Cytomegalovirus prevents antigen presentation by blocking the transport of peptide-loaded major histocompatibility complex class I molecules into the medial-Golgi compartment [PDF]
Selective expression of murine cytomegalovirus (MCMV) immediate-early (IE) genes leads to the presentation by the major histocompatibility complex (MHC) class I molecule L a of a peptide derived from MCMV IE protein pp89 (Reddehase, M. J., J.
Koszinowski, Ulrich H. +13 more
core +1 more source
Cell-based therapy in prophylaxis and treatment of chronic graft-versus-host disease
Hematopoietic allogeneic stem cell transplantation (allo-SCT) is a curative option for patients with hematological malignancies. However, due to disparities in major and minor histocompatibility antigens between donor and recipient, severe inflammatory ...
Matteo Doglio +13 more
doaj +1 more source
In rodents, immune responses to minor histocompatibility antigens are the most important drivers of corneal graft rejection. However, this has not been confirmed in humans or in a large animal model and the genetic loci are poorly characterised, even in ...
Susan Nicholls +6 more
doaj +1 more source
Molecular modeling of an antigenic complex between a viral peptide and a class I major histocompatibility glycoprotein [PDF]
Computer simulation of the conformations of short antigenic peptides (&lo residues) either free or bound to their receptor, the major histocompatibility complex (MHC)- encoded glycoprotein H-2 Ld, was employed to explain experimentally determined ...
Reddehase, Matthias J. +7 more
core +1 more source
Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules [PDF]
Major histocompatibility complex (MHC) class II molecules are transported to intracellular MHC class II compartments via a transient association with the invariant chain (Ii).
Pieters, J. +11 more
core +1 more source
HLA class I-restricted minor histocompatibility antigens.
HLA class I-restricted minor histocompatibility antigens.
Marieke Griffioen (119817) +3 more
core +1 more source
Hematopoietic cell (HC) transplantation (HCT) is the last resort to cure hematopoietic malignancies that are refractory to standard therapies. Hematoablative treatment aims at wiping out tumor cells as completely as possible to avoid leukemia/lymphoma ...
Matthias J. Reddehase +2 more
doaj +1 more source
In silico analysis of minor histocompatibility antigens.
In silico analysis of minor histocompatibility antigens.
Marieke Griffioen (119817) +3 more
core +1 more source
The bone marrow transplantation (BMT) between haplo-identical combinations (haploBMT) could cause unacceptable bone marrow graft rejection and graft-versus-host disease (GVHD).
Hisanori Mayumi
doaj +1 more source
Immunological basis of differences in disease resistance in the chicken [PDF]
Genetic resistance to diseases is a multigenic trait governed mainly by the immune system and its interactions with many physiologic and environmental factors.
Rebel, J.M.J. +5 more
core +1 more source

