Results 31 to 40 of about 762,553 (199)

Comparative Sequence Analysis of Human Minisatellites Showing Meiotic Repeat Instability [PDF]

Genome Research, 1999
The highly variable human minisatellites MS32 (D1S8), MS31A (D7S21), and CEB1 (D2S90) all show recombination-based repeat instability restricted to the germline. Mutation usually results in polar interallelic conversion or occasionally in crossovers, which, at MS32 at least, extend into DNA flanking the repeat array, defining a localized recombination ...
Murray, John, Buard, Jérôme, Neil, David L., Yeramian, Edouard, Tamaki, Keiji, Hollies, Caroline, Jeffreys, Alec J.   +6 more
openaire   +3 more sources

Predicting human minisatellite polymorphism. [PDF]

, 2003
International audienceWe seek to define sequence-based predictive criteria to identify polymorphic and hypermutable minisatellites in the human genome.
Benson, Gary, Denoeud, France, Vergnaud, Gilles   +2 more
core   +4 more sources

A human minisatellite hosts an alternative transcription start site for NPRL3 driving its expression in a repeat number‐dependent manner

Human Mutation, 2020
Minisatellites, also called variable number of tandem repeats (VNTRs), are a class of repetitive elements that may affect gene expression at multiple levels and have been correlated to disease.
M. Bertuzzi, Dave T. P. Tang, R. Calligaris, Christina Vlachouli, S. Finaurini, R. Sanges, S. Goldwurm, Mauro Catalan, L. Antonutti, P. Manganotti, G. Pizzolato, G. Pezzoli, F. Persichetti, Piero Carninci, S. Gustincich   +14 more
semanticscholar   +1 more source

Germline mutation rate in the hypervariable minisatellite CEB1 in the parents of children with leukaemia

, 2007
Gardner and colleagues advanced the hypothesis that the Seascale leukaemia cluster may have been caused by germ cell mutagenesis due parental preconceptional irradiation (PPI) of fathers working at the Sellafield nuclear installation. Recent evidence has
G.M. Taylor (7583291), T.O.B. Eden (7583288), J.M. Birch (7583285), M. Reeves (6423854), Yuri E. Dubrova (7580975), B.G. Davies (7583282)   +5 more
core   +5 more sources

Genetic association study of selected candidate genes (ApoB, LPL, Leptin) and telomere length in obese and hypertensive individuals

BMC Medical Genetics, 2009
Background A genetic study was carried out among obese and hypertensive individuals from India to assess allelic association, if any, at three candidate loci: Apolipoprotein B (ApoB) minisatellite and two tetranucleotide repeat loci; LPL (Lipoprotein ...
Saini Divyalakshmi, Pawar Nilambari, Das Birajalaxmi, Seshadri M   +3 more
doaj   +1 more source

Estimation of genetic diversity and population genetic structure in Gymnema sylvestre (Retz.) R. Br. ex Schult. populations using DAMD and ISSR markers

Journal of Genetic Engineering and Biotechnology, 2023
Background Gymnema sylvestre (Retz.) R. Br. ex Schult. is a well-known medicinal plant against diabetes in India. There is as such no organized cultivation in India, and the plant is still being collected from the wild for their therapeutic uses.
Kanchana Vaishnav, Vandana Tiwari, Anjala Durgapal, Baleshwar Meena, T. S. Rana   +4 more
doaj   +1 more source

Genome-Wide Distribution of Novel Ta-3A1 Mini-Satellite Repeats and Its Use for Chromosome Identification in Wheat and Related Species

Agronomy, 2019
A large proportion of the genomes of grasses is comprised of tandem repeats (TRs), which include satellite DNA. A mini-satellite DNA sequence with a length of 44 bp, named Ta-3A1, was found to be highly accumulated in wheat genome, as revealed by a ...
Tao Lang, Guangrong Li, Zhihui Yu, Jiwei Ma, Qiheng Chen, Ennian Yang, Zujun Yang   +6 more
doaj   +1 more source

Extremely Complex Repeat Shuffling during Germline Mutation at Human Minisatellite B6.7 [PDF]

Human Molecular Genetics, 1999
Human minisatellite B6.7 is a highly variable locus showing extensive heterozygosity with alleles ranging from six to >500 repeat units. Paternal and maternal mutation rates to new length alleles were estimated from pedigrees at 7.0 and 3.9% per gamete, respectively, indicating that B6.7 is one of the most unstable minisatellites isolated to date ...
Tamaki, K, May, CA, Dubrova, YE, Jeffreys, AJ   +3 more
openaire   +3 more sources

The nature of minisatellite repeats at four genetic loci.

, 2012
The nature of minisatellite repeats at four genetic loci.
Meng Qi (142397), Guanghui Zhao (142408), Yaoyu Feng (142393), Longxian Zhang (142384), Aiqin Liu (142389), Rongjun Wang (142378), Fuchun Jian (142381), Chaochao Lv (142404), Changshen Ning (142387), Jinfeng Zhao (142391), Helei Wang (142400), Lihua Xiao (142413)   +11 more
core   +1 more source

ProRepeat: an integrated repository for studying amino acid tandem repeats in proteins [PDF]

, 2011
ProRepeat (http://prorepeat.bioinformatics.nl/) is an integrated curated repository and analysis platform for in-depth research on the biological characteristics of amino acid tandem repeats.
Harm Nijveen, Lin, K., Jack A. M. Leunissen, K. Lin, Audrey David, Luo, H., Ke Lin, A. David, David, A., H. Nijveen, H. Luo, Leunissen, J.A.M., Nijveen, H., Hong Luo, J. A. M. Leunissen   +14 more
core   +1 more source