Results 131 to 140 of about 35,682 (244)

Effects of age, sex, and renal function on bowel movement‐improving effects of Bifidobacterium bifidum G9‐1 on constipation in patients with type 2 diabetes mellitus and chronic kidney disease: A prespecified subgroup analysis of the BIRDIE study

Journal of Diabetes Investigation, EarlyView.
This prespecified subgroup analysis of the BIRDIE study demonstrated that Bifidobacterium bifidum G9‐1 improved stool consistency, bowel movement, and quality of life in patients with type 2 diabetes mellitus, chronic kidney disease, and specifically in age ≥ 65 years, male, and those with eGFR ≥60 mL/min/1.73 m2.
Fuki Ikeda, Junko Sato, Hidenori Yoshii, Hiroaki Satoh, Hirotsugu Uzawa, Daisuke Sugimoto, Reina Muto, Yuya Nishida, Hirotaka Watada   +8 more
wiley   +1 more source

The non-steroidal mineralocorticoid receptor blocker esaxerenone reduces glomerular hyperfiltration and albuminuria. [PDF]

Nephrol Dial Transplant
Tatsugawa R, Kidokoro K, Iwakura T, Hirano A, Kajimoto E, Takasu M, Wada M, Kitao H, Wada Y, Gyarmati G, Kishi S, Nagasu H, Cherney DZI, Peti-Peterdi J, Sasaki T, Kashihara N.   +15 more
europepmc   +1 more source

Expression of corticoid‐regulatory genes in the gills of Atlantic salmon (Salmo salar) parr and smolt and during salinity acclimation

Journal of Fish Biology, EarlyView.
Abstract In teleost fishes, cortisol is the major corticoid and has both glucocorticoid and mineralocorticoid actions. However, how fish tissues discriminate between these distinct corticosteroid actions is unclear. In mammals, the major factors responsible for intracellular corticosteroid regulation are glucocorticoid receptors (grs) and the ...
Makoto Kusakabe, Takashi Yada, Graham Young, Amy M. Regish, Stephen D. McCormick   +4 more
wiley   +1 more source

Take my breath away: Defining the oxygen saturation threshold for fish cortisol stress response

Journal of Fish Biology, EarlyView.
Abstract Human activities are affecting the number, size and severity of hypoxic zones in aquatic ecosystems. As oxygen is one of the most important abiotic factors affecting fish biology, exposure to low levels of dissolved oxygen may lead to a reduction in fitness.
Sébastien Alfonso, Benjamin Geffroy, Pierluigi Carbonara, Lola Toomey, Eduardo Bessa   +4 more
wiley   +1 more source

Mineralocorticoid Receptor Antagonists in Chronic Kidney Disease: Clinical Evidence, Pharmacology, and Drug-Drug Interactions for Personalized Management of Hyperkalemia. [PDF]

Int J Mol Sci
Hirai T, Katayama K.
europepmc   +1 more source

Left Ventricular wall Thickness and Decrement Evoked Potentials in Ablation of Ischemic Ventricular Tachycardia

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Introduction Preprocedural imaging can improve the success rate of ventricular tachycardia (VT) ablation. Left ventricular wall thickness (LVWT) measured by cardiac computed tomography (CT) can be used to identify infarct regions. We sought to determine whether an association exists between left ventricular wall thickness (LVWT) as obtained ...
Alwin B. P. Noordman, Ahmed S. Yassin, Michiel Rienstra, Alexander H. Maass, Yuri Blaauw   +4 more
wiley   +1 more source

Mineralocorticoid receptor antagonists in heart failure with sustained monomorphic ventricular tachycardia: comparative analysis of spironolactone versus eplerenone. [PDF]

Open Heart
Szakál I, Komlósi F, Tóth P, Arnóth B, Bohus G, Vámosi P, Szegedi N, Salló Z, Osztheimer I, Perge P, Orbán G, Kardos A, Merkely B, Gellér L, Nagy KV.   +14 more
europepmc   +1 more source

Inpatient Cardiac Resynchronization Therapy During Heart Failure Hospitalization: A Distinct High‐Risk Phenotype

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background The role of cardiac resynchronization therapy (CRT) during hospitalization for heart failure (HFH) is uncertain, because hospitalized patients were routinely excluded from landmark CRT trials. Despite this, CRT implantation during HFH is common.
Oliver Rees, James Dargan, Jemima Weir, Robin Ray, Giuseppe Rosano, Fadi Johura   +5 more
wiley   +1 more source

Comparative Effects of Mineralocorticoid Receptor Antagonism on Organ Dysfunction in COVID-19-Associated ARDS. [PDF]

Biomedicines
Dumanlı GY, Dilken O, Demirkıran O, Dikmen Y, Uzun H, Tabak O.   +5 more
europepmc   +1 more source

Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski, Phetcharawan Lye, Enrrico Bloise, Stephen G. Matthews   +3 more
wiley   +1 more source