Results 41 to 50 of about 3,637 (191)

Molecular characterization of Coxiella burnetii isolates by infrequent restriction site-PCR and MLVA typing

BMC Microbiology, 2006
Background Coxiella burnetii, the causative agent of Q fever, has a wide host range. Few epidemiological tools are available, and they are often expensive or not easily standardized across laboratories. In this work, C.
Meyer Hermann, Souriau Armel, Bodier Christelle C, Frangoulidis Dimitrios, Bejaoui Awatef, Hauck Yolande, Arricau-Bouvery Nathalie, Neubauer Heinrich, Rodolakis Annie, Vergnaud Gilles   +9 more
doaj   +1 more source

Unfolding of quadruplex structure in the G-rich strand of the minisatellite repeat by the binding protein UP1 [PDF]

Proceedings of the National Academy of Sciences, 2002
The mouse hypervariable minisatellite (MN) Pc-1 consists of tandem repeats of d(GGCAG) and flanked sequences. We have previously demonstrated that single-stranded d(GGCAG) n folds into the intramolecular folded-back quadruplex structure under physiological conditions.
Hirokazu, Fukuda, Masato, Katahira, Naoto, Tsuchiya, Yoshiaki, Enokizono, Takashi, Sugimura, Minako, Nagao, Hitoshi, Nakagama   +6 more
openaire   +2 more sources

Technologies for engineering repetitive DNA

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley   +1 more source

MNS16A tandem repeats minisatellite of human telomerase gene: a risk factor for colorectal cancer [PDF]

Carcinogenesis, 2011
Telomerase reactivation and expression of human telomerase gene [human telomerase reverse transcriptase (hTERT)] are hallmarks of unlimited proliferation potential of cancer cells. A polymorphic tandem repeats minisatellite of hTERT gene, termed MNS16A was reported to influence hTERT expression.
Hofer, Philipp, Baierl, Andreas, Feik, Elisabeth, Führlinger, Gerhard, Leeb, Gernot, Mach, Karl, Holzmann, Klaus, Miksche, Michael, Gsur, Andrea   +8 more
openaire   +3 more sources

First Results of a New Inversion Tool for Thermospheric Neutral Mass Density Computations During Severe Geomagnetic Storms

AGU Advances, Volume 7, Issue 3, June 2026.
Abstract In Low Earth Orbit (LEO), atmospheric drag is the dominant source of trajectory prediction error below approximately 700 km altitude, primarily due to inaccuracies in thermospheric density models. This work presents a method for temporally deconvolving Energy Dissipation Rates (EDRs) to produce single‐satellite density estimates, which can be ...
S. Mutschler, M. Pilinski, E. Zesta, D. M. Oliveira, K. Delano, K. Garcia‐Sage, W. K. Tobiska   +6 more
wiley   +1 more source

Tandem repeat copy-number variation in protein-coding regions of human genes

, 2005
BACKGROUND: Tandem repeat variation in protein-coding regions will alter protein length and may introduce frameshifts. Tandem repeat variants are associated with variation in pathogenicity in bacteria and with human disease.
O'Dushlaine, Colm T., Edwards, Richard, Park, Stephen D., Richard J Edwards, Colm T O'Dushlaine, Denis C Shields, Shields, Denis C., Stephen D Park   +7 more
core   +1 more source

Terminal Restriction Fragments (TRF) Method to Analyze Telomere Lengths

Bio-Protocol, 2015
Chromosome ends - telomeres - are a focus of intensive research due to their importance for the maintenance of chromosome stability. Their shortening due to incomplete replication functions as a molecular clock counting the number of cell divisions, and ...
Miloslava Fojtová, Petr Fajkus, Pavla Polanská, Jiří Fajkus   +3 more
doaj   +1 more source

Structural characterization of supercoiled DNA containing a minisatellite repeat that has polypurine/polypyrimidine stretch [PDF]

Nucleic Acids Symposium Series, 2007
The pUC19 derivative pAL79 contains six tandem repeats of a 30-bp unit sequence. Supercoiled pAL79 molecules show aberrant electrophoretic mobility under acidic conditions, and microscopic analysis suggests pAL79 molecules conform to tight plectonemes when deposited on a substrate under acidic conditions.
Mikio, Kato, Takeshi, Haku, Takeshi, Yamauchi, Shigeru, Sugiyama, Kuniaki, Nagayama, Nobuyoshi, Shimizu   +5 more
openaire   +2 more sources

Genetic Estimates of Relatedness: Established Practices and New Opportunities Through Low Coverage Whole‐Genome Sequencing

Molecular Ecology, Volume 35, Issue 11, June 2026.
ABSTRACT Identifying close relatives in wild animal populations is fundamental across many research fields. Genetic estimates of relatedness have expanded rapidly in recent decades, drawing on a range of genetic data types. Here, we review their use and outline opportunities for future studies by combining two complementary approaches.
Annika Freudiger, Natalie Kestel, Vladimir M. Jovanovic, Mariana Madruga de Brito, Angelina V. Ruiz‐Lambides, Katja Nowick, Anja Widdig, Harald Ringbauer   +7 more
wiley   +1 more source

The architecture of the Plasmodiophora brassicae nuclear and mitochondrial genomes

Scientific Reports, 2019
Plasmodiophora brassicae is a soil-borne pathogen that attacks roots of cruciferous plants causing clubroot disease. The pathogen belongs to the Plasmodiophorida order in Phytomyxea. Here we used long-read SMRT technology to clarify the P.
Suzana Stjelja, Johan Fogelqvist, Christian Tellgren-Roth, Christina Dixelius   +3 more
doaj   +1 more source