden and prognostic significance of WHF treated in the outpatient setting. However, there is currently a lack of prospective real‐world data in this area of HF care. This study aims to analyse the natural history of outpatient WHF.
Joseph McCambridge +6 more
wiley +1 more source
FIDELIO study: significance and place of finerenone as nonsteroidal mineralocorticoid receptor antagonist in therapy of patients with chronic kidney disease in type 2 diabetes [PDF]
, 2023 Минара Шамхаловна Шамхалова +2 more
openalex +1 more source