MiR-370 sensitizes chronic myeloid leukemia K562 cells to homoharringtonine by targeting Forkhead box M1 [PDF]
Journal of Translational Medicine, 2013 Abstract Background Homoharringtonine (HHT) is a kind of cephalotaxus alkaloid used in traditional Chinese medicine. Although HHT has been successfully used as a therapeutic agent for leukemia, the drug resistance and toxicity are major concerns. MicroRNAs (miRNAs) have been identified to modulate cellular sensitivity
Zhou, MinRan +9 more
openaire +5 more sources
CircTRRAP Knockdown Has Cardioprotective Function in Cardiomyocytes via the Signal Regulation of miR-370-3p/PAWR Axis [PDF]
Cardiovascular Therapeutics, 2022 Background. Circular RNA Transformation/Transcription Domain Associated Protein (circTRRAP, hsa_circ_0081241) was abnormally upregulated in acute myocardial infarction (AMI) patients. However, its biological role and functional mechanism in AMI remain to
Yuan Zhang +5 more
doaj +2 more sources
CircRNA_1809 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells through miR-370-3p [PDF]
Scientific ReportsCircular RNA (circRNA) is a unique closed ring structure of noncoding RNA. Although many human diseases have been confirmed to be inextricably linked with circRNAs, whether circRNAs have a potential regulatory function in the osteogenic differentiation ...
Lei Zhang +6 more
doaj +2 more sources
miR-370 mimic inhibits replication of Japanese encephalitis virus in glioblastoma cells
Neuropsychiatric Disease and Treatment, 2016 Wenjuan Li,1 Peng Cheng,2 Shangdan Nie,1 Wen Cui1 1School of Forensic and Laboratory Medicine, Jining Medical University, 2Shandong Academy of Medical Sciences, Shandong Institute of Parasitic Diseases, Jining, People’s Republic of ...
Li W, Cheng P, Nie S, Cui W
doaj +5 more sources
The protective effect of bone marrow-derived mesenchymal stem cells in liver ischemia/reperfusion injury via down-regulation of miR-370 [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Liver transplantation is the most important therapy for end-stage liver disease and ischemia reperfusion (I/R) injury is indeed a risk factor for hepatic failure after grafting. The role of miRNAs in I/R is not completely understood.
Mohamad Ali Zare +3 more
doaj +3 more sources
lncRNA NEAT1 mediates sepsis progression by regulating Irak2 via sponging miR-370-3p [PDF]
Biology Open, 2020 Sepsis is a life-threatening condition and often associated with multiple organ failure. Nuclear-enriched abundant transcript 1 (NEAT1), a member of the long non-coding RNAs (lncRNAs), was reported to be involved in the regulation of sepsis progression ...
Ting Xiao +3 more
doaj +3 more sources
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway. [PDF]
Int J Biol Sci, 2022 Increasing evidence suggests that circular RNAs (circRNAs) are involved in regulating tumor biological activity. Glioblastoma (GBM) is one of the most lethal diseases characterized by highly aggressive proliferative and invasive behaviors. We aimed to explore how circRNAs influenced GBM biological activity.
Li B, Chen J, Wu Y, Luo H, Ke Y.
europepmc +3 more sources
miR-370 Expression Analysis in Breast Cancer
مجله دانشکده پزشکی اصفهان, 2015 Background: MicroRNAs (MiRNAs) are 21-24 nucleotides which have different levels of expression between tumors and normal tissues. In this study, we analyzed the expression level of miR-370 in different stages and grades of human breast cancer tissues ...
Halimeh Mollainezhad +5 more
doaj +1 more source
CircRNA circFOXK2 facilitates oncogenesis in breast cancer via IGF2BP3/miR-370 axis. [PDF]
Aging (Albany NY), 2021 Metastasis is the leading cause of breast cancer (BC)-related deaths. Circular RNAs (circRNAs) have emerged as essential regulators for cancer progression and metastasis. Therefore, the objective of this study was to investigate the role of circRNAs in BC metastasis and related mechanism.
Zhang W +5 more
europepmc +4 more sources
circITGA7 Acts as a miR-370-3p Sponge to Suppress the Proliferation of Prostate Cancer. [PDF]
J Oncol, 2021 Abstract Objective: Prostate cancer (PCa) refers to one of the most common tumors in male’s genitourinary system. Emerging research has confirmed that circRNAs play an important role in the occurrence and development of tumors. However, the correlation between circular RNA circITGA7 and PCa still remains unclear.
Luo G +5 more
europepmc +4 more sources