Results 11 to 20 of about 23,170 (228)

Phenotype frequencies of autosomal minor histocompatibility antigens display significant differences among populations. [PDF]

PLoS Genetics, 2007
Minor histocompatibility (H) antigens are allogeneic target molecules having significant roles in alloimmune responses after human leukocyte antigen-matched solid organ and stem cell transplantation (SCT).
Eric Spierings, Matthijs Hendriks, Léna Absi, Angelica Canossi, Sonal Chhaya, John Crowley, Harry Dolstra, Jean-François Eliaou, Tom Ellis, Jürgen Enczmann, Maria E Fasano, Thibaut Gervais, Clara Gorodezky, Brigitte Kircher, David Laurin, Mary S Leffell, Pascale Loiseau, Mari Malkki, Miroslaw Markiewicz, Miryam Martinetti, Etsuko Maruya, Narinder Mehra, Fatma Oguz, Machteld Oudshoorn, Noemi Pereira, Rajni Rani, Ruhena Sergeant, Jackie Thomson, Thuong Hien Tran, Hannu Turpeinen, Kuo-Liang Yang, Renata Zunec, Mary Carrington, Peter de Knijff, Els Goulmy   +34 more
doaj   +5 more sources

Minor histocompatibility antigens [PDF]

Current Opinion in Immunology, 1997
The existence of transplantation antigens, in addition to those encoded by genes in the MHC, has been known for over half a century. The molecular identification of these additional minor histocompatibility (H) antigens lagged behind that of their MHC counterparts, largely because minor H antigens are recognised by T cells and not by antibodies. In the
Simpson, E, Roopenian, D C
core   +4 more sources

The immunogenomics of minor histocompatibility antigens [PDF]

Immunological Reviews, 2002
Summary: Minor histocompatibility (H) antigens are a diverse assemblage of major histocompatibility complex (MHC)‐bound peptides with the unifying property of acting as alloantigens that induce allogeneic tissue rejection. They are a consequence of any form of accumulated genetic variation that translates to differential MHC‐presented peptide epitopes,
Roopenian, D, Choi, E Y, Brown, A
openaire   +4 more sources

Minor Histocompatibility Antigens in GVL [PDF]

, 2000
In syngeneic bone marrow transplantation (BMT) and in recipients of autologous BMT, relapse rates are high. No MHC or minor histocompatibility antigen (mHag) disparities exist and thus no alloreactivities can be induced. This is clearly different in allogeneic BMT, where the relapse rates are significantly lower and a relationship is seen between the ...
Mutis, Tuna, Goulmy, Els
core   +7 more sources

The genetic origin of minor histocompatibility antigens [PDF]

Immunogenetics, 1993
The purpose of this study was to elucidate the genetic origin of minor histocompatibility (H) antigens. Toward this end common inbred mouse strains, distinct subspecies, and species of the subgenus Mus were examined for expression of various minor H antigens.
Roopenian, D C, Christianson, G J, Davis, A P, Zuberi, A R, Mobraaten, L E   +4 more
openaire   +4 more sources

High-throughput identification of potential minor histocompatibility antigens by MHC tetramer-based screening: feasibility and limitations. [PDF]

PLoS ONE, 2011
T-cell recognition of minor histocompatibility antigens (MiHA) plays an important role in the graft-versus-tumor (GVT) effect of allogeneic stem cell transplantation (allo-SCT).
Pleun Hombrink, Sine R Hadrup, Arne Bakker, Michel G D Kester, J H Frederik Falkenburg, Peter A von dem Borne, Ton N M Schumacher, Mirjam H M Heemskerk   +7 more
doaj   +2 more sources

A uniform genomic minor histocompatibility antigen typing methodology and database designed to facilitate clinical applications. [PDF]

PLoS ONE, 2006
BACKGROUND: Minor Histocompatibility (H) antigen mismatches significantly influence the outcome of HLA-matched allogeneic stem cell transplantation. The molecular identification of human H antigens is increasing rapidly. In parallel, clinical application
Eric Spierings, Jos Drabbels, Matthijs Hendriks, Jos Pool, Marijke Spruyt-Gerritse, Frans Claas, Els Goulmy   +6 more
doaj   +4 more sources

The Connection Between Minor H Antigens and Neoantigens and the Missing Link in Their Prediction [PDF]

Frontiers in Immunology, 2020
For hundreds of thousands of years, the human genome has extensively evolved, resulting in genetic variations in almost every gene. Immunological reflections of these genetic variations become clearly visible after an allogeneic stem cell transplantation
Tuna Mutis, Anastasia Xagara, Anastasia Xagara, Robbert M. Spaapen, Robbert M. Spaapen   +4 more
doaj   +2 more sources

Prolonged Skin Graft Survival and Histocompatibility in Highly Inbred Miniature Swine [PDF]

Transplantation Direct
Background. Pigs are potential organ donors for humans. Some proposed xenotransplant tolerance regimens require genetically identical cells from different animals (eg, juvenile bone marrow and mature organs or tissues).
Elin Manell, DVM, PhD, Harko Mulder, MSc, J. Scott Arn, BS, Esad Gunes, MD, Ishit Chauhan, MD, Satyajit Patwardhan, MD, Julie Hong, MD, Ibrahim Batal, MD, David H. Sachs, MD, Joshua Weiner, MD   +9 more
doaj   +2 more sources

Antibody-mediated rejection of transplanted kidney associated with anti-Jka alloantibodies: An interesting case report with review of literature [PDF]

Asian Journal of Transfusion Science
There is increasing evidence for renal expression of non-ABO minor blood group antigens on the renal endothelium of the vasa recta and tubular epithelial cells.
Rasika Dhawan Setia, Mitu Dogra, Rajan Duggal, Vishal Saxena, Jasbir Singh, Anil Handoo   +5 more
doaj   +2 more sources