Results 201 to 210 of about 26,548 (293)

Comparison of SGLT2 Inhibitors for New‐Onset Proteinuria Risk in Patients With Type 2 Diabetes and Preserved Kidney Function

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4314-4325, May 2026.
ABSTRACT Aims To compare the effects of individual SGLT2 inhibitors on preventing new‐onset proteinuria in patients with type 2 diabetes and preserved kidney function. Materials and Methods A target trial emulation was performed using commercially available databases, including health checkups and claims data, between April 1, 2014 and March 31, 2023 ...
Hiroki Nobayashi, Michihiro Satoh, Takuo Hirose, Shingo Nakayama, Yutaro Iwabe, Hideaki Hashimoto, Takahisa Murakami, Kouji Okada, Takefumi Mori, Hirohito Metoki   +9 more
wiley   +1 more source

Mineralocorticoid Receptor Antagonist Use Among Patients With Chronic Kidney Disease Who Transitioned to Dialysis. [PDF]

Kidney Med
Tong EM, Zhou H, Pak K, Huang CW, Broder BI, Sim JJ.   +5 more
europepmc   +1 more source

Benefits of the Non-Steroidal Mineralocorticoid Receptor Antagonist Finerenone in Metabolic Syndrome-Related Heart Failure with Preserved Ejection Fraction. [PDF]

Int J Mol Sci, 2023
Lima-Posada I, Stephan Y, Soulié M, Palacios-Ramirez R, Bonnard B, Nicol L, Kolkhof P, Jaisser F, Mulder P.   +8 more
europepmc   +1 more source

Cardio‐Kidney‐Metabolic Therapy Use Among Adults With Type 1 Diabetes and Chronic Kidney Disease

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4344-4351, May 2026.
ABSTRACT Aims Kidney and cardiovascular diseases are highly prevalent among patients with Type 1 diabetes. To date, no randomised clinical trial has reported on the impact of novel cardio‐kidney‐metabolic (CKM) therapies (GLP‐1RA and SGLT2i) on kidney function in this population.
M. Luiza Caramori, Enrico Repetto, Christopher Perkins, Ambarish Pandey, Peter Rossing   +4 more
wiley   +1 more source

Finerenone: a breakthrough mineralocorticoid receptor antagonist for heart failure, diabetes and chronic kidney disease. [PDF]

Egypt Heart J
Pradhan A, Tripathi UC.
europepmc   +1 more source

Finerenone, a Non-Steroidal Mineralocorticoid Receptor Antagonist, Reduces Vascular Injury and Increases Regulatory T-Cells: Studies in Rodents with Diabetic and Neovascular Retinopathy. [PDF]

Int J Mol Sci, 2023
Jerome JR, Deliyanti D, Suphapimol V, Kolkhof P, Wilkinson-Berka JL.   +4 more
europepmc   +1 more source

Brain Proteomic Responses to Glucocorticoids and Their Relationship With Transcriptome: A Systematic Meta‐Analysis

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
An overlap between proteomic and transcriptomic findings in experiments testing brain responses to glucocorticoids. A shows that 455 proteins responsive to glucocorticoids were not confirmed at the transcriptomic level while 4 proteins were matched with significant differences in mRNA in all 8 datasets derived from transcriptomic experiments.
Grzegorz R. Juszczak
wiley   +1 more source

Effects of Semaglutide With or Without Concomitant Mineralocorticoid Receptor Antagonist Use in Participants With Type 2 Diabetes and Chronic Kidney Disease: A FLOW Trial Prespecified Secondary Analysis. [PDF]

Diabetes Care
Rossing P, Bakris G, Perkovic V, Pratley R, Tuttle KR, Mahaffey KW, Idorn T, Belmar N, Bosch-Traberg H, Rasmussen S, Busch RS, Schmieder RE, Gillard P, Mann JFE, FLOW Investigator Group .   +14 more
europepmc   +1 more source

Modifying chronic kidney disease progression with the mineralocorticoid receptor antagonist finerenone in patients with type 2 diabetes. [PDF]

Diabetes Obes Metab, 2022
DeFronzo RA, Bakris GL.
europepmc   +1 more source

Distinct Effects of Maternal Stress and Exercise on Offspring Metabolic Health

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Maternal exercise improves glucose tolerance in adult male offspring, but this benefit is blunted by maternal stress. Exercise increases offspring corticosterone levels independent of stress, whereas maternal stress upregulates glucocorticoid and mineralocorticoid receptor expression in brown adipose tissue, which is prevented by maternal exercise ...
Felix T. Yang, Joao V. Esteves, Lisa A. Baer, Kelsey M. Pinckard, Branden G. Verosky, Olivia A. Togliatti, Caden Burkhart, Sara A. Alzuhaili, Nickolai P. Seculov, Tamar L. Gur, Kristin I. Stanford   +10 more
wiley   +1 more source