Results 21 to 30 of about 30,003 (256)

DNA barcoded peptide-MHC multimers to measure and monitor minor histocompatibility antigen-specific T cells after allogeneic stem cell transplantation [PDF]

Journal for ImmunoTherapy of Cancer
Allogeneic stem cell transplantation (alloSCT) provides a curative treatment option for hematological malignancies. After HLA-matched alloSCT, donor-derived T cells recognize minor histocompatibility antigens (MiHAs), which are polymorphic peptides ...
Sine R Hadrup, Marieke Griffioen, J H Frederik Falkenburg, Mirjam H M Heemskerk, Marian van de Meent, Michel G D Kester, Kyra J Fuchs, Marcus Göransson, Natasja W Ettienne, Rob C M de Jong, Eva A S Koster, Constantijn J M Halkes, Ferenc Scheeren, Peter van Balen   +13 more
doaj   +2 more sources

Prolonged Skin Graft Survival and Histocompatibility in Highly Inbred Miniature Swine [PDF]

Transplantation Direct
Background. Pigs are potential organ donors for humans. Some proposed xenotransplant tolerance regimens require genetically identical cells from different animals (eg, juvenile bone marrow and mature organs or tissues).
Elin Manell, DVM, PhD, Harko Mulder, MSc, J. Scott Arn, BS, Esad Gunes, MD, Ishit Chauhan, MD, Satyajit Patwardhan, MD, Julie Hong, MD, Ibrahim Batal, MD, David H. Sachs, MD, Joshua Weiner, MD   +9 more
doaj   +2 more sources

Involvement of Male-Specific Minor Histocompatibility Antigen H-Y in Epidermal Equivalent Allograft Rejection

Cell Transplantation, 1998
This study describes the involvement of male-specific minor histocompatibility antigen H-Y in vitro cultured epidermal equivalent (EE) rejection. Male and female Balb/c or C3H/HeN keratinocytes were isolated and cultured separately.
Marie-Josée Beaulieu, Hui Li, Julie Bergeron, Geneviève Ross, François A. Auger, Mahmoud Rouabhia   +5 more
doaj   +2 more sources

The genetic origin of minor histocompatibility antigens

Immunogenetics, 1993
The purpose of this study was to elucidate the genetic origin of minor histocompatibility (H) antigens. Toward this end common inbred mouse strains, distinct subspecies, and species of the subgenus Mus were examined for expression of various minor H antigens.
Roopenian, D C, Christianson, G J, Davis, A P, Zuberi, A R, Mobraaten, L E   +4 more
openaire   +4 more sources

Identification of mimotopes for the H4 minor histocompatibility antigen [PDF]

International Immunology, 1998
The H4 minor histocompatibility antigen (HA) of mice includes a single immunogenic peptide presented by H-2Kb molecules that stimulates skin allograft rejection and is immunodominant in the stimulation of cytolytic T lymphocytes (CTL) specific for multiple minor HA.
Strausbauch, M A, Nevala, W K, Roopenian, D C, Stefanski, H E, Wettstein, P J   +4 more
openaire   +3 more sources

Human minor histocompatibility antigens

Transplant Immunology, 1993
For over five decades minor histocompatibility (mH) antigens have contmued to fascmate immimologists, mainly because of their minor but distinct role in transplantation but no less because of their as yet unknown nature In the 1970s lt became evident that mH antigens were recognized in a MHC restncted fashion, an important feature which was poorly ...
M, de Bueger, E, Goulmy
  +8 more sources

Prognostic significance of tumor microenvironment assessed by machine learning algorithm in surgically resected non‐small cell lung cancer

Cancer Reports, EarlyView., 2023
Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada, Mitsuhiro Isaka, Akira Ono, Takuya Kawata, Masakuni Serizawa, Keita Mori, Koji Muramatsu, Kiyoshi Tone, Hirotsugu Kenmotsu, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Masatoshi Kusuhara, Yasuto Akiyama, Takashi Sugino, Toshiaki Takahashi, Yasuhisa Ohde   +16 more
wiley   +1 more source

Interaction of vascular endothelial cells with CD8+ T-cells in vivo [PDF]

, 2008
Transplantation of organs and cells saves and prolongs thousands of lives every year. Surgical techniques were significantly improved but major problems remain, in particular the host’s immune system.
Bolinger, Beatrice
core   +1 more source

Endothelial cells as targets for antigen-specific cytotoxic T lymphocytes [PDF]

, 2010
BACKGROUND: In this study we have examined human vascular endothelial cells as targets for antigen-specific cytotoxic T lymphocytes (CTL). Vascular endothelial cells (EC) act as the major interface between blood and tissues and are crucial for the ...
Thommen, Daniela Stefanie
core   +1 more source

Molecular modeling of an antigenic complex between a viral peptide and a class I major histocompatibility glycoprotein [PDF]

, 1992
Computer simulation of the conformations of short antigenic peptides (&lo residues) either free or bound to their receptor, the major histocompatibility complex (MHC)- encoded glycoprotein H-2 Ld, was employed to explain experimentally determined ...
Reddehase, Matthias J., Rognan, Didier, Koszinowski, Ulrich H., Folkers, Gerd, Gerd Folkers, Didier Rognan, Matthias J. Reddehase, Ulrich H. Koszinowski   +7 more
core   +1 more source