Results 101 to 110 of about 37,458 (290)

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source

Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway

Molecular Cancer, 2017
Background The primary issue arising from prostate cancer (PCa) is its high prevalence to metastasize to bone, which severely affects the quality of life and survival time of PCa patients.
Dong Ren, Qing Yang, Yuhu Dai, Wei Guo, Hong Du, Libing Song, Xinsheng Peng   +6 more
doaj   +1 more source

miR-210-3p suppresses osteogenic differentiation of MC3T3-E1 by targeting brain derived neurotrophic factor (BDNF)

Journal of Orthopaedic Surgery and Research, 2022
Background and objective As an important mediator of intercellular interaction and formation of extracellular bone matrix, porous scaffolds are widely used for bone regeneration.
Li Deng, Shuang Lai, Liyuan Fan, Xinlun Li, Hao Huang, Yandong Mu   +5 more
doaj   +1 more source

Radiological evaluation of biomarkers for renal cell carcinoma [PDF]

, 2018
Role of MRI DWI sequences in the evaluation of early response to neo- angiogenesis inhibitors in metastatic renal cell carcinoma Purpose: Angiogenesis inhibitors have a potential role in treating metastatic renal cell carcinoma, but it is still not ...
Marigliano, Chiara
core   +1 more source

Genistein-induced mir-23b expression inhibits the growth of breast cancer cells [PDF]

, 2015
Aim of the study: Genistein, an isoflavonoid, plays roles in the inhibition of protein tyrosine kinase phosphorylation, induction of apoptosis, and cell differentiation in breast cancer.
Avci, C.B., Aygunes, D., Balci, T., Caglar, H.O., Dodurga, Yavuz, Gunduz, C., Susluer, S.Y.   +6 more
core   +2 more sources

miR-210 promotes IPF fibroblast proliferation in response to hypoxia

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2014
Idiopathic pulmonary fibrosis (IPF) is characterized by the relentless spread of fibroblasts from scarred alveoli into adjacent alveolar units, resulting in progressive hypoxia and death by asphyxiation. Although hypoxia is a prominent clinical feature of IPF, the role of hypoxia as a driver of the progressive fibrotic nature of the disease has not ...
Vidya, Bodempudi, Polla, Hergert, Karen, Smith, Hong, Xia, Jeremy, Herrera, Mark, Peterson, Wajahat, Khalil, Judy, Kahm, Peter B, Bitterman, Craig A, Henke   +9 more
openaire   +3 more sources

Overexpression of miR-210 is Associated with Poor Prognosis of Acute Myeloid Leukemia [PDF]

Medical Science Monitor, 2015
MicroRNAs play important roles in regulation of the initiation and progression of AML. MiR-210 is closely related with cancer development; however, whether miR-210 expression level correlates with clinical correlation in AML is unknown. Thus, the aim of this study was to investigate the potential relationship between miR-210 expression and AML ...
Tang, Xiaoqiong, Chen, Liping, Yan, Xinyu, Li, Yuanjie, Xiong, Yuanlin, Zhou, Xiaohui   +5 more
openaire   +2 more sources

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs, Willie J. Hale, Casey L. Straud, Jim Mintz, Stacey Young‐McCaughan, Kimberly D. Gomes, Chelsea J. Sterne, Katrina M. Lawrence‐Wolff, Alan J. Bartholomew, Kevin M. Kelly, Douglas M. Maurer, Catherine Vriend, Brett T. Litz, Douglas E. Williamson, Alan L. Peterson, for the STRONG STAR Consortium   +15 more
wiley   +1 more source

Simultaneous miRNA and mRNA transcriptome profiling of human myoblasts reveals a novel set of myogenic differentiation-associated miRNAs and their target genes [PDF]

, 2013
Background: miRNA profiling performed in myogenic cells and biopsies from skeletal muscles has previously identified miRNAs involved in myogenesis. Results: Here, we have performed miRNA transcriptome profiling in human affinity-purified CD56+ myoblasts ...
Barat, A, Carnac, G, Dessen, P, Dmitriev, P, Laoudj-Chenivesse, D, Lazar, V, Lipinski, M, O'Connell, MJ, Polesskaya, A, Robert, T, Turki, A, Vassetzky, YS, Walsh, TA   +12 more
core   +5 more sources

Formal and Informal Social Care in People With Rheumatic and Musculoskeletal Diseases: A Cross‐Sectional Multicenter Survey

Arthritis Care &Research, EarlyView.
Objective Rheumatic and musculoskeletal diseases (RMDs) are leading causes of physical disability, necessitating support with activities of daily living. This study describes social care received by patients with RMDs in two disparate regions of England: Salford (urban) and Norfolk (rural).
Mehreen Somro, Karen Durrant, William G. Dixon, John McBeth, Alex MacGregor, Max Yates, Jenny H. Humphreys   +6 more
wiley   +1 more source