Results 51 to 60 of about 1,401,422 (284)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Intra-arterial adenoviral mediated tumor transfection in a novel model of cancer gene therapy

Molecular Cancer, 2006
Background The aim of the present study was to develop and characterize a novel in vivo cancer gene therapy model in which intra-arterial adenoviral gene delivery can be characterized.
Siemionow Maria, DiCorleto Paul E, Porvasnik Stacy L, Cabrera Gustavo, Goldman Corey K   +4 more
doaj   +1 more source

Switching Tube-Based MPC: Characterization of Minimum Dwell-Time for Feasible and Robustly Stable Switching [PDF]

IEEE Transactions on Automatic Control, 2019
We study the problem of characterizing mode dependent dwell-times that guarantee safe and stable operation of disturbed switching linear systems in an MPC framework. We assume the switching instances are not known a-priori, but instantly at the moment of switching.
Bernardo A. Hernandez Vicente, Paul A. Trodden   +1 more
openaire   +3 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A dwelling place in bits

, 2006
This paper considers computed means for constructing and interrogating prehistoric architectures. We ask where the ‘landscapes’ created through points and arcs divide us from the prehistory we seek and whether in fact these virtual landscapes offer new ...
Cripps, Paul, Earl, Graeme, Wheatley, David, Earl, Graeme; id_orcid   +3 more
core   +1 more source

Re-Articulating the boundaries of architecture: From the ontology of architecture toward the spectrum of architectural disciplines

ARTEKS : Jurnal Teknik Arsitektur
The development of contemporary architecture demonstrates an increasingly intensive degree of interdisciplinary intervention arising from environmental, technological, social, cultural, and artificial intelligence-related issues.
Purnama Salura
doaj   +1 more source

Ageism and psychosocial variables during the COVID-19 pandemic: a scoping review protocol

Geriatrics, Gerontology and Aging, 2021
OBJECTIVE: To map studies that focused on the effects of the coronavirus disease 2019 (COVID-19) pandemic on the mental health, well-being, self-perception of aging, and intergenerational relationships of older adults, and how ageism affected these ...
Ellen Cristine Rocha Cabral Nunes, Gabriela Cipolli, Deusivania Vieira da Silva Falcão   +2 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Pet ownership-related differences in medical and long-term care costs among community-dwelling older Japanese.

PLoS ONE, 2023
This study examined the differences in medical and long-term care costs over 18 months between pet owners and non-owners among community-dwelling older Japanese. Pet ownership data were collected from 460 community-dwelling adults age 65 years and older.
Yu Taniguchi, Yuri Yokoyama, Tomoko Ikeuchi, Seigo Mitsutake, Hiroshi Murayama, Takumi Abe, Satoshi Seino, Hidenori Amano, Mariko Nishi, Yasuhiro Hagiwara, Shoji Shinkai, Akihiko Kitamura, Yoshinori Fujiwara   +12 more
doaj   +1 more source