Results 1 to 10 of about 3,781 (142)

miR-379-5p Inhibited the Proliferation of Acute Myeloid Leukemia Cells Through Negative Regulation of YBX1 [PDF]

Turkish Journal of Hematology
Objective: Acute myeloid leukemia (AML) highly lethal hematological malignancy that is difficult to treat. This study aimed to clarify the molecular mechanisms of miR-379-5p in AML progression.
Huichao Wu, Lin Zhao, Huanyu Guo, Yingjie Xie, Jianhua Hu, Xinxia Tan   +5 more
doaj   +6 more sources

miR-379-5p affects breast cancer cell behavior by targeting UBE2E3 ubiquitin conjugating enzyme. [PDF]

PLoS ONE
MicroRNAs (miRNAs) play an increasingly recognized role in modulating cancer development. Due to their function in regulating gene expression, miRNAs can suppress or promote tumorigenesis. miR-379-5p expression is downregulated in multiple human cancers,
Araya K Schroder, Conor J Loy, Fernanda Aiala, Jazmyn Rafique, Arnob Ghosh, Lina I Yoo   +5 more
doaj   +8 more sources

Androgen-induced exosomal miR-379-5p release determines granulosa cell fate: cellular mechanism involved in polycystic ovaries [PDF]

Journal of Ovarian Research, 2023
Polycystic ovarian syndrome (PCOS) is a complex multi-factorial syndrome associated with androgen excess and anovulatory infertility. In the current study, we investigated the role of dihydrotestosterone-induced exosomal miR-379-5p release in determining
Reza Salehi, Brandon A. Wyse, Meshach Asare-Werehene, Fereshteh Esfandiarinezhad, Atefeh Abedini, Bo Pan, Yoko Urata, Alex Gutsol, Jose L. Vinas, Sahar Jahangiri, Kai Xue, Yunping Xue, Kevin D. Burns, Barbara Vanderhyden, Julang Li, Yutaka Osuga, Dylan Burger, Seang-Lin Tan, Clifford L. Librach, Benjamin K. Tsang   +19 more
doaj   +5 more sources

Granulosa cell-derived miR-379-5p regulates macrophage polarization in polycystic ovarian syndrome [PDF]

Frontiers in Immunology, 2023
Polycystic ovarian syndrome (PCOS) is associated with hyperandrogenemia and ovarian antral follicle growth arrest. We have previously demonstrated that androgen-induced exosomal release of miR-379-5p (miR379) from preantral follicle granulosa cells ...
Reza Salehi, Reza Salehi, Reza Salehi, Reza Salehi, Meshach Asare-Werehene, Meshach Asare-Werehene, Meshach Asare-Werehene, Brandon A. Wyse, Atefeh Abedini, Bo Pan, Alex Gutsol, Sahar Jahangiri, Peter Szaraz, Kevin D. Burns, Barbara Vanderhyden, Barbara Vanderhyden, Barbara Vanderhyden, Julang Li, Dylan Burger, Dylan Burger, Dylan Burger, Clifford L. Librach, Clifford L. Librach, Clifford L. Librach, Clifford L. Librach, Benjamin K. Tsang, Benjamin K. Tsang, Benjamin K. Tsang   +27 more
doaj   +4 more sources

MiR‐379‐5p inhibits the proliferation, migration, and invasion of breast cancer by targeting KIF4A [PDF]

Thoracic Cancer, 2022
Background Many studies have shown that microRNAs (miRNAs) play an essential role in gene regulation and tumor development. This study aimed to explore the expression of miR‐379‐5p and its mechanisms of affecting proliferation, migration, and invasion in
Ke Yang, Danyang Li, Weihui Jia, Yanmei Song, Ningxin Sun, Jiemin Wang, Hongli Li, Chonggao Yin   +7 more
doaj   +4 more sources

Circ_0010235 confers cisplatin resistance in lung cancer by upregulating E2F7 through absorbing miR‐379‐5p [PDF]

Thoracic Cancer, 2023
Background Cisplatin (DDP) treatment is one of the most predominant chemotherapeutic strategies for lung cancer patients. Circular RNAs (circRNAs) have been revealed to participate in the chemoresistance in lung cancer.
Lifei Wang, Dongchang Wang, Zhen Xu, Yali Qiu, Gang Chen, Furong Tan   +5 more
doaj   +4 more sources

Memory-promoting function of miR-379-5p attenuates CD8+ T cell exhaustion by targeting immune checkpoints [PDF]

Journal for ImmunoTherapy of Cancer
Background MicroRNAs (miRNAs) are epigenetic regulators of T cell maturation and exhaustion. However, the mechanisms by which miRNAs influence T cell function in tumor environments remain unclear.
Chia-Hsin Liu, Hong-Wei Li, Liang-Chih Liu, You-Zhe Lin, Wan-Rong Wu, Ting-Yi Liao, Chuan-Chun Lee, Feng-Chi Chung, Yi-Chun Shen, Guan-Yu Zhuo, Wei-Chung Cheng, Shao-Chun Wang   +11 more
doaj   +4 more sources

hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p [PDF]

Scientific Reports
Circular RNAs (circRNAs) are widely involved in diverse biological processes of cancers. Nonetheless, the potential function of hsa_circ_0008305 in hepatocellular carcinoma (HCC) remains largely unknown.
Shenglan Huang, Kan Liu, Yongkan Xu, Hua Wang, Shumin Fu, Jianbing Wu   +5 more
doaj   +4 more sources

Expression Analysis of miR-519a-3p and miR-379-5p in Colorectal Cancer Patients: A Combined Experimental and Bioinformatic Approach [PDF]

Diagnostics
Background/Objectives: Colorectal cancer (CRC) is one of the most common malignancies worldwide. microRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression post-transcriptionally and have emerged as important regulators in cancer
Turkan Gurer, Mehmet Emin Kizakoglu, Alper Aytekin, Rusen Avsar   +3 more
doaj   +3 more sources

MIR-379-5p Expression in Endometrial Cancer and Its Correlation with ROR1 Expression. [PDF]

Asian Pac J Cancer Prev, 2023
To asses miR-379-5p expression in endometrial cancer (EC) and its correlation with ROR1 expression and to investigate the relation between miR-379-5p and ROR1 expressions and the clinicopathological picture of EC.Fifty female of EC were joined to this study.
Mosaad H, Abdelrahman AE, Abdullatif A, Lashin ME, Ramadan MSH, El-Azony A, Hussien MHS.   +6 more
europepmc   +3 more sources