Results 21 to 30 of about 23,101 (249)

Minor histocompatibility antigens are expressed in syncytiotrophoblast and trophoblast debris: implications for maternal alloreactivity to the fetus. [PDF]

Am J Pathol, 2012
The fetal semi-allograft can induce expansion and tolerance of antigen-specific maternal T and B cells through paternally inherited major histocompatibility complex and minor histocompatibility antigens (mHAgs).
Holland OJ, Linscheid C, Hodes HC, Nauser TL, Gilliam M, Stone P, Chamley LW, Petroff MG.   +7 more
europepmc   +2 more sources

Minor Histocompatibility Antigens and the Maternal Immune Response to the Fetus During Pregnancy [PDF]

American Journal of Reproductive Immunology, 2013
Margaret G Petroff
exaly   +2 more sources

Natural regulation of immunity to minor histocompatibility antigens. [PDF]

The Journal of Immunology, 2007
MHC-matched hemopoietic stem cell transplantation is commonly used for the treatment of some forms of leukemia. Conditioning regimens before transplant act to reduce the burden of leukemic cells and the graft-vs-leukemia (GvL) effect can eliminate ...
Robertson, Nathan J, Lemonnier, François, Dyson, Julian, Manktelow, Emily, Hashim, Fazila, Scott, Diane, Simpson, Elizabeth, Millrain, Maggie, Chai, Jian-Guo   +8 more
core   +4 more sources

Exploiting T cells specific for human minor histocompatibility antigens for therapy of leukemia [PDF]

Immunology and Cell Biology, 2011
Marie Bleakley
exaly   +2 more sources

Minor Histocompatibility Antigen-Specific T Cells

Frontiers in Pediatrics, 2020
Minor Histocompatibility (H) antigens are major histocompatibility complex (MHC)/Human Leukocyte Antigen (HLA)-bound peptides that differ between allogeneic hematopoietic stem cell transplantation (HCT) recipients and their donors as a result of genetic ...
Corinne Summers, Corinne Summers, Vipul S. Sheth, Marie Bleakley, Marie Bleakley   +4 more
doaj   +1 more source

T-Cell Immunotherapies Targeting Histocompatibility and Tumor Antigens in Hematological Malignancies

Frontiers in Immunology, 2020
Over the last decades, T-cell immunotherapy has revealed itself as a powerful, and often curative, strategy to treat blood cancers. In hematopoietic cell transplantation, most of the so-called graft-vs.-leukemia (GVL) effect hinges on the recognition of ...
Valérie Janelle, Caroline Rulleau, Simon Del Testa, Cédric Carli, Jean-Sébastien Delisle, Jean-Sébastien Delisle, Jean-Sébastien Delisle   +6 more
doaj   +1 more source

Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase

Frontiers in Immunology, 2020
Minor histocompatibility antigens are the main targets of donor-derived T-cells after allogeneic stem cell transplantation. Identification of these antigens and understanding their biology are a key requisite for more insight into how graft vs.
Anita N. Kremer, Judith Bausenwein, Ellie Lurvink, Andreas E. Kremer, Caroline E. Rutten, Cornelis A. M. van Bergen, Sascha Kretschmann, Edith van der Meijden, Maria W. Honders, Daniela Mazzeo, Colin Watts, Andreas Mackensen, J. H. Frederik Falkenburg, Marieke Griffioen   +13 more
doaj   +1 more source

Prognostic significance of tumor microenvironment assessed by machine learning algorithm in surgically resected non‐small cell lung cancer

Cancer Reports, EarlyView., 2023
Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada, Mitsuhiro Isaka, Akira Ono, Takuya Kawata, Masakuni Serizawa, Keita Mori, Koji Muramatsu, Kiyoshi Tone, Hirotsugu Kenmotsu, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Masatoshi Kusuhara, Yasuto Akiyama, Takashi Sugino, Toshiaki Takahashi, Yasuhisa Ohde   +16 more
wiley   +1 more source

Human minor histocompatibility antigens

Transplant Immunology, 1993
For over five decades minor histocompatibility (mH) antigens have contmued to fascmate immimologists, mainly because of their minor but distinct role in transplantation but no less because of their as yet unknown nature In the 1970s lt became evident that mH antigens were recognized in a MHC restncted fashion, an important feature which was poorly ...
M, de Bueger, E, Goulmy
openaire   +5 more sources

HapMap scanning of novel human minor histocompatibility antigens

Blood, 2009
Michi Kamei, Hiroki Torikai, Kunio Tsujimura   +2 more
exaly   +2 more sources