Development of a sample bank and clinical database for the retrospective analysis of unrelated bone marrow transplants: a pilot study of 138 transplants using RSCA for high resolution HLA matching. [PDF]
The Anthony Nolan Register provides donors for allogeneic stem cell transplantation for haematological disorders. A clinical database and sample bank were established for the ongoing analysis of transplants from Register donors.
Pay, A.L.P.
core
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao +4 more
wiley +1 more source
Minor H antigens: genes and peptides [PDF]
In this review, we describe the evidence from which the existence of non-MHC histocompatibility (H) antigens was deduced, the clinical setting of bone marrow transplantation in which they are important targets for T-cell responses, and the current ...
D. Scott +15 more
core +1 more source
DataSheet_1_A Model of Minor Histocompatibility Antigens in Allogeneic Hematopoietic Cell Transplantation.xlsx [PDF]
Minor histocompatibility antigens (mHAg) composed of peptides presented by HLA molecules can cause immune responses involved in graft-versus-host disease (GVHD) and graft-versus-leukemia effects after allogeneic hematopoietic cell transplantation (HCT ...
Daniel E. Geraghty (7456205) +11 more
core +1 more source
Prophylactic approaches to graft versus host disease (GvHD) have employed both phenotypic reduction of T cells and selective elimination of host-primed donor T cells in vitro and in vivo.
Shai eYarkoni +3 more
doaj +1 more source
Identification of mimotopes for the H4 minor histocompatibility antigen [PDF]
The H4 minor histocompatibility antigen (HA) of mice includes a single immunogenic peptide presented by H-2Kb molecules that stimulates skin allograft rejection and is immunodominant in the stimulation of cytolytic T lymphocytes (CTL) specific for multiple minor HA.
Strausbauch, M A +4 more
openaire +2 more sources
IMMUNOBIOLOGY OF ACUTE GRAFT-VERSUS-HOST DISEASE
Transplantation of allogeneic hematopoietic stem cells is the only curative option for a number of diseases of hematopoietic system. It is intended to replace the hematopoietic system of the recipient withthe donor’s.
G. A. Efimov +5 more
doaj +1 more source
Composition of allogeneic equine orthobiologics and their repeated intra‐articular administrations
Abstract Background Orthobiologics such as platelet‐rich plasma (PRP) and alpha‐2‐macroglobulin (A2MG) are increasingly used for equine musculoskeletal injuries. However, their composition and safety with repeated allogeneic intra‐articular administration remain poorly investigated.
Yanne Van Reusel +7 more
wiley +1 more source
Characterization and recognition of minor histocompatibility antigens [PDF]
Minor histocompatibility antigens (MiHA) are structures that can be recognized by T cells. In the setting of allogeneic stem cell transplantation MiHA presented by patient cells can be recognized by donor T cells.
Bergen, Cornelis Adrianus Maria van
core +1 more source
Cutaneous Acute Graft-Versus-Host Disease to Minor Histocompatibility Antigens in a Murine Model: Histologic Analysis and Correlation to Clinical Disease [PDF]
Graft-versus-host disease (GVHD) can ccur in bone marrow-transplant recipients even when donor and host are identically matched at the major histocompatibility complex.
Sleckman, Barry +4 more
core +1 more source

