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Genome analysis of Actinobacillus pleuropneumoniae strain APPFJLYC01 reveals multidrug resistance and high virulence potential. [PDF]
Fang Z +7 more
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Fragile Sites and Minisatellite Repeat Instability
Molecular Genetics and Metabolism, 2000Oliva Handt, Grant R. Sutherland and Robert I. Richards.
Handt, O., Sutherland, G., Richards, R.
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Minisatellite variant repeat (MVR) analysis of the HRAS1 minisatellite locus
ELECTROPHORESIS, 1998AbstractTwo alternative electrophoretic strategies were used to study the internal variation of the HRAS1 minisatellite after minisatellite variant repeat mapping (MVR‐PCR) was carried out. While the use of automated sequencers with fluorescent based technology is ideal for analyzing fragment size, and therefore, for analyzing the repeat number, the ...
A, Vega +3 more
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PCR‐free digital minisatellite tandem repeat genotyping
ELECTROPHORESIS, 2011AbstractWe demonstrated a proof‐of‐concept for novel minisatellite tandem repeat typing, called PCR‐free digital VNTR (variable number tandem repeat) typing, which is composed of three steps: a ligation reaction instead of PCR thermal cycling, magnetic bead‐based solid‐phase capture for purification, and an elongated sample stacking microcapillary ...
Chen, Y Chen, Yuchao +1 more
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Human minisatellites, repeat DNA instability and meiotic recombination
Electrophoresis, 1999Minisatellites include some of the most variable loci in the human genome and are superb for dissecting processes of tandem repeat DNA instability. Single DNA molecule analysis has revealed different mutation processes operating in the soma and germline. Low-level somatic instability results in simple intra-allelic rearrangements.
Jeffreys, AJ +14 more
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Distribution of tandem repeat polymorphism within minisatellite MS621 (D5S110)
Annals of Human Genetics, 1996SummaryThe minisatellite MS621 (D5S110) is a highly polymorphic tandem repeat locus which maps to the distal region of human chromosome 5p. Major repeat unit variants at D5S110 differ not by base substitutions but by differences in the repetition of an 11 bp sequence motif found within each repeat. The two major classes of repeat unit thus contain two (
Armour, JAL, Crosier, M, Jeffreys, AJ
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Minisatellite repeat coding as a digital approach to DNA typing
Nature, 1991Most DNA typing systems used in forensic and legal medicine assay allelic length variation at tandem repetitive DNA regions such as minisatellites. A simple alternative approach that displays patterns of variant repeat units along minisatellite alleles is described here.
Jeffreys, AJ +4 more
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Human minisatellite loci composed of interspersed GGA-GGT triplet repeats
Proceedings of the Royal Society of London. Series B: Biological Sciences, 1995We have isolated two tandemly repeated loci from human DNA which contain long blocks of GGA and GGT trinucleotide repeats. These two repeat unit types, together with other less common variants, are apparently irregularly interspersed along each repeat array.
Armour, JA +4 more
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Biochimie, 1997
Tandemly repetitive DNA sequences are abundantly interspersed in the genome of practically all eukaryotic species studied. The relative occurrence of one type of repetitive sequence and its location in the genome appear to be species specific. A common property of repetitive sequences within the living world is their ability to give rise to variants ...
H, Debrauwere +3 more
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Tandemly repetitive DNA sequences are abundantly interspersed in the genome of practically all eukaryotic species studied. The relative occurrence of one type of repetitive sequence and its location in the genome appear to be species specific. A common property of repetitive sequences within the living world is their ability to give rise to variants ...
H, Debrauwere +3 more
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New method to measure minisatellite variant repeat variation in population genetic studies
American Journal of Human Biology, 2002AbstractThe classical analysis of minisatellite variant repeat (MVR) variation using modular structures is limited by the lack of knowledge of the mutational process involved in the evolution of most of the minisatellites. In this study a new method to measure MVR variation and to calculate genetic distances using MVR codes is proposed.
M, Brión +4 more
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