Results 61 to 70 of about 201,814 (275)
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
The minimal work cost of information processing [PDF]
AbstractIrreversible information processing cannot be carried out without some inevitable thermodynamical work cost. This fundamental restriction, known as Landauer’s principle, is increasingly relevant today, as the energy dissipation of computing devices impedes the development of their performance.
Philippe Faist +3 more
openaire +5 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
With rising levels of obesity and associated non-communicable diseases in Africa, there is an increasing concern with regards to ultra-processed foods.
Hannah Ameye, Katrin Glatzel
doaj +1 more source
"Null" (unverarbeitete) bis minimal verarbeitete Lebensmittel erfreuen sich zunehmender Beliebtheit, da die Verbraucher immer mehr Wert auf die Herkunft unverarbeiteter und minimal verarbeiteter Lebensmittel legen. Minimale Verarbeitungstechniken haben sich als äußerst wirksam erwiesen, um die Haltbarkeit zu verlängern und die Produktqualität und ...
Nedić Tiban, Nela +2 more
openaire +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Fresh vegetables are highly recommended in any diet, virtually without quantitative restriction. The consumption of minimally processed vegetables has increased in recent years, among others due to their convenience and health benefits.
A. Kukułowicz
doaj +1 more source
Laryngoscopic Image Stitching for View Enhancement and Documentation - First Experiences [PDF]
One known problem within laryngoscopy is the spatially limited view onto the hypopharynx and the larynx through the endoscope. To examine the complete larynx and hypopharynx, the laryngoscope can be rotated about its main axis, and hence the physician ...
Bergen, Tobias +5 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source

