Results 71 to 80 of about 13,606 (275)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The Holy Scriptures in Croatian-Glagolitic Liturgical Codices [PDF]

open access: yes, 1985
Father Josip Tandarić, Zagreb, JugoslavijaIn this Serbo-Croatian article, Tandarić compares the texts of several pericopes from the Old and New Testament in Croatian Glagolitic manuscripts. At the end of the article, Tandarić summarizes the bibliography
Tandarić, Josip
core  

Tournament minors

open access: yesJournal of Combinatorial Theory, Series B, 2015
We say a digraph $G$ is a {\em minor} of a digraph $H$ if $G$ can be obtained from a subdigraph of $H$ by repeatedly contracting a strongly-connected subdigraph to a vertex. Here, we show the class of all tournaments is a well-quasi-order under minor containment.
Kim, Ilhee, Seymour, Paul
openaire   +3 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Metateatralne elementy dramatów Witkacego

open access: yesPamiętnik Teatralny, 2016
Following in the footsteps of Alf Sjöberg and Krystyna Ruta-Rutkowska, the author of the article finds metatheatrical elements in the plays by Stanisław Ignacy Witkiewicz and by doing so casts doubt on the assertion made by Jan Błoński that it is ...
Przemysław Pawlak
doaj   +1 more source

Ethnography and Ancient History [PDF]

open access: yes, 2013
Se trata de un artículo para una enciclopedia anglosajona donde se explica el surgimiento de la etnografía en la antigua Grecia y su relación con la historia ...
Albaladejo Vivero, Manuel
core  

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