Results 81 to 90 of about 861,631 (245)

Composition of allogeneic equine orthobiologics and their repeated intra‐articular administrations

Equine Veterinary Journal, EarlyView.
Abstract Background Orthobiologics such as platelet‐rich plasma (PRP) and alpha‐2‐macroglobulin (A2MG) are increasingly used for equine musculoskeletal injuries. However, their composition and safety with repeated allogeneic intra‐articular administration remain poorly investigated.
Yanne Van Reusel, Sarah Y. Broeckx, Anna Carolo, Marco Patruno, Jonas Steenbrugge, Jimmy Saunders, Enrico Gugliandolo, Jan H. Spaas   +7 more
wiley   +1 more source

Interferon y Stimulation Modulates the Proteolytic Activity and Cleavage Site Preference of 20S Mouse Proteasomes [PDF]

, 1994
The proteasome is a 700-kD multisubunit enzyme complex with several proteolytically active sites. The enzyme complex is involved in both ubiquitin-dependent and -independent protein degradation and may contribute to the processing of antigens presented ...
Multhaupt, Gerd, Koszinowski, Ulrich H., Kloetzel, Peter-M., Boes, Bettina, Ruppert, Thomas, Hengel, Hartmut   +5 more
core   +1 more source

EGR-2 is not required for in vivo CD4 T cell mediated immune responses.

PLoS ONE, 2010
BackgroundThe zinc finger transcription factor EGR-2 has been shown to play an important role in the induction of T cell anergy and the regulation of peripheral T cell tolerance.
Hilda E Ramón, Pedro J Cejas, David LaRosa, Adeeb Rahman, John E Harris, Jidong Zhang, Christopher Hunter, Yongwon Choi, Laurence A Turka   +8 more
doaj   +1 more source

The Human Minor Histocompatibility Antigen1 Is a RhoGAP

PLoS ONE, 2013
The human minor Histocompatibility Antigen HMHA-1 is a major target of immune responses after allogeneic stem cell transplantation applied for the treatment of leukemia and solid tumors. The restriction of its expression to hematopoietic cells and many solid tumors raised questions regarding its cellular functions.
Kreuk, B.J. de, Schaefer, A., Anthony, E.C., Tol, S., Fernandez-Borja, M., Geerts, D., Pool, J., Hambach, L., Goulmy, E., Hordijk, P.L.   +9 more
openaire   +5 more sources

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Estudio de la compatibilidad por métodos serológicos (HLA) y celulares (CML) en 22 años de trabajo en el Instituto de Hematología e Inmunología Study of compatibility by serological(HLA)and cellular methods (MLC) in 22 years of work in the Hematology and Immunology Institute

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2002
Se estudió la histocompatibilidad de los loci ABC y del locus D del sistema principal de histocompatibilidad mediante las técnicas serológicas de microlinfocitotoxicidad en 383 pacientes con diferentes enfermedades hematológicas.
Luz M Morera Barrios, Catalino R Ustáriz García, Ana María Guerreiro Hernández, Lázaro O del Valle Pérez, Consuelo Macías Abraham, Marta Paradoa Pérez, Elvira Dorticós Balea   +6 more
doaj  

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

iMeta, EarlyView.
Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen, Xiaoling Wang, Xiang Liu, Kui Dong, Yanying Feng, Min Yuan, Shiyi Wang, Fangfang Fan, Yong Tian, Zhiming Kang, Xiushuai Du, Chaolu Hasi, Hong Lu, Wei Guan, Xu Chen, Mengyu Cheng, Wei Wei, Nan Guo, Zhiguo Liu, Xiaotong Qiu, Yiwei Shi, Kun Xiao, Yi Wang, Zhenjun Li   +23 more
wiley   +1 more source

The Expression of Sex-Specific and Autosomal Minor Histocompatibility Antigens by the Placenta

, 2013
Full text is available to authenticated members of The University of Auckland only.Introduction: Minor histocompatibility antigens were identified as causing organ transplant rejection in HLAmatched donor/recipient pairs (1).
Gamage, Teena
core  

A Physical Map Including a New Class I Gene (cda12) of the Human Major Histocompatibility Complex (A2/313 Haplotype) Derived from a Monosomy 6 Mutant Cell Line [PDF]

, 1989
To avoid interpretative problems due to restriction fragment length polymorphisms, the monosomy 6 mutant cell line BM19.7 was employed to establish a molecular map of the human major histocompatibility (HLA) complex in the A2,B13,Bw4,DRw6,DRw52,DQw1,DPw2
Pohla, Heike, Bloemer, K, Messer, Gerald, Bloemer, Katharina, Messer, G, Ziegler, Andreas, Ragoussis, Jiannis, Ragoussis, J, Weiss, Elisabeth H., Pohla, H, Weiss, EH, Ziegler, A   +11 more
core   +1 more source

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source