Results 1 to 10 of about 11,229 (247)

CircAGFG1 promotes cervical cancer progression via miR-370-3p/RAF1 signaling [PDF]

open access: yesBMC Cancer, 2019
Background In past decades, circular RNAs (circRNAs) have achieved increasing attention because of its regulatory role in different kinds of cancers. However, how circAGFG1 regulates cervical cancer (CC) is still largely undiscovered.
Fengqin Wu, Jingjing Zhou
doaj   +3 more sources

Recent findings on miR‑370 expression, regulation and functions in cancer (Review). [PDF]

open access: yesOncol Rep, 2023
MicroRNAs (miRNAs/miRs) are a group of small non‑coding RNAs that serve as post‑transcriptional gene modulators. miRNAs have been demonstrated to serve a pivotal role in carcinogenesis and the dysregulated expression of miRNAs is a well‑understood characteristic of cancer. In recent years, miR‑370 has been established as a key miRNA in various cancers.
Ye L   +8 more
europepmc   +3 more sources

[Corrigendum] miR‑370 regulates cell proliferation and migration by targeting EGFR in gastric cancer. [PDF]

open access: yesOncol Rep, 2022
Epidermal growth factor receptor (EGFR) is known to be overexpressed in ~30% of gastric cancer (GC) cases, and may serve as an effective biomarker for predicting the clinical benefit of anti-EGFR therapy. However, the mechanism underlying the regulation of EGFR expression remains unknown.
Ning T   +14 more
europepmc   +4 more sources

Circular RNA circ_0003204 inhibits proliferation, migration and tube formation of endothelial cell in atherosclerosis via miR-370-3p/TGFβR2/phosph-SMAD3 axis

open access: yesJournal of Biomedical Science, 2020
Background Circular RNAs (circRNAs) represent a class of non-coding RNAs (ncRNAs) which are widely expressed in mammals and tissue-specific, of which some could act as critical regulators in the atherogenesis of cerebrovascular disease.
Shanchao Zhang   +8 more
doaj   +1 more source

miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition

open access: yesDrug Design, Development and Therapy, 2020
Lianjie Lin,1 Dongxu Wang,1 Suxuan Qu,1 Hong Zhao,1,2 Yan Lin1 1Department of Gastroenterology and Hepatology, Shengjing Hospital of China Medical University, Shenyang 110004, People’s Republic of China; 2Department of Gastroenterology, The Second ...
Lin L, Wang D, Qu S, Zhao H, Lin Y
doaj  

MiRNAs Regulating Insulin Sensitivity Are Dysregulated in Polycystic Ovary Syndrome (PCOS) Ovaries and Are Associated With Markers of Inflammation and Insulin Sensitivity

open access: yesFrontiers in Endocrinology, 2019
Objective: MicroRNAs (miRNAs) are gene expression regulators. Altered miRNA levels are associated with diabetes, insulin resistance, and inflammation. Insulin resistance and inflammation are both features of Polycystic ovary syndrome (PCOS).
Francesca Cirillo   +7 more
doaj   +1 more source

Effects of miR-1236-3p and miR-370-5p on activation of p21 in various tumors and its inhibition on the growth of lung cancer cells

open access: yesTumor Biology, 2017
The mechanism of dsRNA-induced gene activation (RNAa) is being gradually unveiled. The plentiful evidence that it existed in mammalian species other than human demonstrated that dsRNA-mediated RNAa is a conservative phenomenon.
Chuanchang Li   +6 more
doaj   +1 more source

Dysregulation of TCONS_00006091 contributes to the elevated risk of oral squamous cell carcinoma by upregulating SNAI1, IRS and HMGA2

open access: yesScientific Reports
In this study, we aimed to study the role of TCONS_00006091 in the pathogenesis of oral squamous cellular carcinoma (OSCC) transformed from oral lichen planus (OLP).
Danhua Ma   +6 more
doaj   +1 more source

Circular RNA hsa_circ_0003496 Contributes to Tumorigenesis and Chemoresistance in Osteosarcoma Through Targeting (microRNA) miR-370/Krüppel-Like Factor 12 Axis

open access: yesCancer Management and Research, 2020
Chaofan Xie,1,* Guanzhao Liang,2,* Yinfeng Xu,1 Erhu Lin3 1Department of Orthopaedics, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong Province, People’s Republic of China; 2Department of Emergency, The First ...
Xie C, Liang G, Xu Y, Lin E
doaj  

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