Results 101 to 110 of about 23,101 (249)

Mapping Allergen B‐ and T‐Cell Epitopes: Technological Advances and Their Role in Precision Allergy Therapy

Allergy, EarlyView.
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche, Josefine Corneliussen, Kristoffer H. Johansen, Alexandre Ruiz‐Carrasco, Caroline Paulsen, Yuchen Li, Carolina Barra, Sandhya Bangaru, Monica L. Fernández‐Quintero, Ewa Bartko, Lars Blom, Esperanza Rivera‐de‐Torre   +11 more
wiley   +1 more source

Shared graft-versus-leukemia minor histocompatibility antigens in DISCOVeRY-BMT. [PDF]

Blood Adv, 2023
Olsen KS, Jadi O, Dexheimer S, Bortone DS, Vensko SP, Bennett S, Tang H, Diiorio M, Saran T, Dingfelder D, Zhu Q, Wang Y, Haiman CA, Pooler L, Sheng X, Webb A, Pasquini MC, McCarthy PL, Spellman SR, Weimer E, Hahn T, Sucheston-Campbell L, Armistead PM, Vincent BG.   +23 more
europepmc   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Estudio de la compatibilidad por métodos serológicos (HLA) y celulares (CML) en 22 años de trabajo en el Instituto de Hematología e Inmunología Compatibility study by serological (HLA) and cellular methods (MLC) during 22 years of work at the Institute of Hematology and Immunology

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2003
Se estudió la histocompatibilidad de los loci ABC y del locus D del sistema principal de histocompatibilidad mediante las técnicas serológicas de microlinfocitotoxicidad en 383 pacientes con diferentes enfermedades hematológicas.
Luz M Morera Barrios, Catalino R Ustáriz García, Ana M Guerreiro Hernández, Lázaro O del Valle Pérez, Consuelo Macías Abraham, Marta Paradoa Pérez, Elvira Dorticós Balea   +6 more
doaj  

Associations of minor histocompatibility antigens with outcomes following allogeneic hematopoietic cell transplantation. [PDF]

Am J Hematol, 2023
Jadi O, Tang H, Olsen K, Vensko S, Zhu Q, Wang Y, Haiman CA, Pooler L, Sheng X, Brock G, Webb A, Pasquini MC, McCarthy PL, Spellman SR, Hahn T, Vincent B, Armistead P, Sucheston-Campbell LE.   +17 more
europepmc   +1 more source

Characterization and recognition of minor histocompatibility antigens

, 2016
Minor histocompatibility antigens (MiHA) are structures that can be recognized by T cells. In the setting of allogeneic stem cell transplantation MiHA presented by patient cells can be recognized by donor T cells.
Bergen, Cornelis Adrianus Maria van
core  

Cutaneous Acute Graft-Versus-Host Disease to Minor Histocompatibility Antigens in a Murine Model: Histologic Analysis and Correlation to Clinical Disease

, 1986
Graft-versus-host disease (GVHD) can ccur in bone marrow-transplant recipients even when donor and host are identically matched at the major histocompatibility complex.
Sleckman, Barry, Guillen, Francisco J, Burakoff, Steven J, Ferrara, James, Murphy, George F   +4 more
core   +1 more source

MicroRNAs as potential architects of immune dysregulation and megakaryocytic failure in immune thrombocytopenia

British Journal of Haematology, EarlyView.
Summary Immune thrombocytopenia (ITP) is a complex autoimmune disorder characterized by accelerated destruction of peripheral platelets and impaired megakaryopoiesis. While the cellular effectors, dysregulated T cells, hyperactive B cells and phagocytic macrophages are well characterized, the upstream epigenetic mechanisms orchestrating this ...
Zhenyu Liu, Johan Rebetz, Lamya Garabet, Waleed Ghanima, Peipei Xu, Hans Wadenvik, Drew Provan, Rick Kapur, John W. Semple   +8 more
wiley   +1 more source

Toward a network model of MHC class II-restricted antigen processing

Frontiers in Immunology, 2013
The standard model of Major Histocompatibility Complex class II (MHCII)-restricted antigen processing depicts a straightforward, linear pathway: Internalized antigens are converted into peptides that load in a chaperone dependent manner onto nascent ...
Laurence C Eisenlohr, Michael A Miller, Asha Purnima Veerappan Ganesan   +2 more
doaj   +1 more source

Oligoprogressive renal cell carcinoma: What is the role of surgery?

BJU International, EarlyView.
Objective To provide an overview of the biological mechanism and pattern of oligoprogression in renal cell carcinoma (RCC) and the most updated role of surgery in this setting, highlighting scientific gaps and informing future implications. Methods A non‐systematic search of PubMed/MEDLINE was performed in August 2025 including guidelines, reviews, and
Chiara Re, William H.J. Ince, Leo Bickley, James P. Blackmur, Mouhamad H. Ismail, Justicia Kyeremeh, Teele Kuusk, Eva Mendes Serrao, James O. Jones, Grant D. Stewart   +9 more
wiley   +1 more source