Results 131 to 140 of about 5,620 (185)

Absence of the dystrophin protein in Duchenne muscular dystrophy: effects on transcriptome, proteome and microRNA secretome [PDF]

, 2013
Duchenne muscular dystrophy (DMD) is a classical monogenic disorder characterised by severe muscle weakness. Progressive muscle loss ultimately culminates in fatality due to failure of the heart and diaphragm muscles, typically in the 2nd-4th decade of ...
van Westering, Tirsa
core   +2 more sources

Interaction of High-Fat Diet and Brain Trauma Alters Adipose Tissue Macrophages and Brain Microglia Associated With Exacerbated Cognitive Dysfunction [PDF]

Obesity increases the morbidity and mortality of traumatic brain injury (TBI). Detailed analyses of transcriptomic changes in the brain and adipose tissue were performed to elucidate the interactive effects between high-fat diet-induced obesity (DIO) and
Barrett, James P, Faden, Alan I, Henry, Rebecca J, Khan, Niaz Z, Makarevich, Oleg, Ritzel, Rodney M, Stoica, Bogdan A, Vaida, Maria   +7 more
core   +2 more sources

Circulating extracellular vesicular microRNA signatures in early gestation show an association with subsequent clinical features of pre-eclampsia. [PDF]

In a prospective cohort of subjects who subsequently developed preeclampsia (PE, n = 14) versus remaining healthy (NORM, n = 12), early gestation circulating extracellular vesicles (EVs) containing a panel of microRNA signatures were characterized and ...
Devaskar, Sherin, Fong, Jeanette, Ghosh, Shubhamoy, Janzen, Carla, Lei, Margarida, Thamotharan, Shanthie   +5 more
core   +1 more source

Correction to: CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling [PDF]

, 2020
Junxin Chen, Gang Liu, Yizheng Wu, Jianjun Ma, Hong-Fei Wu, Ziang Xie, Shuai Chen, Yute Yang, Shengyu Wang, Panyang Shen, Yifan Fang, Shunwu Fan, Shuying Shen, Xiangqian Fang   +13 more
openalex   +1 more source

Upregulation of circ_0076684 in osteosarcoma facilitates malignant processes by mediating miRNAs/CUX1

Journal of Orthopaedic Surgery and Research
Circular RNAs (circRNAs) are a newly appreciated type of endogenous noncoding RNAs that play vital roles in the development of various human cancers, including osteosarcoma (OS).
Pengfei Cai, Xin Fu, Xiaofei Li, Wei Zhao   +3 more
doaj   +1 more source

In-silico pharmacological insights into the therapeutic potential of microRNAs for microplastic-associated cancers

Frontiers in Cell and Developmental Biology
Microplastics (MPs) are increasingly implicated in cancer biology through effects on gene expression, stress responses, and treatment susceptibility; however, causal links remain provisional.
Akmaral Baspakova, Afshin Zare, Nadiar M. Mussin, Nader Tanideh, Nader Tanideh, Kulyash R. Zhilisbayeva, Ramazon Safarzoda Sharoffidin, Roza Suleimenova, Gulden Yelgondina, Akmeiir E. Kaliyeva, Aigerim A. Umbetova, Ainur Zinaliyeva, Amin Tamadon, Amin Tamadon   +13 more
doaj   +1 more source

Profiling miRNA changes in Epstein-Barr virus lytic infection identifies a function for BZLF1 in upregulating miRNAs from the DLK1-DIO3 locus.

PLoS Pathogens
Cellular and viral miRNAs are thought to play important roles in regulating Epstein-Barr virus (EBV) latent and lytic infections, however, to date, most studies have focussed on latent infections in B cells.
Ashley M Campbell, Victoria C Taylor, Beata Cohan, Lori Frappier   +3 more
doaj   +1 more source

Circular RNA hsa_circ_0004689 (circSWT1) promotes NSCLC progression via the miR-370-3p/SNAIL axis by inducing cell epithelial-mesenchymal transition (EMT). [PDF]

Cancer Med, 2023
Long X, Wang DG, Wu ZB, Liao ZM, Xu JJ.
europepmc   +1 more source

Deficiency of a novel lncRNA-HRAT protects against myocardial ischemia reperfusion injury by targeting miR-370-3p/RNF41 pathway. [PDF]

Front Cardiovasc Med, 2022
Zheng X, Zhong T, Yu F, Duan J, Tang Y, Liu Y, Li M, Sun D, Yin D.   +8 more
europepmc   +1 more source

Exosomal MicroRNA Signatures in Central Nervous System Diseases [PDF]

, 2018
During the last decade there has been a growing interest in studying extracellular vesicles, in particular exosomes and their miRNA contents. Exosomes are released by almost all cell types.
Ebrahimkhani, Saeideh
core