Results 81 to 90 of about 482,752 (300)
Potential role of HIF-1-responsive microRNA210/HIF3 axis on gemcitabine resistance in cholangiocarcinoma cells. [PDF]
PLoS ONE, 2018 MicroRNA-210 (miR-210) is a robust target for hypoxia-inducible factor, and its overexpression has been detected in a variety of solid tumors. However, the role of miR-210 in the development, progression and response to therapy in cholangiocarcinoma (CCA)
Runglawan Silakit +11 more
doaj +1 more source
SWIM: A computational tool to unveiling crucial nodes in complex biological networks [PDF]
, 2017 SWItchMiner (SWIM) is a wizard-like software implementation of a procedure, previously described, able to extract information contained in complex networks.
Colombo, Teresa +5 more
core +2 more sources
Arteriosclerosis, Thrombosis and Vascular Biology, 2020 Supplemental Digital Content is available in the text. Objective: Inflammatory activation changes the mitochondrial function of macrophages from oxidative phosphorylation to reactive oxygen species production, which may promote necrotic core formation in
E. Karshovska +9 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2021 Hsa-miR-210-3p has been reported to be upregulated in preeclampsia (PE); however, the functions of miR-210-3p in placental development are not fully understood, and, consequently, miR-210-3p’s role in the pathogenesis of PE is still under investigation ...
Heyam Hayder +5 more
semanticscholar +1 more source
Hypoxia-Induced miR-210 Modulates Tissue Response to Acute Peripheral Ischemia [PDF]
Antioxidants & Redox Signaling, 2014 Peripheral artery disease is caused by the restriction or occlusion of arteries supplying the leg. Better understanding of the molecular mechanisms underpinning tissue response to ischemia is urgently needed to improve therapeutic options. The aim of this study is to investigate hypoxia-induced miR-210 regulation and its role in a mouse model of ...
Zaccagnini, Germana +8 more
openaire +2 more sources
Cellular Physiology and Biochemistry, 2018 Background/Aims: Since the function of microRNA (miR)-210 in non-small cell lung cancer (NSCLC) remains unclear, we aimed to explore the clinical significance of miR-210 in NSCLC.
Rong-quan He +8 more
doaj +1 more source
Malignancy Associated MicroRNA Expression Changes in Canine Mammary Cancer of Different Malignancies [PDF]
, 2014 MicroRNA has been suspected to be generally involved in carcinogenesis since their first description. A first study supported this assumption for canine mammary tumors when miRNA expression was compared to normal gland.
Deetzen, Marie-Charlotte +3 more
core +3 more sources
Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes.
Diabetes, 2021 Red blood cells (RBCs) act as mediators of vascular injury in type 2 diabetes mellitus (T2DM). miR-210 plays a protective role in cardiovascular homeostasis and is decreased in whole blood of T2DM mice.
Zhichao Zhou +17 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2021 Inhalational anaesthetics were previously reported to promote ovarian cancer malignancy, but underlying mechanisms remain unclear. The present study aims to investigate the role of sevoflurane- or desflurane-induced microRNA (miRNA) changes on ovarian ...
Masashi Ishikawa +7 more
semanticscholar +1 more source
Molecular Therapy: Nucleic Acids, 2018 We previously found that 19 microRNAs (miRNAs) significantly increased in the sera of hepatocellular carcinoma (HCC) patients. Here, we evaluated whether these miRNAs were secreted by HCC cells and contributed to tumor angiogenesis. High level of miR-210-
Xue-Jia Lin +6 more
doaj +1 more source